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Thomas M Grupp Aesculap AG, Research & Development & Medical Scientific Affairs, Tuttlingen, Germany
Ludwig Maximilians University Munich, Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Munich, Germany

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Sabine Rusch Aesculap AG, Research & Development & Medical Scientific Affairs, Tuttlingen, Germany

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Philippe Massin CMC Ambroise-Paré-Hartmann, Neuilly-sur-Seine, France

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Ashley Blom National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, UK
Translational Health Sciences, Bristol Medical School, Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK

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Eduardo Garcia-Rey Hôpital Universitario La Paz-Idi Paz, Madrid, Spain
Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, Madrid, Spain

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Luca Cristofolini Department of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum - Università di Bologna, Bologna, Italy

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Dennis Janssen Radboud University Medical Center, Radboud Research Institute, Orthopaedic Research Lab, Nijmegen, the Netherlands

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Bernd Grimm Luxembourg Institute of Health, Human Motion, Orthopaedics, Sports Medicine & Digital Methods Group, Transversal Activities, Luxembourg

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Alexander Giurea Department of Orthopaedic Surgery, Medical University of Vienna, Vienna, Austria

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Marcus Jäger Department of Orthopaedics, Trauma & Reconstructive Surgery St. Marien Hospital Mülheim an der Ruhr & Chair of Orthopaedics and Trauma Surgery University of Duisburg–Essen, Essen, Germany

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Francesco Siccardi Medacta International SA, Research & Development & Medical Affairs, Castel San Pietro, Switzerland

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Søren Overgaard Copenhagen University Hospital, Department of Orthopaedic Surgery and Traumatology, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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-quality recommendation statements and afterwards define consensus amongst participants. A modified Delphi approach plus additional elements such as a preparatory literature review and work in small groups were used in the first phase. Aim was to generate a solid

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Maria E Dey Hazra Steadman Philippon Research Institute, Vail, Colorado, USA

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Rony-Orijit Dey Hazra Steadman Philippon Research Institute, Vail, Colorado, USA

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Jared A Hanson Steadman Philippon Research Institute, Vail, Colorado, USA

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Phob Ganokroj Steadman Philippon Research Institute, Vail, Colorado, USA
Faculty of Medicine Siriraj Hospital, Mahidol University

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Matthew L Vopat Steadman Philippon Research Institute, Vail, Colorado, USA
The Steadman Clinic, Vail, Colorado, USA

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Joan C Rutledge Steadman Philippon Research Institute, Vail, Colorado, USA

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Kohei Yamaura Steadman Philippon Research Institute, Vail, Colorado, USA

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Sunikom Suppauksorn Institute of Orthopaedics, Lerdsin General Hospital, Bangkok, Thailand

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Peter J Millett Steadman Philippon Research Institute, Vail, Colorado, USA
The Steadman Clinic, Vail, Colorado, USA

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.10.024 ) 24. St Pierre P Millett PJ Abboud JA Cordasco FA Cuff DJ Dines DM Dornan GJ Duralde XA Galatz LM Jobin CM Consensus statement on the treatment of massive irreparable rotator cuff tears: a Delphi approach by the Neer Circle of the

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Pablo Castillón Department of Trauma and Orthopaedic Surgery, Hospital, Universitari Mútua Terrassa, Terrassa, Barcelona, Spain
Universidad Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain

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Josep Maria Muñoz Vives Department of Trauma and Orthopaedic Surgery, Hospital Althaia Manresa. Manresa, Barcelona, Spain
Department of Trauma and Orthopaedic Surgery, Hospital Nostra Senyora de Meritxell, Andorra

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Héctor José Aguado Department of Trauma and Orthopaedic Surgery, Hospital Clínico Universitario de Valladolid. Valladolid, Spain
Universidad de Valladolid, Valladolid, Spain

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Arantxa Capel Agundez Department of Trauma and Orthopaedic Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain

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Alina Ortega-Briones Department of Trauma and Orthopaedic Surgery, Hospital Clínico Universitario de Valladolid. Valladolid, Spain

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Jorge Hassan Núñez Department of Trauma and Orthopaedic Surgery, Hospital, Universitari Mútua Terrassa, Terrassa, Barcelona, Spain
Universidad Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain

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the PISCO Investigators †
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the PISCO Investigators

principles, modify them or add a different one, during a 30-day period. Step 3 (December 2021 to November 2022): Validation process. Every 4 months since December 2021, the Delphi technique was used to collect the 22 delegates’ opinions on a set of

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Antonio Cartucho Shoulder and Elbow Unit, Hospital Cuf Descobertas, Lisbon, Portugal

