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Hua Luo Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yongwei Su The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China

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Feng Xue Department of Orthopaedics, Fengxian District Central Hospital, Shanghai, People’s Republic of China

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Zhenghua Hong Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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, and infected sites. Figure 2 Forest plot of comparison: vancomycin vs control, outcome: surgical site infections. Table 3 Grading of Recommendations Assessment, Developing, and Evaluation used to assess the systematic review

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Duy Nguyen Anh Tran The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Bao Tu Thai Nguyen The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Tan Thanh Nguyen Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Yu-Pin Chen Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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Yi-Jie Kuo Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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impact on mental health ( 4 , 5 , 6 , 7 , 8 ). Smoking is associated with impaired wound healing and increased susceptibility to surgical site infections (SSIs) ( 9 , 10 , 11 ). SSIs, occurring in 1–20% of patients after ankle and calcaneal

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A Frodl Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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N Geisteuer Department of Orthopedics and Traumatology, Asklepios Hospital Harburg, Hamburg, Germany

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A Fuchs Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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T Nymark Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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H Schmal Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany
Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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combination of impaired blood supply and hyperglycemic states further increases the risk of surgical-site infections ( 3 , 4 ). In such cases, as reported by Willy et al. , closed-incisional negative pressure wound therapy (iNPWT) has shown clinical

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Chengxin Xie Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Liwei Zhang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Dehua Zhang Department of Emergency, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Lingjian Tao Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yong Zhao Department of Orthopedics, Shanghai Fengxian District Central Hospital, Shanghai 201400, China.

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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survival and efficacy of the knee replacement prosthesis, including poor alignment of the lower extremities, infection, aseptic loosening of the prosthesis, and anterior knee pain ( 1 ). Among these, surgical site infection (SSI) is the most common, with

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hui Yu Department of Hematology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China
Department of Hematology, Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, China

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Zhangfu Wang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Wenjun Pan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Lin Chen Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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contamination incision; and if the articles had missing data. Outcomes The primary outcome was the incidence of surgical site infection (SSI). Secondary outcomes included satisfaction and the incidence of other wound complications. Search strategy

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Low-dose dexamethasone during arthroplasty

What do we know about the risks?

Jessica T. Wegener Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Tim Kraal Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Markus F. Stevens Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Markus W. Hollmann Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Gino M.M.J. Kerkhoffs Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Daniël Haverkamp Department of Orthopedic Surgery, Slotervaart Ziekenhuis, Amsterdam, The Netherlands

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-operative strategies in preventing surgical site infections (SSI) after arthroplasty have been taken. Currently, conflicting views among orthopaedic surgeons and anaesthesiologists raise doubts on the use of dexamethasone during joint arthroplasty surgery. For

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain

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outpatient TKA than inpatient TKA, including component failure, surgical site infection, knee stiffness and deep vein thrombosis. 14 According to Gogineni et al, outpatient total hip arthroplasty (THA) and TKA in a well-selected patient is feasible in

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Philip F. Dobson Trauma and Orthopaedic Surgery, Royal Victoria Infirmary, Newcastle, UK

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Michael R. Reed Trauma and Orthopaedic Surgery, Royal Victoria Infirmary, Newcastle, UK

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further reduced infection. Despite the ongoing evolution and refinement of surgical practice, surgical site infection (SSI) remains a risk for every patient, including those undergoing primary total hip and knee arthroplasty procedures, and is associated

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Andreas Fontalis Royal National Orthopaedic Hospital NHS Trust, Brockley Hill, Stanmore, UK
Academic Unit of Bone Metabolism, University of Sheffield Medical School, Sheffield, UK

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Eustathios Kenanidis Academic Orthopaedic Unit, Aristotle University Medical School, Papageorgiou General Hospital, Thessaloniki, Greece
Centre of Orthopaedic and Regenerative Medicine (CORE), Center for Interdisciplinary Research and Innovation (CIRI), Aristotle University of Thessaloniki, Thessaloniki, Greece

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Katharine Bennett-Brown Chelsea and Westminster Hospital NHS Foundation Trust, Chelsea, London, UK

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Eleftherios Tsiridis Academic Orthopaedic Unit, Aristotle University Medical School, Papageorgiou General Hospital, Thessaloniki, Greece
Centre of Orthopaedic and Regenerative Medicine (CORE), Center for Interdisciplinary Research and Innovation (CIRI), Aristotle University of Thessaloniki, Thessaloniki, Greece

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outcomes included early (surgical site infection, pneumonia, urine infection, delirium, pulmonary embolism) and late complications (infection rate, loosening, dislocation and periprosthetic fractures), the implant of choice, surgical approach, length of

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Ting-Yu Tu Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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Chun-Yu Chen Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan
Department of Occupational Therapy, Shu-Zen Junior College of Medicine and Management, Kaohsiung City, Taiwan
Department of Biomedical Engineering, I-Shou University, Kaohsiung City, Taiwan

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Pei-Chin Lin Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
Department of Pharmacy, School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan

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Chih-Yang Hsu Department of Internal Medicine, Division of Nephrology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

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Kai-Cheng Lin Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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-analysis and systematic review was to analyze perioperative variables and clinical outcomes, such as surgery time, blood loss, length of hospital stays, Harris hip score (HHS), 36-Item Short Form Survey (SF-36), complication rate, surgical site infection rate

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