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Olivier Courage Ramsay Santé, Hopital Prive de l'Estuaire, LeHavre, France

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Louise Strom ReSurg SA, Nyon, Switzerland

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Floris van Rooij ReSurg SA, Nyon, Switzerland

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Matthieu Lalevée Ramsay Santé, Hopital Prive de l'Estuaire, LeHavre, France
Hôpital Charles Nicolle, CHU de Rouen, Rouen, France

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Donatien Heuzé Ramsay Santé, Hopital Prive de l'Estuaire, LeHavre, France
Hôpital Charles Nicolle, CHU de Rouen, Rouen, France

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Pierre Emanuel Papin Ramsay Santé, Hopital Prive de l'Estuaire, LeHavre, France
Hôpital Charles Nicolle, CHU de Rouen, Rouen, France

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Michael Butnaru Ramsay Santé, Hopital Prive de l'Estuaire, LeHavre, France
Hôpital Charles Nicolle, CHU de Rouen, Rouen, France

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Jacobus Hendrik Müller ReSurg SA, Nyon, Switzerland

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elderly patients. 8 , 9 Furthermore, some studies reported higher complication rates, length of stay (LoS) in hospital, and mortality following TKA in older patients, 6 , 10 – 12 whilst other studies argued that these outcomes depend more on morbidities

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Te-Feng Arthur Chou Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Hsuan-Hsiao Ma Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Shang-Wen Tsai Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Cheng-Fong Chen Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Po-Kuei Wu Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Wei-Ming Chen Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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arthroplasty surgery due to several risk factors such as morbid obesity, alcohol abuse, and poorly controlled diabetes. 2 , 3 In addition, these patients have been shown to have a higher mortality and morbidity rate following arthroplasty surgeries. 4

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Pietro Feltri Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland

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Camilla Mondini Trissino da Lodi Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland

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Alberto Grassi II Clinica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Stefano Zaffagnini II Clinica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Christian Candrian Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland
Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland

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Giuseppe Filardo Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland
Applied and Translational Research Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland

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, reintervention, and mortality, transfusion rates, and days to discharge was assessed using a z test on the pooled rates with their corresponding 95% CIs. Subgroup analyses for complications between single and double-stage techniques were made. A P value of 0

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Yangqi Xu Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia

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Tony B Huang Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia

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Michael A Schuetz Jamieson Trauma Institute, Metro North Hospital and Health Service, Queensland Health, Brisbane, Queensland, Australia
Department of Orthopaedic Surgery, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia
Queensland University of Technology (QUT), Brisbane, Queensland, Australia

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Peter F M Choong Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia
Department of Orthopaedics, St. Vincent’s Hospital, Fitzroy, Victoria, Australia

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the ICARAUS group
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the ICARAUS group

diagnoses may be impacted by the subjectivity of clinicians, which was infeasible to adjust for in this review. Included studies reported at least one of the following main outcomes: mortality rate, patient-reported QoL, or the economic impact of PJI such as

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Arvin Eslami Bone and Joint reconstruction research center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran
Firoozgar Hospital, Bone and Joint reconstruction research center, Iran University of Medical Sciences, Tehran, Iran
Department of Orthopedic, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

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Mohammadreza Chehrassan Bone and Joint reconstruction research center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran
Department of Orthopedic, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

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Shaya Alimoghadam Bone and Joint reconstruction research center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran
Firoozgar Hospital, Bone and Joint reconstruction research center, Iran University of Medical Sciences, Tehran, Iran
Department of Orthopedic, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

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Karim Pisoudeh Bone and Joint reconstruction research center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran
Firoozgar Hospital, Bone and Joint reconstruction research center, Iran University of Medical Sciences, Tehran, Iran
Department of Orthopedic, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

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Amir Kasaeian Digestive Oncology Research Center, Digestive Diseases Research Institute; Research Center for Chronic Inflammatory Diseases; Clinical Research Development Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

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Omid Elahifar Bone and Joint reconstruction research center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran
Firoozgar Hospital, Bone and Joint reconstruction research center, Iran University of Medical Sciences, Tehran, Iran
Department of Orthopedic, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

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-induced fractures is reported to range from 5 to 8%. The associated mortality rates are reported as 9% for mothers and up to 60% for fetuses. This significant mortality rate is influenced by various factors. PRFs that lead to hypovolemia can independently escalate

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A Frodl Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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N Geisteuer Department of Orthopedics and Traumatology, Asklepios Hospital Harburg, Hamburg, Germany

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A Fuchs Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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T Nymark Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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H Schmal Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany
Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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level of evidence according to the Oxford Centre of Evidence-Based Medicine ( 10 ). Outcome criteria Patient demographics, number of patients, type of iNPWT procedure, post-surgical 30-day mortality, readmission, and wound complication rate were

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Allan Roy Sekeitto Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Nkhodiseni Sikhauli Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Dick Ronald van der Jagt Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Lipalo Mokete Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Jurek R.T. Pietrzak Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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, and limited outcomes. 33 A systematic review reported worse mobility scores, pain scores and mortality rates in non-operative treatment. 32 ii) Operative treatment Optimal surgical management of displaced FNFs especially in the elderly

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Ting-Yu Tu Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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Chun-Yu Chen Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan
Department of Occupational Therapy, Shu-Zen Junior College of Medicine and Management, Kaohsiung City, Taiwan
Department of Biomedical Engineering, I-Shou University, Kaohsiung City, Taiwan

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Pei-Chin Lin Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
Department of Pharmacy, School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan

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Chih-Yang Hsu Department of Internal Medicine, Division of Nephrology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

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Kai-Cheng Lin Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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, and reoperation rate and mortality rate of ORIF alone vs aTHA with/without ORIF (limited ORIF) in acetabular fractured elderlies. Method Search strategy The study was performed in accordance with the Preferred Reporting Items for Systematic

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Michael de Buys Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa

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Krisantha Moodley Emergency Department, ER Consulting, Johannesburg, South Africa

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Josip Nenad Cakic Department Orthopaedic Surgery, Life Fourways Hospital, Johannesburg, South Africa

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Jurek R T Pietrzak Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa

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morbidity and mortality rates and costs ( 9 , 13 ). Optimization of patients and their risk factors pre-operatively remains a fundamental strategy to mitigate the impact of PJI ( 9 ). Screening and decolonization of S. aureus prior to TJA is a

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Andreas F. Mavrogenis Attikon General University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Panayiotis D. Megaloikonomos Attikon General University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Vasileios G. Igoumenou Attikon General University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Georgios N. Panagopoulos Attikon General University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Efthymia Giannitsioti Attikon General University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Antonios Papadopoulos Attikon General University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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Panayiotis J. Papagelopoulos Attikon General University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

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or subdural abscess formation, neurological impairment and high morbidity and mortality rates. 44 Direct bacterial inoculation is mainly iatrogenic. A diagnostic or therapeutic spinal procedure may inoculate bacteria and contaminate the spine

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