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Leonardo Tassinari I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Alberto Di Martino I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Matteo Brunello I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Valentino Rossomando I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Francesco Traina Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy
Orthopedics-Traumatology and Prosthetic Surgery and Hip and Knee Revision, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Cesare Faldini I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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? Materials and methods Literature search This systematic review was a priori registered with the International Prospective Register of Systematic Reviews (PROSPERO) with code CRD42023412644, and we had an agreement detailing our search strategy

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Johannes D Bastian Department of Orthopaedic Surgery and Traumatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

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Silviya Ivanova Department of Orthopaedic Surgery and Traumatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

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Ahmed Mabrouk Department of Trauma and Orthopaedics, Leeds Teaching Hospitals NHS Trust, United Kingdom

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Peter Biberthaler Department of Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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Pedro Caba-Doussoux Servicio de Cirugía Ortopédica y Traumatología, Hospital 12 de Octubre, Madrid, España

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Nikolaos K Kanakaris Department of Trauma and Orthopaedics, Leeds Teaching Hospitals NHS Trust, United Kingdom
Major Trauma Centre, Leeds Teaching Hospitals NHS Trust, University of Leeds, United Kingdom

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surgeon can choose from a large number of operative methods (i.e. antegrade nail and screws around the nail ( 17 , 18 , 19 ), cephalomedullary reconstruction nails – ‘single-implant’ strategy ( 20 , 21 , 22 ), free lag screws or plate screw fixations

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T. Fintan Moriarty AO Research Institute Davos, Switzerland

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Richard Kuehl University Hospital of Basel, Switzerland

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Tom Coenye Ghent University, Belgium

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Willem-Jan Metsemakers University Hospitals Leuven, Belgium

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Mario Morgenstern Trauma Centre, Murnau, Germany

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Edward M. Schwarz University of Rochester Medical Center, New York, USA

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Martijn Riool AMC, University of Amsterdam, The Netherlands

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Sebastian A.J. Zaat AMC, University of Amsterdam, The Netherlands

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Nina Khana University Hospital of Basel, Switzerland

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Stephen L. Kates Virginia Commonwealth University, Virginia, USA

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R. Geoff Richards AO Research Institute Davos, Switzerland

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antibiotic therapy The goal of any medical strategy for the treatment of ODRI should consist of the long-term elimination of pain, restoration of function of the affected joint and, in trauma cases, consolidation of the fracture with prevention of

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Donald J. Davidson Research Department of Orthopaedics and Musculoskeletal Sciences, University College London, London, UK
Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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David Spratt Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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Alexander D. Liddle Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK
MSK Lab, Imperial College London, London, UK

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sizes or the fabrication of nanotube arrays or nanowires, has demonstrated efficacy in vitro at deterring biofilm formation. 49 – 53 The most recent strategy is to create complex self-assembled mono- or multilayers which also have excellent anti

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Pablo Castillón Department of Trauma and Orthopaedic Surgery, Hospital, Universitari Mútua Terrassa, Terrassa, Barcelona, Spain
Universidad Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain

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Josep Maria Muñoz Vives Department of Trauma and Orthopaedic Surgery, Hospital Althaia Manresa. Manresa, Barcelona, Spain
Department of Trauma and Orthopaedic Surgery, Hospital Nostra Senyora de Meritxell, Andorra

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Héctor José Aguado Department of Trauma and Orthopaedic Surgery, Hospital Clínico Universitario de Valladolid. Valladolid, Spain
Universidad de Valladolid, Valladolid, Spain

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Arantxa Capel Agundez Department of Trauma and Orthopaedic Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain

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Alina Ortega-Briones Department of Trauma and Orthopaedic Surgery, Hospital Clínico Universitario de Valladolid. Valladolid, Spain

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Jorge Hassan Núñez Department of Trauma and Orthopaedic Surgery, Hospital, Universitari Mútua Terrassa, Terrassa, Barcelona, Spain
Universidad Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain

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the PISCO Investigators †
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the PISCO Investigators

, and poor bone quality inherent to the aging process ( 6 , 7 ). Peri-prosthetic femoral fractures (PPFFs) have been extensively studied and there are different classification systems and treatment guidelines ( 8 , 9 ). Fixation strategies exist for

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Richard Peter Almeida Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Lipalo Mokete Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Nkhodiseni Sikhauli Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Allan Roy Sekeitto Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Jurek Pietrzak Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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exists after revision surgery for PJI and five-year mortality is 21%. 8 Much focus is now devoted to the prevention of PJI and the recognition and treatment of PWD should be a logical step in preventing PJI. However, evidence-based clinical guidelines

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Jennette Higgs Food to Fit Ltd., PO Box 6057, Greens Norton, Northamptonshire, NN12 8GG, United Kingdom

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Emma Derbyshire Nutritional Insight Ltd., Surrey, KT17 2AA, United Kingdom

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Kathryn Styles Food to Fit Ltd., PO Box 6057, Greens Norton, Northamptonshire, NN12 8GG, United Kingdom

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-architecture 5 with loss of oestrogen, a major regulator of bone metabolism, contributing to this. 9 Consequently, these appear to be opportune periods to tailor modifiable factors affecting bone density and quality, including nutritional prevention

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Stephanie Marrannes Department of Orthopedic Surgery, Ghent University, Belgium

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Klaas Victor Department of Orthopedic Surgery, University of Leuven, Belgium

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Nele Arnout Department of Orthopedic Surgery, Ghent University, Belgium

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Tine De Backer Department of Cardiology, Ghent University, Belgium

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Jan Victor Department of Orthopedic Surgery, Ghent University, Belgium

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Thomas Tampere Department of Orthopedic Surgery, Ghent University, Belgium

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prevention of VTE events following knee surgery. Methods This systematic review and meta-analysis was conducted in accordance with the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. 28

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Dimitrios A. Flevas First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Panayiotis D. Megaloikonomos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Leonidas Dimopoulos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Evanthia Mitsiokapa First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Panayiotis Koulouvaris First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Andreas F. Mavrogenis First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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pharmacologic agents and/or mechanical compressive devices for the prevention of VTE in patients undergoing elective THR or TKR, and who are not at elevated risk beyond that of the surgery itself for VTE or bleeding’; the AAOS, following an update in 2011

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Low-dose dexamethasone during arthroplasty

What do we know about the risks?

Jessica T. Wegener Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Tim Kraal Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Markus F. Stevens Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Markus W. Hollmann Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Gino M.M.J. Kerkhoffs Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Daniël Haverkamp Department of Orthopedic Surgery, Slotervaart Ziekenhuis, Amsterdam, The Netherlands

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substantial part of the shortened hospital stay is related to improved peri-operative pain management and prevention of post-operative nausea and vomiting (PONV), resulting in faster mobilisation and discharge of patients. Meanwhile, many peri

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