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Frédéric Vauclair Department of Orthopaedics and Traumatology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

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Patrick Goetti Department of Orthopaedics and Traumatology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

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Ngoc Tram V. Nguyen Mayo Clinic, Rochester, Minnesota, USA

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Joaquin Sanchez-Sotelo Mayo Clinic, Rochester, Minnesota, USA

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injury and the quality of the initial fixation attempt. Nonunion complicating a well-performed internal fixation should raise concerns regarding infection, lack of compliance, malnutrition, and other comorbidities. However, poor quality of fixation is the

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Elena Gálvez-Sirvent Department of Orthopaedic Surgery, “Infanta Elena” University Hospital, Valdemoro, Madrid, Spain
Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain

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Aitor Ibarzábal-Gil Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain

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E Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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plateau fractures treated by open reduction and internal fixation; seven of eight (87.5%) knees became infected ( 54 ). In 2004, Barei et al . reported an 8.4% rate of deep wound infections. Of the infected patients, 3.6% had associated septic arthritis

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Abdel Rahim Elniel Leeds Teaching Hospitals Trust, UK

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Peter V. Giannoudis Academic Department of Trauma and Orthopaedics, Leeds Teaching Hospitals, University of Leeds, UK; NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, UK

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definitive management is no longer a mainstay in management. A meta-analysis comparing the management of open tibial fractures showed no difference in the rate of nonunion and infection with external fixation when compared with internal fixation methods

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Horacio Caviglia Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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Adrian Mejail Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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Maria Eulalia Landro Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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Nosratolah Vatani Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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anatomical reduction and internal fixation of fractures. 2 The objective of surgery is to achieve exact reduction to restore joint congruence, to adequately fix internal bone fragments, avoid displacement of the fracture and allow rapid rehabilitation

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Duy Nguyen Anh Tran The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Bao Tu Thai Nguyen The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Tan Thanh Nguyen Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Yu-Pin Chen Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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Yi-Jie Kuo Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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exclude open fractures, a significant confounder in wound infections post open reduction and internal fixation (ORIF) ( 27 , 28 , 29 , 30 ). Addressing this research gap, our comprehensive meta-analysis examines the effect of smoking on SSI incidence

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Ahmed Fikry Elmenshawy Department of Orthopaedic Surgery, RWTH Aachen University, Aachen, Germany

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Khaled Hamed Salem Department of Orthopaedic Surgery, RWTH Aachen University, Aachen, Germany
Department of Orthopaedic Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt

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include a wide variety of internal fixation methods, hemiarthroplasty or total hip replacement. The case for arthroplasty was strengthened by the use of bone cement that allows early mobilization of the fractured, elderly and morbid patients. The aims of

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Victor Lu School of Clinical Medicine, University of Cambridge, Cambridge, UK

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Maria Tennyson Department of Trauma and Orthopaedics, Addenbrooke’s Hospital, Cambridge, UK

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Andrew Zhou School of Clinical Medicine, University of Cambridge, Cambridge, UK

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Ravi Patel Department of Trauma and Orthopaedics, Shrewsbury and Telford Hospital NHS Trust, UK

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Mary D Fortune Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

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Azeem Thahir Department of Trauma and Orthopaedics, Addenbrooke’s Hospital, Cambridge, UK

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Matija Krkovic Department of Trauma and Orthopaedics, Addenbrooke’s Hospital, Cambridge, UK

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patients over 55 ( 6 ), open reduction internal fixation (ORIF) have not produced satisfactory outcomes in some studies. Litchfield reported a 22.6% non-union rate (7/31) ( 7 ), whilst Beauchamp et al. reported a total complication rate of 50.1% and an

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Ting-Yu Tu Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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Chun-Yu Chen Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan
Department of Occupational Therapy, Shu-Zen Junior College of Medicine and Management, Kaohsiung City, Taiwan
Department of Biomedical Engineering, I-Shou University, Kaohsiung City, Taiwan

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Pei-Chin Lin Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
Department of Pharmacy, School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan

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Chih-Yang Hsu Department of Internal Medicine, Division of Nephrology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

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Kai-Cheng Lin Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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Review and Meta-analysis (PRISMA) guidelines. PubMed, Cochrane, Embase, and Scopus databases were searched up to June 18, 2021, using the following search terms: ederly, acetabular fracture, replacement, and open reduction and internal fixation (ORIF

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Nikolaos Gougoulias Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Hesham Oshba Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Apostolos Dimitroulias Jacobi Medical Center – Trauma Unit – Bronx, New York, USA

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Anthony Sakellariou Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Alexander Wee Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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and ‘minimal’ internal fixation (a, b), complicated by joint destruction due to Charcot neuroarthropathy, without signs of infection. It was salvaged with ankle arthrodesis using a rigid fixation construct (plate with locking screws, augmented by

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Sylvain Steinmetz Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Diane Wernly Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Kevin Moerenhout Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Andrej Trampuz Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery (CMSC), Berlin, Germany

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Olivier Borens Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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obtaining optimal restitution of the function. Definitive and immediate treatment of the infection is not always the priority. Bone healing can be the primary objective, as the internal fixation device can be retrieved once consolidation is obtained

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