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James R. Berstock University of British Colombia Department of Orthopaedics, Gordon & Leslie Diamond Health Care Centre, Vancouver, British Columbia, Canada

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Michael R. Whitehouse Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Southmead Hospital, Bristol, UK
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, UK

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and thereby inform clinical practice. They are increasingly seen as providing the most reliable conclusions about treatments. Another important role of systematic reviews is to highlight where no reliable evidence exists (for example only level 3 or 4

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.4.180049
Volume/Issue:
Volume 4: Issue 5
Open access
Tristan Ferry Service de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)

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Jolien Onsea Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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Tiphaine Roussel-Gaillard Institut des Agents Infectieux, Centre de Biologie et de Pathologie du Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Cécile Batailler Service de Chirurgie Orthopédique et de Médecine du Sport, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Thomas Fintan Moriarty AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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prosthesis, resection prosthesis, prosthesis–arthrodesis and total femur) ( 3 ). For patients with PJI, it is necessary to avoid dead-end clinical situations, as transfemoral amputation or hip disarticulation are associated with a catastrophic functional

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1530/EOR-24-0042
Volume/Issue:
Volume 9: Issue 5
Open access
Anne Lübbeke Division of Orthopaedic Surgery & Traumatology, Geneva University Hospitals and University of Geneva, Switzerland
Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK

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Christophe Combescure Division of Clinical Epidemiology, Geneva University Hospitals and University of Geneva, Switzerland

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Christophe Barea Division of Orthopaedic Surgery & Traumatology, Geneva University Hospitals and University of Geneva, Switzerland

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Amanda Inez Gonzalez Division of Orthopaedic Surgery & Traumatology, Geneva University Hospitals and University of Geneva, Switzerland

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Keith Tucker Chair Orthopaedic Data Evaluation Panel, UK

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Per Kjærsgaard-Andersen Center for Adult Hip and Knee Reconstruction, Department of Orthopaedics, South Danish University, Vejle Hospital, Denmark

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Tom Melvin School of Medicine, Trinity College Dublin, Ireland

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Alan G Fraser Department of Cardiology, University Hospital of Wales, Cardiff, UK

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Rob Nelissen Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands

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James A Smith Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK
National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK

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Introduction Little is known about the clinical evidence used to establish the safety and performance of medical devices before and after market access in Europe. Unlike medicines in Europe and in the USA, and medical devices that are subject

Article Type:
Systematic Review
Category:
General Orthopaedics
DOI:
https://doi.org/10.1530/EOR-23-0024
Volume/Issue:
Volume 8: Issue 11
Open access
Markus Walther Schön Klinik München Harlaching – FIFA Medical Centre of Excellence, Harlachinger Straße, Munich, Germany
Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Justus Maximilian University Wuerzburg, König-Ludwig-Haus, Brettreichstraße, Würzburg, Germany
Paracelsus Medizinische Privatuniversität, Strubergasse, Salzburg, Austria
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany

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Oliver Gottschalk Schön Klinik München Harlaching – FIFA Medical Centre of Excellence, Harlachinger Straße, Munich, Germany
Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany

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Matthias Aurich Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany
Martin-Luther-University Halle-Wittenberg, Universitätsklinikum Halle (Saale), DOUW - Abteilung für Unfall- und Wiederherstellungschirurgie, Ernst-Grube-Straße, Halle, Germany
BG-Klinikum Bergmannstrost Halle, Halle, Saale, Germany

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Introduction Osteochondral lesions of the talus (OLT) affect the talar dome with varying involvement of the articular cartilage and subchondral bone. In 2017, the working group ‘Clinical Tissue Regeneration’ of the German Society of

Article Type:
Review Article
Category:
Trauma
DOI:
https://doi.org/10.1530/EOR-23-0075
Volume/Issue:
Volume 9: Issue 3
Open access
Alan G. Fraser Department of Cardiology, University Hospital of Wales, Cardiff, UK

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Rob G.H.H. Nelissen Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands

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Per Kjærsgaard-Andersen Department of Orthopaedics, Vejle Hospital, South Danish University, Vejle, Denmark

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Piotr Szymański Centre of Postgraduate Medical Education, MSWiA Central Clinical Hospital, Warsaw, Poland

