Introduction Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), is a well-known complication following orthopaedic surgery. In the absence of thromboprophylaxis, incidences up to 40% have been
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Stephanie Marrannes, Klaas Victor, Nele Arnout, Tine De Backer, Jan Victor, and Thomas Tampere
Leonard Christianto Singjie, Reynaldo Halomoan, Ifran Saleh, Endrotomo Sumargono, and Erica Kholinne
; (iii) type of surgery; (iv) type, dosage, and duration of thromboprophylaxis; (v) day of mobilization; and (vi) clinical outcomes. The primary clinical outcome was VTE (DVT or PE). Secondary clinical outcomes included mortality, bleeding events, and
Claus Varnum, Alma Bečić Pedersen, Ola Rolfson, Cecilia Rogmark, Ove Furnes, Geir Hallan, Keijo Mäkelä, Richard de Steiger, Martyn Porter, and Søren Overgaard
thromboembolism (VTE) and blood transfusion have also been thoroughly investigated. Pharmacological thromboprophylaxis is a standard and well-accepted peri-operative treatment. Despite treatment, risk of symptomatic VTE has been reported to be up to 6% within 90
Dimitrios A. Flevas, Panayiotis D. Megaloikonomos, Leonidas Dimopoulos, Evanthia Mitsiokapa, Panayiotis Koulouvaris, and Andreas F. Mavrogenis
2007 ; 64 : 69 - 76 . 4. Eikelboom JW Mazzarol A Quinlan DJ ; American College of Chest Physicians . Thromboprophylaxis practice patterns in two Western Australian teaching hospitals . Haematologica 2004 ; 89
Stefan Lazic, Oliver Boughton, Catherine F. Kellett, Deiary F. Kader, Loïc Villet, and Charles Rivière
based on VTE and bleeding risks, aiming to limit the use of anticoagulants (low molecular weight heparin (LMWH) or warfarin). In low-risk patients that have no previous history of VTE, the use of pharmacological or mechanical thromboprophylaxis with an
Ioannis Ktistakis, Vasileios Giannoudis, and Peter V. Giannoudis
two parts. Part A focussed on the currently acceptable protocols of thromboprophylaxis in patients presenting with a hip fracture without taking any anticoagulant therapy for other medical conditions. Large-scale studies providing evidence of the
Torben Bæk Hansen
thromboprophylaxis Mobilisation on the day of THA surgery is mandatory and significantly increases the probability of early discharge compared with mobilisation on the day after surgery and decreases the time to readiness for discharge. 32 The length and type
Richard Peter Almeida, Lipalo Mokete, Nkhodiseni Sikhauli, Allan Roy Sekeitto, and Jurek Pietrzak
greater increase in wound discharge respectively when compared to the use of no pharmacological thromboprophylaxis. Lum et al 31 proposed that prolonged wound drainage due to anti-coagulation had a positive correlation with increased length of stay (LOS
Achi Kamaraj, Nikhil Agarwal, K. T. Matthew Seah, and Wasim Khan
result of that pathway gives the respective total costs involved. 37 Zindel et al used a decision tree model to illustrate the decision problem of choosing rivaroxaban or enoxaparin sodium for thromboprophylaxis after total hip and knee replacement
Marilena Giannoudi and Peter V Giannoudis
elderly patients exhibit higher plasma concentrations than younger patients ( 41 , 42 ). Apixaban is typically prescribed in twice-daily dosing and can be used for both thromboprophylaxis as well as treatment of venous thromboembolism ( 41
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