Bogdan Serban
Bogdan Serban
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Bogdan Cretu
Bogdan Cretu
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Adrian Cursaru
Adrian Cursaru
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Cornelia Nitipir
Cornelia Nitipir
Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania
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Elias University Emergency Hospital, Bucharest, Romania
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Cristina Orlov-Slavu
Cristina Orlov-Slavu
Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania
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Elias University Emergency Hospital, Bucharest, Romania
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Catalin Cirstoiu
Catalin Cirstoiu
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Introduction Soft tissue sarcomas (STS) represent a heterogeneous group of malignancies that are all distinguished by mesodermal differentiation, with unique clinical and pathologic characteristics. Only 1% of adult malignancies are STS, which
Maria Anna Smolle
Maria Anna Smolle
Medical University of Graz, Austria
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Dimosthenis Andreou
Dimosthenis Andreou
Münster University Hospital, Germany
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Per-Ulf Tunn
Per-Ulf Tunn
Sarcoma Center Berlin-Brandenburg, HELIOS Klinikum Berlin-Buch, Germany
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Joanna Szkandera
Joanna Szkandera
Medical University of Graz, Austria
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Bernadette Liegl-Atzwanger
Bernadette Liegl-Atzwanger
Medical University of Graz, Austria
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Andreas Leithner
Andreas Leithner
Medical University of Graz, Austria
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Soft-tissue swellings, lumps and bumps are frequently seen in routine clinical practice. However, with an estimated annual incidence of five cases per 100 000 people in Europe, soft-tissue sarcomas (STS) are relatively rare and are outnumbered by
Maria Anna Smolle
Maria Anna Smolle
Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria
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Joanna Szkandera
Joanna Szkandera
Division of Clinical Oncology, Internal Medicine, Medical University of Graz, Graz, Austria
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Dimosthenis Andreou
Dimosthenis Andreou
Division of Orthopaedic Oncology and Sarcoma Surgery, Helios Klinikum Bad Saarow, Sarcoma Center Berlin-Brandenburg, Berlin, Germany
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Emanuela Palmerini
Emanuela Palmerini
Chemotherapy Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna University, Bologna, Italy
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Marko Bergovec
Marko Bergovec
Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria
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Andreas Leithner
Andreas Leithner
Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria
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Introduction Soft tissue sarcomas (STS) and bone sarcomas constitute rare mesenchymal neoplasms, with an incidence of 4.7 and 0.8 per 100 000 patients per year in Europe, respectively. 1 , 2 The majority of these tumours are located in
Chengxiang Li
Chengxiang Li
Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
University of Basel, Basel, Switzerland
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University of Basel, Basel, Switzerland
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Fatime Krasniqi
Fatime Krasniqi
Department of Oncology, University Hospital Basel, Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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Ricardo Donners
Ricardo Donners
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Department of Radiology, University Hospital Basel, Basel, Switzerland
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Department of Radiology, University Hospital Basel, Basel, Switzerland
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Christoph Kettelhack
Christoph Kettelhack
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland
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Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland
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Andreas H Krieg
Andreas H Krieg
Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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Introduction Synovial sarcoma (SS) is a relatively rare malignancy, accounting for 5–10% of all soft tissue sarcomas (STS) ( 1 ). All SSs are considered to be high-grade STS, characterized by local invasiveness and a propensity to metastasize
Olga Savvidou
Olga Savvidou
First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
These authors contributed equally to this manuscript
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These authors contributed equally to this manuscript
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Olympia Papakonstantinou
Olympia Papakonstantinou
Second Department of Radiology, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Athens, Greece
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These authors contributed equally to this manuscript
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Eleftheria Lakiotaki
Eleftheria Lakiotaki
First Department of Pathology, National and Kapodistrian University of Athens, LAIKON General Hospital, Athens, Greece
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These authors contributed equally to this manuscript
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Dimitra Melissaridou
Dimitra Melissaridou
First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
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Pinelopi Korkolopoulou
Pinelopi Korkolopoulou
First Department of Pathology, National and Kapodistrian University of Athens, LAIKON General Hospital, Athens, Greece
Co-senior authors
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Co-senior authors
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
Co-senior authors
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Co-senior authors
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also calcified lesions but without ‘zonal’ calcification. 3 Post-traumatic MO presents clinically with symptoms that simulate bone or soft tissue malignancies. The opposite is also true, because bone or soft tissue sarcomas, especially when there
E. Mascard
E. Mascard
Necker University Hospital, 75015 Paris, France.