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Tom Melvin Healthcare Products Regulatory Authority, Earlsfort Terrace, Dublin 2, Ireland

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Paul Piscoi Health Technology Unit B6, Directorate General for Health (DG SANTE), European Commission, Brussels, Belgium

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On behalf of the CORE–MD Investigators (see Appendix) Alan Fraser, Piotr Szymański, Chris Gale, Aldo Maggioni, Elisabetta Zanon, Christina Dimopoulou, Cinzia Ceccarelli, Polyxeni Vairami, Anett Ruszanov, Per Kjærsgaard-Andersen, Rob Nelissen, Adrian Ott, Elizabeth Macintyre, Loredana Simulescu, Marieke Meijer, Berthold Koletzko, Sarah Wieczorek, Adamos Hadjipanayis, Stefano Del Torso, Perla Marang-van de Mheen, Lotje Hoogervorst, Ewout W. Steyerberg, Bas Penning De Vries, Peter McCulloch, Martin Landray, Daniel Prieto Alhambra, James Smith, Anne Lubbeke-Wolf, Stefan James, Sergio Buccheri, Robert Byrne, Laurna McGovern, Stephan Windecker, Andre Frenk, Georgios Siontis, Christoph Stettler, Arjola Bano, Lia Bally, Frank E. Rademakers, Jan D‘hooge, Anton Vedder, Elisabetta Biasin, Erik Kamenjasevic, Petra Schnell-Inderst, Felicitas Kühne, Ola Rolfson, Joel Jakobsson, Amanda Tornsö, Enrico G. Caiani, Lorenzo Gianquintieri, Cinzia Cappiello, Maristella Matera, Tom Melvin, Niall MacAleenan, Ria Mahon, Michèle Meagher, Gearóid McGauran, Thomas Wejs Møller, Ann-Sofie Sonne Holm-Schou, Jan Szulc, Robert E. Geertsma, Jantine W.P.M. van Baal, Joëlle M. Hoebert, Susana L.F. Cabaço, Paola Laricchiuta, Marina Torre, Filippo Boniforti, Eugenio Carrani, Stefania Ceccarelli, Claudia Wild, Sabine Ettinger, Juan Antonio Blasco Amaro, Juan Carlos Rejón Parrilla, Agnieszka Dobrzynska, David Epstein, Valentina Strammiello, Hannes Jarke, Kaisa Immonen, Françoise Schlemmer, Sabina Hoekstra, Marianna Mastroroberto, Christoph Ziskoven, Michael Hahn, Erman Melikyan, Richard Holborow, Suzanne Halliday, Alexey Shiryaev, Gero Viola, Harry van Vugt

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scientific department with medical expertise in each major clinical field. High-risk implantable medical devices are essential for clinical care. Scrutiny of clinical evidence before their market access is also essential. Uncertainty about the standards

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.6.210081
Volume/Issue:
Volume 6: Issue 10
Open access
Laura Stiegel Cleveland Clinic Department of Orthopaedic Surgery, Cleveland, Ohio, USA

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Alison K. Klika Cleveland Clinic Department of Orthopaedic Surgery, Cleveland, Ohio, USA

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Carlos A. Higuera Cleveland Clinic Department of Orthopaedic Surgery, Weston, Florida, USA

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Wael K.Barsoum Cleveland Clinic Department of Orthopaedic Surgery, Weston, Florida, USA

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Nicolas S. Piuzzi Cleveland Clinic Department of Orthopaedic Surgery, Cleveland, Ohio, USA

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understand the organizational network of a research team. Fig. 1 offers clinicians a brief overview of how a team network works through dynamic interaction. Fig. 1 Network of a team. Note . CRA, clinical research associate; CRO, contract research

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.6.200058
Volume/Issue:
Volume 6: Issue 4
Open access
Przemysław Lubiatowski Sport Trauma and Biomechanics Unit, University of Medical Sciences, Poznań, Poland
Rehasport Clinic, Poznań, Poland
Department of Traumatology, Orthopaedics and Hand Surgery, University of Medical Sciences, Poznań, Poland