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expectations, pain, the clinical exam, the type and onset of the lesion, the static upward migration, and arthritic changes of the humeral head. The decision of the best surgical approach, in case of failure of conservative treatment, also depends on the

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Alan G. Fraser Department of Cardiology, University Hospital of Wales, Cardiff, UK

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Rob G.H.H. Nelissen Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands

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Per Kjærsgaard-Andersen Department of Orthopaedics, Vejle Hospital, South Danish University, Vejle, Denmark

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Piotr Szymański Centre of Postgraduate Medical Education, MSWiA Central Clinical Hospital, Warsaw, Poland

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Tom Melvin Healthcare Products Regulatory Authority, Earlsfort Terrace, Dublin 2, Ireland

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Paul Piscoi Health Technology Unit B6, Directorate General for Health (DG SANTE), European Commission, Brussels, Belgium

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On behalf of the CORE–MD Investigators (see Appendix) Alan Fraser, Piotr Szymański, Chris Gale, Aldo Maggioni, Elisabetta Zanon, Christina Dimopoulou, Cinzia Ceccarelli, Polyxeni Vairami, Anett Ruszanov, Per Kjærsgaard-Andersen, Rob Nelissen, Adrian Ott, Elizabeth Macintyre, Loredana Simulescu, Marieke Meijer, Berthold Koletzko, Sarah Wieczorek, Adamos Hadjipanayis, Stefano Del Torso, Perla Marang-van de Mheen, Lotje Hoogervorst, Ewout W. Steyerberg, Bas Penning De Vries, Peter McCulloch, Martin Landray, Daniel Prieto Alhambra, James Smith, Anne Lubbeke-Wolf, Stefan James, Sergio Buccheri, Robert Byrne, Laurna McGovern, Stephan Windecker, Andre Frenk, Georgios Siontis, Christoph Stettler, Arjola Bano, Lia Bally, Frank E. Rademakers, Jan D‘hooge, Anton Vedder, Elisabetta Biasin, Erik Kamenjasevic, Petra Schnell-Inderst, Felicitas Kühne, Ola Rolfson, Joel Jakobsson, Amanda Tornsö, Enrico G. Caiani, Lorenzo Gianquintieri, Cinzia Cappiello, Maristella Matera, Tom Melvin, Niall MacAleenan, Ria Mahon, Michèle Meagher, Gearóid McGauran, Thomas Wejs Møller, Ann-Sofie Sonne Holm-Schou, Jan Szulc, Robert E. Geertsma, Jantine W.P.M. van Baal, Joëlle M. Hoebert, Susana L.F. Cabaço, Paola Laricchiuta, Marina Torre, Filippo Boniforti, Eugenio Carrani, Stefania Ceccarelli, Claudia Wild, Sabine Ettinger, Juan Antonio Blasco Amaro, Juan Carlos Rejón Parrilla, Agnieszka Dobrzynska, David Epstein, Valentina Strammiello, Hannes Jarke, Kaisa Immonen, Françoise Schlemmer, Sabina Hoekstra, Marianna Mastroroberto, Christoph Ziskoven, Michael Hahn, Erman Melikyan, Richard Holborow, Suzanne Halliday, Alexey Shiryaev, Gero Viola, Harry van Vugt

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. Thus to obtain expert advice on appropriate methodologies and standards for clinical investigations, the European Commission published a research call in 2020 entitled ‘Developing methodological approaches for improved clinical investigation and

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Søren Overgaard Department of Orthopaedic Surgery and Traumatology, Copenhagen University Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Thomas M Grupp Aesculap AG Research & Development & Medical Scientific Affairs, Tuttlingen, Germany
Department of Orthopaedic and Trauma Surgery, Ludwig Maximilians University Munich, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Munich, Germany

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Rob GHH Nelissen Department of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands
Technical University Delft, Delft, the Netherlands

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Luca Cristofolini Department of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum - Università di Bologna, Bologna, Italy

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Anne Lübbeke Division of Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK

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Marcus Jäger Department of Orthopaedics, Trauma & Reconstructive Surgery St. Marien Hospital Mülheim an der Ruhr & Chair of Orthopaedics and Trauma Surgery University of Duisburg–Essen, Essen, Germany

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Matthias Fink TÜV Süd Product Service GmbH, Clinical Centre of Excellence, Munich Germany

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Sabine Rusch Aesculap AG Research & Development & Medical Scientific Affairs, Tuttlingen, Germany

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Hassan Achakri Zimmer Biomet, Clinical, Regulatory & Quality Affairs, Winterthur, Switzerland

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Francesco Benazzo IUSS Pavia, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy

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Dario Bergadano Medacta International SA, Medical Affairs, Castel San Pietro, Switzerland

