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Introduction Orthopaedic prosthetic joint infection (PJI) is a specific type of infection related to joint replacement and associated with biofilm formation on the surface of the inert implant. With an overall incidence between 1% and 5
School of Health Sciences, Faculty of Medicine, University of Thessalia, Larissa, Greece
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implant retention) is also indicated for early or acute infections. Other strategies, with specific indications, which are less popular and produce poorer results, include antibiotic suppression, arthrodesis, and even amputation. 6 The cost of
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importance to control the growing problem of antibiotic resistance. However, because of the high risk of bacterial biofilm infections, their prophylactic use in invasive orthopaedic implant procedures appears justified. Antibiotic-loaded bone cement and other
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. Cochrane Database Syst Rev 2013 ; 1 :CD006353. 38 Boekel P Blackshaw R Van Bavel D Riazi A Hau R . Sterile stockinette in orthopaedic surgery: a possible pathway for infection . ANZ J Surg 2012 ; 82
Bucharest Emergency Clinical Hospital, Romania
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University Emergency Hospital Bucharest, Romania
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Bucharest Emergency Clinical Hospital, Romania
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University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Introduction Infection associated with orthopaedic implants or surgical site infections is a deleterious complication, resulting in considerable rates of morbidity and mortality. Furthermore, management of this complication is incredibly
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PTTF retrospectively included – mean follow up of 5.3 years, with an implant, limb and prosthesis survival of 90%, 100% and 80%, respectively – four failures occurred (two infections, two mechanical failures) –> one amputation for infected prosthesis
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should be assessed for consistency with the patients’ history and findings from the physical examination before coming to a final impression. The evidence shows that implant failure is most commonly for two reasons, aseptic loosening or infection, where
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Biomechatronics Group, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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that there are different degrees of biofilm production by bacteria causing implant-associated infection, which may influence future decision making by orthopaedic surgeons. 39 Porous titanium alloy flanges that are coated with fibronectin
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infection in patients with delayed, but not early, orthopaedic implant failure . Bone Joint J 2013 ;95-B: 244 – 249 . 52. Portillo ME Salvadó M Alier A et al. Advantages of sonication fluid culture for the diagnosis
Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK
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MSK Lab, Imperial College London, London, UK
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; 16 : 397 – 409 . 19. Tande AJ Patel R . Prosthetic joint infection . Clin Microbiol Rev 2014 ; 27 : 302 – 345 . 20. Zimmerli W . Clinical presentation and treatment of orthopaedic implant