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Joanna Wałecka Sport Trauma and Biomechanics Unit, University of Medical Sciences, Poznań, Poland
Rehasport Clinic, Poznań, Poland
Department of Traumatology, Orthopaedics and Hand Surgery, University of Medical Sciences, Poznań, Poland

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Marcin Dzianach Rehasport Clinic, Poznań, Poland

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Jakub Stefaniak Sport Trauma and Biomechanics Unit, University of Medical Sciences, Poznań, Poland
Rehasport Clinic, Poznań, Poland
Department of Traumatology, Orthopaedics and Hand Surgery, University of Medical Sciences, Poznań, Poland

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Leszek Romanowski Department of Traumatology, Orthopaedics and Hand Surgery, University of Medical Sciences, Poznań, Poland

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Definition, clinical relevance, clinical picture, diagnosis and the treatment of the elbow synovial plica syndrome have brought some confusion. The literature in the scope of medical journals is rare. Even the terminology has not been uniformed

Article Type:
Review Article
Category:
Shoulder & Elbow
DOI:
https://doi.org/10.1302/2058-5241.5.200027
Volume/Issue:
Volume 5: Issue 9
Open access
Ferdinando Auricchio Department of Civil Engineering and Architecture, University of Pavia, Italy

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Stefania Marconi Department of Civil Engineering and Architecture, University of Pavia, Italy

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clinical data. The advent of minimally-invasive techniques such as laparoscopic surgery, or - more recently - robotics, have completely changed surgeons’ approach to intervention. There is a need for greater understanding of the specific anatomy in order

Article Type:
Research Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.1.000012
Volume/Issue:
Volume 1: Issue 5
Open access
Eduard Alentorn-Geli Mayo Clinic, Rochester, Minnesota, USA

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Andrew T. Assenmacher Mayo Clinic, Rochester, Minnesota, USA

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Joaquín Sánchez-Sotelo Mayo Clinic, Rochester, Minnesota, USA

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methods. 1 While some individuals may maintain reasonable function after non-operative treatment of a ruptured DBT, biomechanical and clinical studies suggest that most individuals benefit from surficial repair or reconstruction. 2 Over the last

Article Type:
Review Article
Category:
Shoulder & Elbow
DOI:
https://doi.org/10.1302/2058-5241.1.000053
Volume/Issue:
Volume 1: Issue 9
Open access
Thomas M Grupp Aesculap AG, Research & Development & Medical Scientific Affairs, Tuttlingen, Germany
Ludwig Maximilians University Munich, Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Munich, Germany

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Sabine Rusch Aesculap AG, Research & Development & Medical Scientific Affairs, Tuttlingen, Germany

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Philippe Massin CMC Ambroise-Paré-Hartmann, Neuilly-sur-Seine, France

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Ashley Blom National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, UK
Translational Health Sciences, Bristol Medical School, Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK

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Eduardo Garcia-Rey Hôpital Universitario La Paz-Idi Paz, Madrid, Spain
Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, Madrid, Spain

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Luca Cristofolini Department of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum - Università di Bologna, Bologna, Italy

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Dennis Janssen Radboud University Medical Center, Radboud Research Institute, Orthopaedic Research Lab, Nijmegen, the Netherlands

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Bernd Grimm Luxembourg Institute of Health, Human Motion, Orthopaedics, Sports Medicine & Digital Methods Group, Transversal Activities, Luxembourg

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Alexander Giurea Department of Orthopaedic Surgery, Medical University of Vienna, Vienna, Austria

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Marcus Jäger Department of Orthopaedics, Trauma & Reconstructive Surgery St. Marien Hospital Mülheim an der Ruhr & Chair of Orthopaedics and Trauma Surgery University of Duisburg–Essen, Essen, Germany

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Francesco Siccardi Medacta International SA, Research & Development & Medical Affairs, Castel San Pietro, Switzerland

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Søren Overgaard Copenhagen University Hospital, Department of Orthopaedic Surgery and Traumatology, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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properties leads to uncertainty as to how to present (on the part of the applicant firm) and assess (on the part of the notified body and the clinical study surgeon) the methods and results of the pre-clinical and clinical evaluation ( 1 ). This ‘regulatory

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1530/EOR-23-0054
Volume/Issue:
Volume 8: Issue 7
Open access