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N. Gaspar
N. Gaspar
Department of Pediatrics, Institute Gustave Roussy, 94805 Villejuif, France
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L. Brugières
L. Brugières
Department of Pediatrics, Institute Gustave Roussy, 94805 Villejuif, France
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C. Glorion
C. Glorion
Orthopedic Surgery Department, Necker University Hospital, 149 rue de Sèvres, 75015 Paris, France
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S. Pannier
S. Pannier
Orthopedic Surgery Department, Necker University Hospital, 149 rue de Sèvres, 75015 Paris, France
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A. Gomez-Brouchet
A. Gomez-Brouchet
Laboratoire d'anatomie et cytologie pathologiques, Institut Universitaire du Cancer de Toulouse- Oncopole, 1 avenue Irène Joliot-Curie. 31059 Toulouse Cedex 9, France
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followed up in dermatology departments. Diagnosis of bone and soft-tissue foot tumours is often delayed and many malignant conditions are referred to specialised sarcoma teams after an initial inappropriate procedure. 4 - 6 The adverse effect of
Maria A. Smolle
Maria A. Smolle
Department of Orthopaedics and Trauma, Medical University of Graz, Austria
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Dimosthenis Andreou
Dimosthenis Andreou
Department of General Orthopaedics and Tumour Orthopaedics, University Hospital Muenster, Germany
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Per-Ulf Tunn
Per-Ulf Tunn
Tumour Orthopaedics, HELIOS Klinikum Berlin-Buch, Germany
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Andreas Leithner
Andreas Leithner
Department of Orthopaedics and Trauma, Medical University of Graz, Austria
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reconstruction of the soft tissues and a hemiarthroplasty should be best chosen to reduce instability. 10 Corresponding to this, Du et al investigated hip instability in 58 patients with total femoral replacement for sarcoma. 11 In 12 patients, a LARS
Robert Grimer
Robert Grimer
The Royal Orthopaedic Hospital, Birmingham, UK
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Michael Parry
Michael Parry
The Royal Orthopaedic Hospital, Birmingham, UK
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Steven James
Steven James
The Royal Orthopaedic Hospital, Birmingham, UK
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Soft tissue sarcomas (STS) are rare, with a combined incidence of about 60/100,000 population a year. It is generally stated that there are 100 benign soft tissue tumours for every soft tissue sarcoma. As a result of this there is a low level of
Olga D. Savvidou
Olga D. Savvidou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panagiotis Koutsouradis
Panagiotis Koutsouradis
Department of Orthopaedic Surgery, Mediterraneo Hospital, Athens, Greece
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Ioanna K. Bolia
Ioanna K. Bolia
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Angelos Kaspiris
Angelos Kaspiris
Laboratory of Molecular Pharmacology/Sector for Bone Research, School of Health Sciences, University of Patras, Patras 26504, Greece
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George D. Chloros
George D. Chloros
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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conservative approach is usually advocated. However, in cases of outsized tumours that may cause symptoms, excision or embolization is recommended. 75 Malignant soft tissue tumours of the elbow The incidence of soft tissue sarcomas (STS) in the
G. Ulrich Exner
G. Ulrich Exner
Orthopaedie Zentrum Zuerich (ozz), Seestrasse 259, CH 8038 Zurich, Switzerland
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Michael O. Kurrer
Michael O. Kurrer
Gemeinschaftspraxis fuer Pathologie, Caecilienstrasse 3, CH 8032 Zurich, Switzerland
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Nadja Mamisch-Saupe
Nadja Mamisch-Saupe
Klinik Hirslanden, Department of Musculoskeletal Radiology, Witellikerstrasse 40, 8032 Zurich, Switzerland
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Stephen R. Cannon
Stephen R. Cannon
BMI The Clementine Churchill Hospital, Sudbury Hill, Harrow, Middlesex HA1 3RX, Great Britain
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cells (cytology and/or cultures). Usually the needle is guided by ultrasound and several passes may be used to increase yield. This is usually performed under local anaesthetic. This technique is particularly useful in high-grade soft-tissue sarcoma
