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Introduction Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), is a well-known complication following orthopaedic surgery. In the absence of thromboprophylaxis, incidences up to 40% have been
Faculty of Medicine, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
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Faculty of Medicine, University of Indonesia, Jakarta, Indonesia
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Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia
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; (iii) type of surgery; (iv) type, dosage, and duration of thromboprophylaxis; (v) day of mobilization; and (vi) clinical outcomes. The primary clinical outcome was VTE (DVT or PE). Secondary clinical outcomes included mortality, bleeding events, and
Department of Orthopaedic Surgery, Vejle Hospital, Vejle, Denmark
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Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Lund University, Skåne University Hospital, Department of Orthopedics, Malmö, Sweden
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Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Department of Orthopaedics and Traumatology, Turku University Hospital, Turku, Finland
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Department of Surgery, Epworth HealthCare, University of Melbourne, Melbourne, Australia
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Centre for Hip Surgery, Wrightington Hospital, Wrightington, Wigan and Leigh NHS Trust, Lancashire, United Kingdom
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Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark
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thromboembolism (VTE) and blood transfusion have also been thoroughly investigated. Pharmacological thromboprophylaxis is a standard and well-accepted peri-operative treatment. Despite treatment, risk of symptomatic VTE has been reported to be up to 6% within 90
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2007 ; 64 : 69 - 76 . 4. Eikelboom JW Mazzarol A Quinlan DJ ; American College of Chest Physicians . Thromboprophylaxis practice patterns in two Western Australian teaching hospitals . Haematologica 2004 ; 89
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MSK Lab, Imperial College London, UK
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based on VTE and bleeding risks, aiming to limit the use of anticoagulants (low molecular weight heparin (LMWH) or warfarin). In low-risk patients that have no previous history of VTE, the use of pharmacological or mechanical thromboprophylaxis with an
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two parts. Part A focussed on the currently acceptable protocols of thromboprophylaxis in patients presenting with a hip fracture without taking any anticoagulant therapy for other medical conditions. Large-scale studies providing evidence of the
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thromboprophylaxis Mobilisation on the day of THA surgery is mandatory and significantly increases the probability of early discharge compared with mobilisation on the day after surgery and decreases the time to readiness for discharge. 32 The length and type
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greater increase in wound discharge respectively when compared to the use of no pharmacological thromboprophylaxis. Lum et al 31 proposed that prolonged wound drainage due to anti-coagulation had a positive correlation with increased length of stay (LOS
Personalized Arthroplasty Society, Atlanta, Georgia, USA
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Personalized Arthroplasty Society, Atlanta, Georgia, USA
Clinique Orthopédique Duval, Laval, Quebec, Canada
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Personalized Arthroplasty Society, Atlanta, Georgia, USA
Clinique Orthopédique Duval, Laval, Quebec, Canada
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Personalized Arthroplasty Society, Atlanta, Georgia, USA
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chemical thromboprophylaxis after TKA in the general population. However, in PWH this practice is controversial, and the best treatment is still to be determined. Some authors including Cancienne et al. showed a high rate of DVT in PWH post-TKA with 3
Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
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NIHR Leeds Biomedical Research Centre, Chapel Allerton Hospital, Leeds, UK
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elderly patients exhibit higher plasma concentrations than younger patients ( 41 , 42 ). Apixaban is typically prescribed in twice-daily dosing and can be used for both thromboprophylaxis as well as treatment of venous thromboembolism ( 41