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Martin McNally The Oxford Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Geertje Govaert Department of Trauma Surgery, University of Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands

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Maria Dudareva The Oxford Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Mario Morgenstern Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium

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healthcare providers and social services over a prolonged period. 2 , 3 It is even more stressful for patients if the diagnosis of an infection is delayed or missed. Failure to begin treatment promptly may convert a simple early fracture infection into a

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AliSina Shahi The Rothman Institute at Thomas Jefferson University, Philadelphia, USA

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Javad Parvizi The Rothman Institute at Thomas Jefferson University, Philadelphia, USA

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critical for the surgeon to distinguish between septic and aseptic failure, as the treatment protocol for PJI mandates specific surgical strategies that aim to eliminate the infecting microorganism(s). 5 - 8 Diagnosis of PJI is challenging as

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Martin McNally The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Irene Sigmund The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK
Department of Orthopaedics and Trauma Surgery, Medical University of Vienna, Austria

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Andrew Hotchen The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Ricardo Sousa Porto Bone and Joint Infection Group (GRIP), Department of Orthopaedics, Centro Hospitalar Universitario Santo António and CUF-Hospitais e Clinicas, Portugal

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vary in the degree of their inflammatory response, making the use of serum biomarkers more challenging for diagnosis ( 5 , 6 ). The difficulty in diagnosis is further complicated by the presence of culture-negative infection which may be present in

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Sohail Yousaf Kingston Hospital NHS Foundation Trust, UK
University of Brighton, UK

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Edward J.C. Dawe Western Sussex Hospitals NHS Foundation Trust, UK
Brighton and Sussex Medical Schools, UK

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Alan Saleh Kingston Hospital NHS Foundation Trust, UK

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Ian R. Gill Kingston Hospital NHS Foundation Trust, UK

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Alex Wee Frimley Health NHS Foundation Trust, UK

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loss of its protective sensations. Early recognition of acute Charcot foot in diabetics is a diagnostic challenge as the clinical suspicion even in high risk patients is often low, and the consequences of a missed diagnosis can be devastating. This

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Andrea Angelini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Nicolò Mosele Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Elisa Pagliarini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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epidemiologic feature is the age. GSD can be diagnosed at any age, but it exhibits a clear preference for a young patient; it affects patients younger than 40 years of age with an average age at diagnosis of 25 years of age ( 5 , 9 , 10 , 11 , 12 , 13 , 14

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Jean-Charles Le Huec Polyclinique Bordeaux Nord Aquitaine, Bordeaux Univ, 33 300 Bordeaux, France

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Stephane Bourret Polyclinique Bordeaux Nord Aquitaine, Bordeaux Univ, 33 300 Bordeaux, France

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Wendy Thompson Polyclinique Bordeaux Nord Aquitaine, Bordeaux Univ, 33 300 Bordeaux, France

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Christian Daulouede Polyclinique Bordeaux Nord Aquitaine, Bordeaux Univ, 33 300 Bordeaux, France

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Thibault Cloché Polyclinique Bordeaux Nord Aquitaine, Bordeaux Univ, 33 300 Bordeaux, France

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weight of the body tends to push the sacrum downwards, which leads to an automatic locking effect. Diagnosis of sacro-iliac micro-traumatic pain After elimination of inflammatory diseases, ankylosing spondylitis, infections and tumours by clinical

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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Inmaculada Moracia-Ochagavía Department of Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain

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diagnosis. The dorsiflexion-eversion test is performed by maximal passive dorsiflexion and eversion of the foot while dorsiflexing the metatarsophalangeal joints. 20 , 27 In an analysis of 44 feet diagnosed with TTS using electrodiagnostic testing

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Jorge de-las-Heras Romero Department of Orthopaedics and Traumatology, University General Hospital Reina Sofía, Avda Intendente Jorge Palacios 1, Murcia 30003, Spain

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Ana María Lledó Alvarez Regional Statistical Center, Treasury and public administration council, Murcia, Spain

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Fernando Moreno Sanchez Department of Orthopaedics and Traumatology, University General Hospital Reina Sofía, Murcia, Spain

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Alejandro Perez Garcia Department of Orthopaedics and Traumatology, University General Hospital Reina Sofía, Murcia, Spain

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Pedro Antonio Garcia Porcel Department of Orthopaedics and Traumatology, University General Hospital Reina Sofía, Murcia, Spain

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Raul Valverde Sarabia Department of Orthopaedics and Traumatology, University General Hospital Reina Sofía, Murcia, Spain

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Marina Hernandez Torralba Department of Orthopaedics and Traumatology, University General Hospital Reina Sofía, Murcia, Spain

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. 5 , 6 However, recent studies show that its incidence is much higher, in the range of 17% to 74% of all sports injuries of the ankle, due in part to the improvement in the diagnosis and understanding of the mechanisms of production of these

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E. Mascard Necker University Hospital, 75015 Paris, France.

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N. Gaspar Department of Pediatrics, Institute Gustave Roussy, 94805 Villejuif, France

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L. Brugières Department of Pediatrics, Institute Gustave Roussy, 94805 Villejuif, France

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C. Glorion Orthopedic Surgery Department, Necker University Hospital, 149 rue de Sèvres, 75015 Paris, France

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S. Pannier Orthopedic Surgery Department, Necker University Hospital, 149 rue de Sèvres, 75015 Paris, France

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A. Gomez-Brouchet Laboratoire d'anatomie et cytologie pathologiques, Institut Universitaire du Cancer de Toulouse- Oncopole, 1 avenue Irène Joliot-Curie. 31059 Toulouse Cedex 9, France

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followed up in dermatology departments. Diagnosis of bone and soft-tissue foot tumours is often delayed and many malignant conditions are referred to specialised sarcoma teams after an initial inappropriate procedure. 4 - 6 The adverse effect of

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Elizabeth K Tissingh The Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK
King’s Global Health Partnerships, School of Life Course and Population Sciences, King’s College London, London, UK

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Leonard Marais Department of Orthopaedic Surgery, School of Clinical Medicine, University of KwaZulu-Natal, KwaZulu-Natal, South Africa

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Antonio Loro Comprehensive Rehabilitation Services for People with Disability in Uganda (CoRSU) Hospital, Kisubi, Uganda

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Deepa Bose University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Nilo T Paner Department of Orthopaedics, University of the Philippines, Philippine General Hospital Manila, The Phillipines

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Jamie Ferguson The Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK
Department of Orthopaedics, University of the Philippines, Philippine General Hospital Manila, The Phillipines

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Mario Morgensten Centre for Musculoskeletal Infections, Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland

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Martin McNally The Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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.0–1188.7) to 1574 (95% CI: 1285.1–1915.1) per 100 000 person-years, across 14 countries ( 11 ). An epidemiological study in Rwanda carried out a national household survey and found a musculoskeletal impairment prevalence of 5.2%. Of these, 4% had a diagnosis of

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