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Introduction Advances in pharmacology and our understanding of acute paediatric osteoarticular infections have led to significant reductions in associated mortality. 1 , 2 These infections are still, however, associated with significant
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management can lead to serious and permanent musculoskeletal morbidities such as joint destruction, dislocation and physeal growth arrest. Childhood septic arthritis and acute haematogenous osteomyelitis are thus regarded as top paediatric emergencies. The
King’s Global Health Partnerships, School of Life Course and Population Sciences, King’s College London, London, UK
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Department of Orthopaedics, University of the Philippines, Philippine General Hospital Manila, The Phillipines
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Introduction and aims The global burden of fracture-related infection (FRI) is likely to be concentrated in countries with limited healthcare resources. Conditions associated with FRI (road injuries, other musculoskeletal disorders, falls and
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musculoskeletal lesions: a prospective study of 128 cases . Skeletal Radiol 2006 ; 35 : 138 - 143 . 28 Sebire NJ , Roebuck DJ . Pathological diagnosis of paediatric tumours from image-guided needle core biopsies: a systematic review
Co-first authors and equal contributors
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Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
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Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
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Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
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Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
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. Bacteriophage application for difficult-to-treat musculoskeletal infections: development of a standardized multidisciplinary treatment protocol . Viruses 2019 ; 11 : 891 . 34. Nir-Paz R Gelman D Khouri A , et al. Successful
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-union, while post-operative infections and iatrogenic radial nerve palsy (iRNP) do naturally occur following surgical therapy. As complication profiles are known to differ between conservative and surgical therapy, operative techniques, and implant types, but
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presentation is not indicative of benignity or malignancy ( 7 , 8 ). The DD with an infection is mandatory in children, as this is far more common than sarcoma in all paediatric ages ( 9 ). Trauma is also very common in paediatric ages, so previous traumatic
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descriptive features of each domain are shown in Table 1 . This systematic approach focuses on the patho-anatomy of the injury and is believed to be applicable to open fractures of all bones in both adult and paediatric cases. 9 Agel et al have conducted
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circulation, even though this type is predominately encountered in paediatric populations. 3 , 9 In adults, it typically occurs secondarily from a distal site of infection, often involving the vertebral bodies of the lower spine and can also be associated
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F Segur JM Ullot R et al. Non-invasive expandable prosthesis in musculoskeletal oncology paediatric patients for the distal and proximal femur: first results . Int Orthop 2016 ; 40 : 1683 – 1688 . 47
