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Hua Luo Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yongwei Su The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China

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Feng Xue Department of Orthopaedics, Fengxian District Central Hospital, Shanghai, People’s Republic of China

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Zhenghua Hong Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Introduction Surgery site infections (SSIs) is one of the common complications affecting surgical management and patient recovery. Related studies report that the incidence of SSIs is 1–14% ( 1 , 2 , 3 , 4 , 5 ). The incidence of SSIs is

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A Frodl Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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N Geisteuer Department of Orthopedics and Traumatology, Asklepios Hospital Harburg, Hamburg, Germany

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A Fuchs Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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T Nymark Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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H Schmal Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany
Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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combination of impaired blood supply and hyperglycemic states further increases the risk of surgical-site infections ( 3 , 4 ). In such cases, as reported by Willy et al. , closed-incisional negative pressure wound therapy (iNPWT) has shown clinical

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Duy Nguyen Anh Tran The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Bao Tu Thai Nguyen The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Tan Thanh Nguyen Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Yu-Pin Chen Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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Yi-Jie Kuo Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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impact on mental health ( 4 , 5 , 6 , 7 , 8 ). Smoking is associated with impaired wound healing and increased susceptibility to surgical site infections (SSIs) ( 9 , 10 , 11 ). SSIs, occurring in 1–20% of patients after ankle and calcaneal

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Chengxin Xie Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Liwei Zhang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Dehua Zhang Department of Emergency, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Lingjian Tao Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yong Zhao Department of Orthopedics, Shanghai Fengxian District Central Hospital, Shanghai 201400, China.

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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survival and efficacy of the knee replacement prosthesis, including poor alignment of the lower extremities, infection, aseptic loosening of the prosthesis, and anterior knee pain ( 1 ). Among these, surgical site infection (SSI) is the most common, with

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hui Yu Department of Hematology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China
Department of Hematology, Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, China

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Zhangfu Wang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Wenjun Pan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Lin Chen Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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contamination incision; and if the articles had missing data. Outcomes The primary outcome was the incidence of surgical site infection (SSI). Secondary outcomes included satisfaction and the incidence of other wound complications. Search strategy

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Philip F. Dobson Trauma and Orthopaedic Surgery, Royal Victoria Infirmary, Newcastle, UK

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Michael R. Reed Trauma and Orthopaedic Surgery, Royal Victoria Infirmary, Newcastle, UK

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further reduced infection. Despite the ongoing evolution and refinement of surgical practice, surgical site infection (SSI) remains a risk for every patient, including those undergoing primary total hip and knee arthroplasty procedures, and is associated

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Nicola Ratto University of Torino, Italy

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Chiara Arrigoni University of Torino, Italy

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Federica Rosso AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Matteo Bruzzone AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Federico Dettoni AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Davide Edoardo Bonasia AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Roberto Rossi AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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for development of surgical site infection or peri-prosthetic joint infection after elective total joint arthroplasty, according to The International Consensus on Periprosthetic Joint Infection 7 Comorbidities Poorly controlled

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Xinhuan Lei Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Jie Xiang Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hailan Yang Department of Ultrasound, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hongya Bao Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Zhong Zhu Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Introduction Surgical site infection (SSI) is a rare and serious complication of total knee arthroplasty (TKA) that can cause a poor prognosis, reduce these patients’ quality of life, and significantly increase the financial burden. Therefore

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Razvan Ene Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
Bucharest Emergency Clinical Hospital, Romania

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Mihai Nica Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Dragos Ene Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
Bucharest Emergency Clinical Hospital, Romania

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Adrian Cursaru Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Introduction Infection associated with orthopaedic implants or surgical site infections is a deleterious complication, resulting in considerable rates of morbidity and mortality. Furthermore, management of this complication is incredibly

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain

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outpatient TKA than inpatient TKA, including component failure, surgical site infection, knee stiffness and deep vein thrombosis. 14 According to Gogineni et al, outpatient total hip arthroplasty (THA) and TKA in a well-selected patient is feasible in

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