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Corentin Pangaud Hôpital Sainte Marguerite, Aix Marseille Université, Marseille, France

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Matthieu Ollivier Hôpital Sainte Marguerite, Aix Marseille Université, Marseille, France

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Jean-Noël Argenson Hôpital Sainte Marguerite, Aix Marseille Université, Marseille, France

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modified through the development of static spacers 10 and then articulating spacers in 2001. 11 Single-stage exchange for periprosthetic joint infection is not a truly new technique: it was first described by Buchholz in the 1970s at the Endo

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Theofilos Karachalios Department of Orthopaedics and Musculoskeletal Trauma, University General Hospital of Larissa, Greece
School of Health Sciences, Faculty of Medicine, University of Thessalia, Larissa, Greece

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George A. Komnos Department of Orthopaedics and Musculoskeletal Trauma, University General Hospital of Larissa, Greece

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JN . Outcome of single-stage versus two-stage exchange for revision knee arthroplasty for chronic periprosthetic infection . EFORT Open Rev 2019 ; 4 : 495 – 502 . 15. McPherson EJ Woodson C Holtom P Roidis

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Chengxin Xie Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Wenjun Pan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Shouli Wang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xueli Yan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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14 222 . ( https://doi.org/10.1186/1471-2474-14-222 ) 47 Pangaud C Ollivier M & Argenson JN . Outcome of single-stage versus two-stage exchange for revision knee arthroplasty for chronic periprosthetic infection . EFORT Open Reviews 2019 4

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Ismail Remzi Tözün Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Vahit Emre Ozden Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Goksel Dikmen Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Kayahan Karaytuğ Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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a single centre . Bone Joint J 2014 ; 96-B : 759 – 764 . 48. Nagra NS Hamilton TW Ganatra S Murray DW Pandit H . One-stage versus two-stage exchange arthroplasty for infected total knee

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Congcong He Department of Psychology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yong Zhao Department of Orthopedics, Shanghai Fengxian District Central Hospital, Shanghai, China

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Guangyong Yang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hainan Hong Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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destruction is significant, a two-stage primary joint arthroplasty with bony cut and spacer may be considered to first sterilize the joint and subsequently reconstruct it. However, some authors suggest that a single-stage approach is feasible when the

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Nicolas Bonnevialle Orthopaedic Department and Biomechanics Department, IMFT CNRS URM 5502, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Florence Dauzères Orthopaedic Department, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Julien Toulemonde Orthopaedic Department, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Fanny Elia Orthopaedic Department, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Jean-Michel Laffosse Orthopaedic Department, CRIOAC and Biomechanics Department, IMFT CNRS, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Pierre Mansat Orthopaedic Department and Biomechanics Department, IMFT CNRS URM 5502, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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reported. 32 One-stage revision arthroplasty Based on the experience of knee and hip infection management, a single-stage exchange is proposed as a reasonable option when the infecting micro-organism is satisfactiorily identified. The

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Heinz Winkler Osteitis Centre, Privatklinik Döbling Wien, Heiligenstaedter Strasse 57-63, A-1190 Wien, Austria

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approaches, 18 , 19 a delayed infection definitely is chronic and always requires surgical removal of all non-viable material for cure. There is ongoing debate on the timing of re-implantation of a new prosthesis, either in one single stage or in

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Hee-Nee Pang Department of Orthopaedic Surgery, Singapore General Hospital, Singapore and Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Hamid Rahmatullah Bin Abd Razak Department of Orthopaedic Surgery, Singapore General Hospital, Singapore

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Stephen Petis Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Douglas D. R. Naudie Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Steven J. MacDonald Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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polyethylene exchange is an attractive option in treating peri-prosthetic infections because it involves a single operation. This procedure may reduce the potential morbidity associated with a two-stage re-implantation procedure, such as loss of bone stock

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Pablo A. Slullitel Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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José I. Oñativia Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Martin A. Buttaro Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Marisa L. Sánchez Infectology Department, Italian Hospital of Buenos Aires, Argentina

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Fernando Comba Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Gerardo Zanotti Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Francisco Piccaluga Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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We believe that an attempt to irrigate and debride with polyethylene exchange presents little harm to patients. However, it is controversial whether DAIR may diminish the eradication potential of a future one- or two-stage revision surgery. Sherrell

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Andy Craig Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK

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S W King Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK

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B H van Duren Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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V T Veysi Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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S Jain Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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J Palan Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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Joint Registry (NJR) data indicating 10-year revision rates of approximately 2% for a number of commonly used prostheses ( 6 ). Nonetheless, prosthetic joint infection (PJI) remains a devastating complication. Of all single- and first-stage revisions (of

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