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diseases of accessory cells characterized by the typical Langerhans cells. 4 , 5 Non-Langerhans cell histiocytosis (N-LCH) summarizes a group of rare diseases with different clinical presentations, pathogenesis and morphology. These include primary
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0-5 years Osteomyelitis Osteofibrous dysplasia Metastatic neuroblastoma Metastatic rhabdomyosarcoma Leukaemia 5-20 years Langerhans cell histiocytosis (Eosinophilic granuloma) Osteomyelitis Fibrous dysplasia Osteosarcoma
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is frequently observed. No cases have been reported in the foot. Langerhans cell histiocytosis The predilection age of Langerhans cell histiocytosis (LCH), historically also referred to as eosinophilic granuloma, is the first and second decade
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, lytic metastasis from an unknown primary tumor, Hajdu–Cheney syndrome, Paget’s disease, rheumatoid arthritis, fibrous dysplasia, Langerhans cell histiocytosis, Winchester syndrome (type V of Hardegger classification), carpal tarsal osteolysis (type I