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. Comparison: to compare the functional and oncological results obtained after surgical treatment of distal femur and/or proximal tibia GCTs. Outcomes: local recurrence of the disease; ROM; infection; need for surgical revision; metastatic disease
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surgical techniques allows demanding reconstructions ( 19 , 20 , 21 , 22 ). With the use of CAS and custom 3D-printed reconstructions, satisfactory results in terms of functional and oncological outcomes have been also reported in recent series of
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oncological, radiotherapeutic, and surgical treatment must be determined exactly. Even in the case of a patient with a short life expectancy, the functional outcome following reconstruction resection will be significantly improved, with improvement occurring
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of these conditions are present, an aggressive surgical approach is justified by the evidence of better oncologic outcomes in the mid and long term ( 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 ). In most recent years, many patients have been
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excision of bone sarcoma is valid if the resection performed achieves oncologic safe margins, clear of any tumour tissue, and the functional results and survival rates expected are equal or better than after an amputation performed for the same case ( Fig
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demonstrated decreased pain, improved functional outcome scores and range of motion following revision surgery. Complication rate was reasonably high, with 12 (18%) shoulders requiring repeat revision surgery. Melis et al reported on 37 consecutive anatomical
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interventions that will lead to positive functional outcomes involves five main points, which will be discussed further. These include: understanding the disease background, pre-operative patient management, the surgical strategy, post-operative care, and the
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, Liang et al compared the functional and oncological outcomes of 62 cases with uncemented tibial fixation and 58 cases with cemented tibial fixation in distal femoral replacement for bone tumours. 29 Osseointegration was observed in 64.3% of patients
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-reported outcome measures (PROMs) blur the boundaries between two aspects of amputation: the best surgical option OR the best possible medical care strategy to improve functional outcome and quality of life after failed surgery for infection, tumours or certain
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studies, conservative treatment, curettage and grafting, review articles), or studies not reporting on functional outcomes after surgery. The reviewers independently screened titles and abstracts of all identified studies. Studies were further included in