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Mark Anthony Roussot Department of Trauma and Orthopaedics, University College London Hospitals, London, UK
Department of Orthopaedic Surgery, University of Cape Town, South Africa

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Georges Frederic Vles Department of Trauma and Orthopaedics, University College London Hospitals, London, UK

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Sam Oussedik Department of Trauma and Orthopaedics, University College London Hospitals, London, UK

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floor during single leg stance. 5 Insall, on the other hand, focussed on restoring neutral mechanical alignment (MA) with orthogonal femoral and tibial resections, subsequently balancing flexion and extension gaps with soft tissue releases ( Fig. 1

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Timothy Lording Melbourne Orthopaedic Group and The Alfred Hospital, Australia

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Sébastien Lustig Albert Trillat Center, Groupement Hospitalier Nord, Université Lyon 1, France

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Philippe Neyret Albert Trillat Center, Groupement Hospitalier Nord, Université Lyon 1, France

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A long-held principle in total knee arthroplasty (TKA) is that long-term survival and optimal function are dependent on achieving a post-operative leg alignment within 3° of the neutral mechanical axis. To this end, computer navigation and now

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Sohail Nisar Leeds Institute of Rheumatic and Musculoskeletal Medicine, UK
Academic Department of Trauma and Orthopaedics, LGI, University of Leeds, Leeds, UK
Leeds Teaching Hospitals Trust, UK

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Jeya Palan Leeds Teaching Hospitals Trust, UK

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Charles Rivière MSK Lab - Imperial College London, White City Campus, London, UK
The Lister Hospital, Chelsea Bridge, London, UK
Centre de l’Arthrose - Clinique du Sport, Bordeaux-Mérignac, France

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Mark Emerton Leeds Teaching Hospitals Trust, UK

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Hemant Pandit Leeds Institute of Rheumatic and Musculoskeletal Medicine, UK
Leeds Teaching Hospitals Trust, UK

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(2–3° valgus) relative to the mechanical axis of the lower limb, using a ‘systematic approach’. 5 AA aims for a neutral limb alignment with an oblique joint line relative to the mechanical axis of the limb. 6 This was thought to provide

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Nuno Marques Luís Knee and Ankle Surgery, Arthroscopy and Sports Trauma Unit; Orthopedic Center, Hospital Cuf Descobertas, Lisbon, Portugal

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Ricardo Varatojo Knee and Ankle Surgery, Arthroscopy and Sports Trauma Unit; Orthopedic Center, Hospital Cuf Descobertas, Lisbon, Portugal

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The alignment of the lower limb can be evaluated with standard radiographic techniques. However, the mechanical and anatomic axes of the lower limb are only precisely assessed if the ankle and hip positions are known. Standing views allow the

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Charles Rivière Imperial College London, UK; South West London Elective Orthopaedic Centre, UK

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Stefan Lazic South West London Elective Orthopaedic Centre, UK

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Oliver Boughton Imperial College London, UK

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Yann Wiart Theresienkrankenhauss Mannheim, Germany

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Loic Vïllet Centre de l’arthrose, Mérignac, France

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Justin Cobb Imperial College London, UK

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and other improvements such as better wear-resistance with modern polyethylene and better cementation, some authors have started to challenge the basics of the mechanical alignment (MA) technique and recently developed and tested more anatomy

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Ahmed Siddiqi Cleveland Clinic Foundation, Department of Orthopedics Cleveland, Ohio, USA

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Timothy Horan Philadelphia College of Osteopathic Medicine, Department of Orthopedics, Philadelphia, Pennsylvania, USA

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Robert M. Molloy Cleveland Clinic Foundation, Department of Orthopedics Cleveland, Ohio, USA

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Michael R. Bloomfield Cleveland Clinic Foundation, Department of Orthopedics Cleveland, Ohio, USA

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Preetesh D. Patel Cleveland Clinic Florida, Department of Orthopedics, Weston, Florida, USA

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Nicolas S. Piuzzi Cleveland Clinic Foundation, Department of Orthopedics Cleveland, Ohio, USA

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imprecise bone cuts. 28 Studies have also shown superior results with RA-TKA versus CAN-TKA, with shorter operative duration, less coronal/sagittal deviation and increased accuracy of mechanical axis alignment restoration. 16 , 29 , 30 Newer

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Geert Meermans Bravis Hospital, Roosendaal, The Netherlands

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George Grammatopoulos The Ottawa Hospital, Ottawa, Ontario, Canada

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Moritz Innmann Heidelberg University Hospital, Heidelberg, Germany

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David Beverland Belfast Health and Social Care Trust, Belfast, UK

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on the presumption that it is easier for surgeons to evaluate a 90° angle than a 45° angle. These mechanical alignment guides are limited in that they can only achieve one target angle and lack accuracy ( 16 , 17 , 71 ). When operating with the

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Theofilos Karachalios School of Health Sciences, Faculty of Medicine, University of Thessalia, Greece
Orthopaedic Department, University General Hospital of Larissa, Greece

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George A. Komnos Orthopaedic Department, University General Hospital of Larissa, Greece

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method of osteotomy. 21 , 22 Alignment should be considered in three different planes (frontal, sagittal and transverse) and a surgeon should be able to recognize the lower limb mechanical axis, femoral and tibia bone anatomical and mechanical axes

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Charles Rivière Clinique du Sport, Bordeaux-Mérignac, France
Personalized Arthroplasty Society, Atlanta, Georgia, USA

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William Jackson Personalized Arthroplasty Society, Atlanta, Georgia, USA
Nuffield Orthopaedic Centre, Headington, Oxford, UK

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Loïc Villet Clinique du Sport, Bordeaux-Mérignac, France
Personalized Arthroplasty Society, Atlanta, Georgia, USA

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Sivan Sivaloganathan Personalized Arthroplasty Society, Atlanta, Georgia, USA
South-West London Elective Orthopaedic Centre, Epsom, UK

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Yaron Barziv Personalized Arthroplasty Society, Atlanta, Georgia, USA
Shamir Medical Center, Zriffin, Israel

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Pascal-André Vendittoli Personalized Arthroplasty Society, Atlanta, Georgia, USA
Département de Chirurgie, Université de Montréal, Hôpital Maisonneuve-Rosemont, Montréal, Québec, Canada

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reduces the extent of soft tissue releases compared to more traditional mechanical alignment surgery. 10 , 11 In a study assessing 4884 lower limb computerized tomography (CT) scans of patients scheduled for TKA (performed with patient

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Aline Van Oevelen Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium
Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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Arne Burssens Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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Nicola Krähenbühl Department of Orthopaedics, University Hospital Basel, Basel, Switzerland

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Alexej Barg Department of Orthopaedics and Trauma, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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Bernhard Devos Bevernage Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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Emmanuel Audenaert Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium
Department of Electromechanics, InViLab research group, University of Antwerp, Antwerp, Belgium
Department of Trauma and Orthopedics, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Beat Hintermann Department of Orthopaedics, Kantonsspital Baselland, Liestal, Switzerland

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Jan Victor Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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) Intraarticular ankle pressure minimally changed for a 5° change in the mechanical alignment ( P > 0.05). For corrections of 10° and 15°, mean contact pressures decreases respectively by 14% ( P < 0.05) and 17% ( P < 0.05). The mean contact surface area

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