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Alexios D. Iliadis Centre for Orthopaedics, The Royal London and Barts and The London Children’s Hospitals, Barts Health NHS Trust, London, UK

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Manoj Ramachandran Centre for Orthopaedics, The Royal London and Barts and The London Children’s Hospitals, Barts Health NHS Trust, London, UK

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adjacent joint space. The epiphyses of children aged less than 18 months are vascularised by transphyseal vessels. 7 This can facilitate haematogenous spread of bone infection from the metaphysis to the epiphysis and the adjoining joint space, and

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Martin McNally The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Irene Sigmund The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK
Department of Orthopaedics and Trauma Surgery, Medical University of Vienna, Austria

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Andrew Hotchen The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Ricardo Sousa Porto Bone and Joint Infection Group (GRIP), Department of Orthopaedics, Centro Hospitalar Universitario Santo António and CUF-Hospitais e Clinicas, Portugal

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Conference later that year but was not universally accepted and was not endorsed by MSIS or the European Bone Joint Infection Society (EBJIS). One major concern about the early definitions was that they presented a bimodal clinical decision (infected or not

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Joseph Genevière Faculty of Medicine, University of Geneva, Geneva, Switzerland
Co-first authors and equal contributors

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Shawna McCallin Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors

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Angela Huttner Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

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Truong-Thanh Pham Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Domizio Suva Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Introduction Bone and joint infections include any infection of the bone (osteomyelitis), joint (septic arthritis) or implants related to these structures (periprosthetic joint infections [PJI], fracture-related infections [FRI] involving

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Ricardo Sousa Department of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, Portugal
Porto Bone and Joint Infection Group (GRIP), Centro Hospitalar Universitário do Porto and Grupo TrofaSaude, Portugal

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André Carvalho Department of Orthopaedics, Centro Hospitalar Universitário do Porto, Porto, Portugal

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Ana Cláudia Santos Porto Bone and Joint Infection Group (GRIP), Centro Hospitalar Universitário do Porto and Grupo TrofaSaude, Portugal
Department of Microbiology, Centro Hospitalar Universitário do Porto, Porto, Portugal

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Miguel Araújo Abreu Porto Bone and Joint Infection Group (GRIP), Centro Hospitalar Universitário do Porto and Grupo TrofaSaude, Portugal
Department of Microbiology, Centro Hospitalar Universitário do Porto, Porto, Portugal

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available in most laboratories. For the time being, treating physicians must rely on adequate sampling to offer the best chance to identify the infecting pathogen(s). Ideally, decisions regarding complex bone and joint infections will be made in a

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Sylvain Steinmetz Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Diane Wernly Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Kevin Moerenhout Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Andrej Trampuz Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery (CMSC), Berlin, Germany

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Olivier Borens Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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prosthetic infections where joint aspiration can help preoperatively with diagnostics and establishment of a treatment plan. Compared to patients presenting for elective surgery, traumatic patients have generally more soft tissue damage, with even direct

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Christof Berberich Department of Medical Training and Education, Heraeus Medical GmbH, Wehrheim, Germany

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Pablo Sanz-Ruiz Department of Traumatology and Orthopaedic Surgery, General University Hospital Gregorio Marañón, Madrid, Spain

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systematic review . J Bone Joint Surg Br 2008 ; 90 : 915 – 919 . 4. Pulido L Ghanem E Joshi A Purtill JJ Parvizi J . Periprosthetic joint infection: the incidence, timing, and predisposing factors

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Elena Gálvez-Sirvent Department of Orthopaedic Surgery, “Infanta Elena” University Hospital, Valdemoro, Madrid, Spain
Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain

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Aitor Ibarzábal-Gil Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain

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E Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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.1016/j.ijsu.2017.03.085 ) 59. Gustilo RB Anderson JT . Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses . Journal of Bone and Joint Surgery: American

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Ismail Remzi Tözün Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Vahit Emre Ozden Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Goksel Dikmen Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Kayahan Karaytuğ Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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treatment of the soft tissue and bone infection. Antibiotic treatment should be continued until the second stage. Antibiotic-free waiting intervals and joint aspiration before the second stage are no longer recommended. According to ICM-2018, there is no

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Horacio Caviglia Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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Adrian Mejail Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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Maria Eulalia Landro Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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Nosratolah Vatani Department of Orthopaedic Surgery and Traumatology, Dr. Juan A. Fernández General Hospital, Argentina.

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anatomical reduction and internal fixation of fractures. 2 The objective of surgery is to achieve exact reduction to restore joint congruence, to adequately fix internal bone fragments, avoid displacement of the fracture and allow rapid rehabilitation

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Jurek Rafal Tomasz Pietrzak Arthroplasty Unit, Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), Johannesburg, South Africa

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Zia Maharaj Arthroplasty Unit, Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), Johannesburg, South Africa

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Lipalo Mokete Arthroplasty Unit, Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), Johannesburg, South Africa

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Nkhodiseni Sikhauli Arthroplasty Unit, Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), Johannesburg, South Africa

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Despite the development of several preventative measures, the annual incidence of peri-prosthetic joint infection (PJI) in THA is 1.17% and has a five-year mortality rate of 21.12%. 7 The annual cost for revisions due to PJI was US$566 million in 2009

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