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Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark
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Introduction Lower extremity amputation bears a high risk for post-surgical wound infections ( 1 ). Multi-morbid patients with diabetes-induced peripheral arterial disease represent the main subjects of major lower limb amputations ( 2 ). A
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Introduction Major amputations of the lower extremity may be required after trauma and variety of underlying diseases such as peripheral vascular disease (PVD), diabetes, and malignancies. The goal of any major amputation is an optimal
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Introduction The dawn of extremity bone sarcoma management was dominated by amputation as a standard of surgical treatment. Although some attempts were made to perform limb-sparing procedures, by carrying out segmental resection and
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results of all studies. More recent and higher quality data which formed the major pool of cases and compared with controls have shown more positive consistency and direction of effect towards better quality of life after amputation. 25 , 26
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Biomechatronics Group, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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congenital musculoskeletal anomalies. 1 , 14 The main objective of the present review is to identify all major studies dealing with amputation surgery and prosthetic technologies published between 1 January 2014 and 1 October 2019. The specific focus was
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major threats relating to DFU. 1 , 3 , 10 Eradication of the infection is difficult and recurrences are common, leading to purulent ulcers, functional distortion of the foot and the need for amputation. 9 The lifetime risk of diabetic patients
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these misdiagnosed tumours is the increasing rate of amputation or local recurrences in the involved patients. After the age of 40 years, chondrosarcoma is the most usual malignant tumour of the foot. In bone tumours such as osteosarcoma or Ewing
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However, the results of a meta-analysis obtained from pooled data of five trials with 312 patients indicated that there was no significant difference in terms of major amputation rate with HBOT. 49 Nonetheless, a current review strongly emphasized the
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, especially in cases where major resections or adjuvant treatments are to be proposed. Although most sarcoma treatment centers use MRI to detect local recurrences, it is necessary to confirm the histopathological type before performing surgical resection
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approach has helped to improve the quality of diabetic foot care as well as to reduce the rate of major amputations. 25 , 26 Role of diabetic MDT or foot care teams The National Institute for Health and Care Excellence (NICE) has issued guidance