Wen-xi Sun
Wen-xi Sun
State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
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Wei-qiang Huang
Wei-qiang Huang
State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
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Hua-yang Li
Hua-yang Li
State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
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Hong-shen Wang
Hong-shen Wang
State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
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Sheng-li Guo
Sheng-li Guo
State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
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Jie Dong
Jie Dong
Huizhou Hospital of Guangzhou University of Chinese Medicine, Huizhou, China
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Bo-lai Chen
Bo-lai Chen
State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
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Yong-peng Lin
Yong-peng Lin
State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China
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.76%) Cerebrospinal fluid leak 1 (0.13%) 3 (0.38%) Decreased muscle strength 1 (0.13%) 1 (0.13%) Dural injury 0 1 (0.13%) Total 38 (4.83%) 119 (14.97%) FH, freehand; RA, robot assisted. Clinical efficacy
Guo-xu Zhang
Guo-xu Zhang
Guangzhou University of Chinese Medicine, Guangzhou, China
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Ji Li
Ji Li
Guangzhou University of Chinese Medicine, Guangzhou, China
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Qi-jun Xie
Qi-jun Xie
Guangzhou University of Chinese Medicine, Guangzhou, China
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Mei-ren Zhang
Mei-ren Zhang
Guangdong Hospital of Traditional Chinese Medicine, Guangzhou, China
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Kui Zhao
Kui Zhao
Guangdong Hospital of Traditional Chinese Medicine, Guangzhou, China
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Hai-yun Chen
Hai-yun Chen
Guangdong Hospital of Traditional Chinese Medicine, Guangzhou, China
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primarily employs meta-analysis to compare the clinical efficacy and postoperative complications of two surgical methods for treating comminuted fractures of the distal femur. Materials and methods This meta-analysis was performed according to the
Wen-xi Sun
Wen-xi Sun
Guangzhou University of Chinese Medicine, Guangzhou, China
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Hao-nan Liu
Hao-nan Liu
Guangzhou University of Chinese Medicine, Guangzhou, China
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Meng-tong Chen
Meng-tong Chen
Guangzhou University of Chinese Medicine, Guangzhou, China
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Yong-peng Lin
Yong-peng Lin
Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China
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Hong-shen Wang
Hong-shen Wang
Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China
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Bo-lai Chen
Bo-lai Chen
Guangzhou University of Chinese Medicine, Guangzhou, China
Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China
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Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China
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increasingly recognized by orthopaedic surgeons. They have gradually become widely used clinical procedures. However, there is still debate as to which of these two techniques is more advantageous ( 6 ). A meta-analysis of the clinical efficacy and safety of
Tristan Ferry
Tristan Ferry
Service de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)
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Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)
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Jolien Onsea
Jolien Onsea
Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium
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Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium
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Tiphaine Roussel-Gaillard
Tiphaine Roussel-Gaillard
Institut des Agents Infectieux, Centre de Biologie et de Pathologie du Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
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Cécile Batailler
Cécile Batailler
Service de Chirurgie Orthopédique et de Médecine du Sport, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
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Thomas Fintan Moriarty
Thomas Fintan Moriarty
AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, Switzerland
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Willem-Jan Metsemakers
Willem-Jan Metsemakers
Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium
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Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium
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, administration protocols and phage selection. Future perspectives entail addressing regulatory barriers, standardising treatment protocols and conducting high-quality clinical trials to establish phage therapy’s efficacy for the treatment of MSIs. ICMJE
Hsiao-Yi Cheng
Hsiao-Yi Cheng
Department of Primary Care Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Chun-Wei Liang
Chun-Wei Liang
School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Primary Care Medicine, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
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Department of Primary Care Medicine, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
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Yu-Hao Lee
Yu-Hao Lee
Department of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Timporn Vitoonpong
Timporn Vitoonpong
Department of Rehabilitation, King Chulalongkorn Memorial Hospital, Bankok, Thailand
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Chun-De Liao
Chun-De Liao
Department of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
Master’s Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan
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Master’s Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan
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Shih-Wei Huang
Shih-Wei Huang
Department of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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corticosteroids exhibited an efficacy similar to that of exercise alone. We found no clinical trials on the effects of stromal vascular fractions combined with exercise and thus could not evaluate the effects of stromal vascular fractions in the present study