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Georg N Duda Julius Wolff Institute and Center for Muskuloskeletal Surgery, Berlin Institute of Health at Charité Universitätsmedizin Berlin, Germany

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Christian Kaddick EndoLab Mechanical Engineering GmbH, Riedering, Germany

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Volkmar Jansson Department of Orthopaedic and Trauma Surgery, Ludwig Maximilians University Munich, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Munich, Germany

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Klaus-Peter Günther University Clinic Carl Gustav Carus, Center for Orthopaedic & Trauma Surgery, Technical University Dresden, Dresden, Germany

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clinical and pre-clinical evaluation of the innovation in terms of insufficient validation of clinical outcomes and side effects. This stresses that the new Medical Device Regulation (MDR) is warranted. Introduction of new treatment techniques, modified

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Markus Walther Schön Klinik München Harlaching – FIFA Medical Centre of Excellence, Harlachinger Straße, Munich, Germany
Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Justus Maximilian University Wuerzburg, König-Ludwig-Haus, Brettreichstraße, Würzburg, Germany
Paracelsus Medizinische Privatuniversität, Strubergasse, Salzburg, Austria
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany

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Oliver Gottschalk Schön Klinik München Harlaching – FIFA Medical Centre of Excellence, Harlachinger Straße, Munich, Germany
Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany

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Matthias Aurich Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany
Martin-Luther-University Halle-Wittenberg, Universitätsklinikum Halle (Saale), DOUW - Abteilung für Unfall- und Wiederherstellungschirurgie, Ernst-Grube-Straße, Halle, Germany
BG-Klinikum Bergmannstrost Halle, Halle, Saale, Germany

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rate of 46.2%. The authors have been reluctant to recommend this treatment concept. Gu et al. ( 71 ) reported significantly better results in patients with stage V OLT (Hepple classification, see Table 5 ( 72 )) with a modified approach. After

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Demien Broekhuis Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Rutger Tordoir Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Zoe Vallinga Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Jan Schoones Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Bart Pijls Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Rob Nelissen Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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or full surgical revision of the CTAC or associated THA components; that is, open reduction without component revision for dislocation will not classify as implant failure), functional outcome scores, surgical approach, implant manufacturer, liner

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Philippe Beaufils Department of Orthopaedics and Traumatology, Centre Hospitalier de Versailles, 78150 Le Chesnay, France

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Roland Becker Department of Orthopaedics and Traumatology, Hospital Brandenburg, Medical School Theodor Fontane, Hochstrasse 26, 14770 Brandburg/Havel, Germany

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Sebastian Kopf Center for Musculoskeletal Surgery, Charité University Medicine, Berlin, Charitéplatz 1, 10117 Berlin, Germany

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Ollivier Matthieu Department of Orthopaedics and Traumatology, Centre Hospitalier de Versailles, 78150 Le Chesnay, and Aix Marseille Univ, CNRS, ISM, Inst Movement Sci, 13000 Marseille, France

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Nicolas Pujol Department of Orthopaedics and Traumatology, Centre Hospitalier de Versailles, 78150 Le Chesnay, France

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knees, even if histological samples demonstrate some mucoid degenerative tissue. When functional treatment fails, meniscus repair can be considered. Pujol et al 33 proposed an open approach. Meniscus repair is performed with vertical sutures ( Fig

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George Mihai Avram Department of Orthopedics and Traumatology, Central Military Emergency Hospital Dr. Carol Davila, Bucharest, Romania

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Aleksandra Królikowska Physiotherapy Research Laboratory, University Centre of Physiotherapy and Rehabilitation, Faculty of Physiotherapy, Wroclaw University, Wroclaw, Poland

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Berte Bøe Division of Orthopedics Surgery, Oslo University Hospital, Norway

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Paweł Reichert Department of Orthopedics, Traumatology and Hand Surgery, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland

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Ion-Andrei Popescu Orthopedic Surgery and Sports Clinic, ORTOPEDICUM, Bucharest, Romania

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Roland Becker Center of Orthopedics and Traumatology, University Hospital Brandenburg/Havel, Brandenburg Medical School Theodor Fontane, Brandenburg a.d.H., Germany
Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Brandenburg a.d.H., Germany

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Robert Prill Center of Orthopedics and Traumatology, University Hospital Brandenburg/Havel, Brandenburg Medical School Theodor Fontane, Brandenburg a.d.H., Germany
Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Brandenburg a.d.H., Germany

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trials for shoulder disorders: a modified Delphi study . RMD Open 2016 2 e000380 . ( https://doi.org/10.1136/rmdopen-2016-000380 ) 17 Ramiro S Page MJ Whittle SL Huang H Verhagen AP Beaton DE Richards P Voshaar M Shea B van der Windt

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