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Low-dose dexamethasone during arthroplasty
What do we know about the risks?
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substantial part of the shortened hospital stay is related to improved peri-operative pain management and prevention of post-operative nausea and vomiting (PONV), resulting in faster mobilisation and discharge of patients. Meanwhile, many peri-operative
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general weakness were the main clinical reasons for being hospitalised 24 hours and 48 hours post-operatively after THA and TKA, while nausea, vomiting, confusion and sedation delayed discharge to a minimal extent. Waiting for blood transfusion, for start
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Department of Anesthesiology, Cleveland Clinic, Cleveland, Ohio, USA
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been used in TKA. GA, historically, has been associated to high rates of postoperative nausea, vomit and delirium. 8 On the other hand, neuroaxial anesthesia reduces nausea, vomiting, cardiovascular and pulmonary complications and overall mortality
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. Patients should not show signs of delirium, nausea or vomiting; they must be able to evacuate (urinate) and maintain their vital signs without the need for intravenous fluids or oxygen. Upon hospital discharge, patients will be provided with oral
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Osteotomie Komitee der Deutschen Knie Gesellschaft (DKG), Munich, Germany
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Osteotomie Komitee der Deutschen Knie Gesellschaft (DKG), Munich, Germany
AO Research Institute Davos, Davos, Switzerland
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following medial open-wedge HTO ( 17 ). To prevent PONV (postoperative nausea and vomiting), all patients received 4 mg dexamethasone. Pehora et al. showed in their Cochrane Review, that Dexamethasone administration can prolong the duration of
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School of Health Professions Education (SHE), Maastricht University, Maastricht, the Netherlands
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School of Care and Public Health Research Institute (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands
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(e.g. tinnitus, vertigo, deafness, blindness, convulsions, headaches and peripheral neuropathy), cardiotoxicity and thyroid toxicity ( 14 ). Nausea, anorexia and unexplained weight loss have also been described ( 6 , 15 , 16 , 17 ). Initially
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, tenderness mostly in the thoracolumbar spine and localised back deformity. In addition, cervical spondylodiscitis may cause dysphagia or torticollis. 57 Other non-specific symptoms include malaise, lethargy, confusion, nausea, vomiting, anorexia and
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severe complication that may arise if the lesion is located in the cranial bones, especially the skull base, or in the spine, and can be caused by the formation of a fistula. CSF leakage can cause symptoms like headache, vomiting, nausea and cranial