Alan G. Fraser
Alan G. Fraser
Department of Cardiology, University Hospital of Wales, Cardiff, UK
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Rob G.H.H. Nelissen
Rob G.H.H. Nelissen
Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands
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Per Kjærsgaard-Andersen
Per Kjærsgaard-Andersen
Department of Orthopaedics, Vejle Hospital, South Danish University, Vejle, Denmark
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Piotr Szymański
Piotr Szymański
Centre of Postgraduate Medical Education, MSWiA Central Clinical Hospital, Warsaw, Poland
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Tom Melvin
Tom Melvin
Healthcare Products Regulatory Authority, Earlsfort Terrace, Dublin 2, Ireland
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Paul Piscoi
Paul Piscoi
Health Technology Unit B6, Directorate General for Health (DG SANTE), European Commission, Brussels, Belgium
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On behalf of the CORE–MD Investigators (see Appendix)
On behalf of the CORE–MD Investigators (see Appendix)
Alan Fraser, Piotr Szymański, Chris Gale, Aldo Maggioni, Elisabetta Zanon, Christina Dimopoulou, Cinzia Ceccarelli, Polyxeni Vairami, Anett Ruszanov, Per Kjærsgaard-Andersen, Rob Nelissen, Adrian Ott, Elizabeth Macintyre, Loredana Simulescu, Marieke Meijer, Berthold Koletzko, Sarah Wieczorek, Adamos Hadjipanayis, Stefano Del Torso, Perla Marang-van de Mheen, Lotje Hoogervorst, Ewout W. Steyerberg, Bas Penning De Vries, Peter McCulloch, Martin Landray, Daniel Prieto Alhambra, James Smith, Anne Lubbeke-Wolf, Stefan James, Sergio Buccheri, Robert Byrne, Laurna McGovern, Stephan Windecker, Andre Frenk, Georgios Siontis, Christoph Stettler, Arjola Bano, Lia Bally, Frank E. Rademakers, Jan D‘hooge, Anton Vedder, Elisabetta Biasin, Erik Kamenjasevic, Petra Schnell-Inderst, Felicitas Kühne, Ola Rolfson, Joel Jakobsson, Amanda Tornsö, Enrico G. Caiani, Lorenzo Gianquintieri, Cinzia Cappiello, Maristella Matera, Tom Melvin, Niall MacAleenan, Ria Mahon, Michèle Meagher, Gearóid McGauran, Thomas Wejs Møller, Ann-Sofie Sonne Holm-Schou, Jan Szulc, Robert E. Geertsma, Jantine W.P.M. van Baal, Joëlle M. Hoebert, Susana L.F. Cabaço, Paola Laricchiuta, Marina Torre, Filippo Boniforti, Eugenio Carrani, Stefania Ceccarelli, Claudia Wild, Sabine Ettinger, Juan Antonio Blasco Amaro, Juan Carlos Rejón Parrilla, Agnieszka Dobrzynska, David Epstein, Valentina Strammiello, Hannes Jarke, Kaisa Immonen, Françoise Schlemmer, Sabina Hoekstra, Marianna Mastroroberto, Christoph Ziskoven, Michael Hahn, Erman Melikyan, Richard Holborow, Suzanne Halliday, Alexey Shiryaev, Gero Viola, Harry van Vugt
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clinical evidence generation after market access Methods used to generate clinical evidence for high-risk medical devices Methods used to evaluate the clinical safety and efficacy of devices and to monitor their performance should be
Enrique Gómez-Barrena
Enrique Gómez-Barrena
Servicio de Cirugía Ortopédica y Traumatología, Hospital La Paz-IdiPAZ, Universidad Autónoma de Madrid, Madrid, Spain
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Norma G. Padilla-Eguiluz
Norma G. Padilla-Eguiluz
Servicio de Cirugía Ortopédica y Traumatología, Hospital La Paz-IdiPAZ, Universidad Autónoma de Madrid, Madrid, Spain
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Philippe Rosset
Philippe Rosset
Service de Chirurgie Orthopédique et Traumatologie, CHU Tours, Université de Tours, Tours, France
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painful delayed union as a non-union. 2 However, and despite the general belief, the most commonly used definition of a non-union in clinical trials today was proposed by the Food and Drug Administration (FDA): ‘A non-union occurs when fracture
Thomas Collins
Thomas Collins
Trauma & Orthopaedics, Wythenshawe Hospital, Wythenshawe, UK
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Dinesh Alexander
Dinesh Alexander
Trauma & Orthopaedics, Salford Royal Hospital, Salford, UK
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Bilal Barkatali
Bilal Barkatali
Trauma & Orthopaedics, Salford Royal Hospital, Salford, UK
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compared to corticosteroid, were those documenting L-PRP was used. Systematic review and meta-analyses of studies assessing PRP efficacy in Achilles tendinopathy 53 showed that PRP conferred no clinical benefit when compared to saline placebo or an
Abdus S. Burahee
Abdus S. Burahee
The Peripheral Nerve Injury Service, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Andrew D. Sanders
Andrew D. Sanders
The Peripheral Nerve Injury Service, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Colin Shirley
Colin Shirley
The Peripheral Nerve Injury Service, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Dominic M. Power
Dominic M. Power
The Peripheral Nerve Injury Service, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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CuTS has not been demonstrated. Different techniques are selected for different clinical situations with SD being the most common procedure due to its good efficacy and low complication rate. 35 – 38 Simple decompression SD is performed with a
Silvia Valisena
Silvia Valisena
Department of Orthopaedics, University Hospitals of Geneva, Genève, Switzerland
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Benjamin Azogui
Benjamin Azogui
Department of Orthopaedics, Hôpital Lariboisière, Paris, France
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Rémy S Nizard
Rémy S Nizard
Department of Orthopaedics, Hôpital Lariboisière, Paris, France
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Philippe M Tscholl
Philippe M Tscholl
Department of Orthopaedics, University Hospitals of Geneva, Genève, Switzerland
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Etienne Cavaignac
Etienne Cavaignac
Department of Orthopaedics, Hôpital Pierre Paul Riquet, CHU Toulouse, Toulouse, France
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Pierre-Alban Bouché
Pierre-Alban Bouché
Department of Orthopaedics, Hôpital Lariboisière, Paris, France
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Didier Hannouche
Didier Hannouche
Department of Orthopaedics, University Hospitals of Geneva, Genève, Switzerland
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which treatment has the best efficacy and safety profile since they compare only two techniques each ( 20 ). This necessitates the summary of evidence with network meta-analyses (NMA) that, by allowing the comparison of multiple treatments, bypass the
