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Alli Gokeler University of Groningen, University Medical Center Groningen, Center for Human Movement Science, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands

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Bart Dingenen Rehabilitation Research Institute, Biomedical Research Institute, Faculty of Medicine and Life Sciences, UHasselt, Diepenbeek, Belgium

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Caroline Mouton Département de l’Appareil Locomoteur, Centre Hospitalier de Luxembourg – Clinique d’Eich, 76, rue d’Eich, L-1460 Luxembourg, Luxembourg

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Romain Seil Département de l’Appareil Locomoteur, Centre Hospitalier de Luxembourg – Clinique d’Eich, 76, rue d’Eich, L-1460 Luxembourg, Luxembourg and Sports Medicine Research Laboratory, Luxembourg Institute of Health, 76, rue d’Eich, L-1460 Luxembourg, Luxembourg

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. Post-operative care Using a criteria-based, evidence-based constructed approach to rehabilitation after ACL surgery is essential to systematically and successfully progress a patient through the rehabilitation process. 18 It is imperative to

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Nicola Ratto University of Torino, Italy

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Chiara Arrigoni University of Torino, Italy

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Federica Rosso AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Matteo Bruzzone AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Federico Dettoni AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Davide Edoardo Bonasia AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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Roberto Rossi AO Mauriziano Umberto I, Department of Orthopedics and Traumatology, Torino, Italy

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  • Total joint arthroplasty (TJA) is one of the most common orthopaedic procedures. Nevertheless, several complications can lead to implant failure.

  • Peri-prosthetic joint infections (PJI) certainly represent a significant challenge in TJA, constituting a major cause of prosthetic revision. The surgeon may have an important role in reducing the PJI rate by limiting the impact of significant risk factors associated to either the patient, the operative environment or the post-operative care.

  • In the pre-operative period, several preventive measures may be adopted to manage reversible medical comorbidities. Other recognised pre-operative risk factors are urinary tract infections, intra-articular corticosteroid injections and nasal colonisation with Staphylococcus (S.) aureus, particularly the methicillin-resistant strain (MRSA).

  • In the intra-operative setting, protective measures for PJI include antibiotic prophylaxis, surgical-site antisepsis and use of pre-admission chlorhexidine washing and pulsed lavage during surgery. In this setting, the use of plastic adhesive drapes and sterile stockinette, as well as using personal protection systems, do not clearly reduce the risk of infection. On the contrary, using sterile theatre light handles and splash basins as well as an increased traffic in the operating room are all associated with an increased risk for PJI.

  • In the post-operative period, other infections causing transient bacteraemia, blood transfusion and poor wound care are considered as risk factors for PJI.

Cite this article: Ratto N, Arrigoni C, Rosso F, Bruzzone M, Dettoni F, Bonasia DE, Rossi R. Total knee arthroplasty and infection: how surgeons can reduce the risks. EFORT Open Rev 2016;1: 339-344 DOI: 10.1302/2058-5241.1.000032.

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Nicolas de l’Escalopier Service de Chirurgie Orthopédique, Hôpital Raymond Poincaré, France
Service de Chirurgie Orthopédique, Traumatologie et Chirurgie Réparatrice des Membres, Hôpital d’Instruction des Armées Percy, France

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Marjorie Salga Service de médecine physique et réadaptation, Hôpital Raymond Poincaré, France

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Laure Gatin Service de Chirurgie Orthopédique, Hôpital Raymond Poincaré, France

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François Genêt Service de médecine physique et réadaptation, Hôpital Raymond Poincaré, France

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Philippe Denormandie Service de Chirurgie Orthopédique, Hôpital Raymond Poincaré, France

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interventions that will lead to positive functional outcomes involves five main points, which will be discussed further. These include: understanding the disease background, pre-operative patient management, the surgical strategy, post-operative care, and the

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Torben Bæk Hansen Aarhus University and The Lundback Centre for Hip and Knee Arthroplasty, Denmark

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-tissue trauma. 23 Simultaneous bilateral THA Simultaneous bilateral THAs have varying results in the literature when performed using conventional post-operative care routines. Otte et al 24 did a small study on 50 consecutive fast

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Nicolas Bonnevialle Orthopaedic Department and Biomechanics Department, IMFT CNRS URM 5502, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Florence Dauzères Orthopaedic Department, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Julien Toulemonde Orthopaedic Department, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Fanny Elia Orthopaedic Department, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Jean-Michel Laffosse Orthopaedic Department, CRIOAC and Biomechanics Department, IMFT CNRS, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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Pierre Mansat Orthopaedic Department and Biomechanics Department, IMFT CNRS URM 5502, Riquet Hospital, University Centre, Place Baylac, 31059 Toulouse, France

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high-power field in five high-power fields observed from histological analysis of peri-prosthetic tissue at ×400 magnification. Treatment Superficial wound infections are usually diagnosed in post-operative care and require local

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Lukas Fraissler University of Würzburg, Germany

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Christian Konrads University of Würzburg, Germany

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Maik Hoberg University of Würzburg, Germany

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Maximilian Rudert University of Würzburg, Germany

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Matthias Walcher University of Würzburg, Germany

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radiologically and a very low complication rate. 54 For further evaluation, more comparative long-term studies are needed. Post-operative care Our post-operative protocol consists of full weight-bearing mobilisation in a post-operative shoe for six

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Xavier Crevoisier University Hospital Center (CHUV) and University of Lausanne (UNIL), Switzerland

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Mathieu Assal Foot and Ankle Center, Clinique la Colline, Geneva, Switzerland

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Katarina Stanekova University Hospital Center (CHUV) and University of Lausanne (UNIL), Switzerland

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implanted through a lateral, trans-malleolar approach. Post-operative care usually includes the application of a below-knee walking cast for six weeks associated with immediate weight bearing as tolerated, followed by a physiotherapy programme to optimise

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Dieter Wirtz Department of Orthopaedic Surgery and Traumatology, University Hospital of Bonn, Germany

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Hendrik Kohlhof Department of Orthopaedic Surgery and Traumatology, University Hospital of Bonn, Germany

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and less morbidity. At our institution, we created an integrated geriatric-orthopaedic unit devoted to the post-operative care of elderly patients undergoing elective as well as non-elective orthopaedic procedures (Integrated Geriatric

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Allan Roy Sekeitto Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Nkhodiseni Sikhauli Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Dick Ronald van der Jagt Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Lipalo Mokete Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Jurek R.T. Pietrzak Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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functional outcomes at six weeks. 51 However, long-term outcome studies show equivocal results. 52 , 53 The review of the data favours a cemented femoral stem. 13 Post-operative care Aggressive pain management, multi-modal VTE

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Yusuf Omar Qalib Department of Orthopaedics, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China
These authors contributed equally to this work

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Yicun Tang Department of Orthopaedics, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China
These authors contributed equally to this work

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Dawei Wang Department of Orthopaedics, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China

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Baizhou Xing Department of Orthopaedics, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China

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Xingming Xu Department of Orthopaedics, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China

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Huading Lu Department of Orthopaedics, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China

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, as mentioned earlier, there still is no consensus as to post-operative care. For instance, many doctors allow full weight-bearing directly after surgery and so on. Conclusion Long negligence of MRL created scarcity of information regarding

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