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James Wee and Gowreeson Thevendran

Introduction Orthobiologics are biological substances that are used therapeutically for their positive effects on healing skeletal and soft-tissue injuries. The use of such biological agents in the field of orthopaedic surgery has been drawing

Hamid Rahmatullah Bin Abd Razak, Daniel Chew, Zepur Kazezian, and Anthony M.J. Bull

orthobiologic treatment options. There are many treatment modalities that now fit this overarching label. These include (in order of appearance over recent decades) whole blood therapy, traditional prolotherapy, platelet-rich plasma (PRP), bone marrow aspirate

Maria E Dey Hazra, Rony-Orijit Dey Hazra, Jared A Hanson, Phob Ganokroj, Matthew L Vopat, Joan C Rutledge, Kohei Yamaura, Sunikom Suppauksorn, and Peter J Millett

  • While functional reconstruction of massive irreparable rotator cuff tears remains a challenge, current techniques aimed at recentering and preventing superior migration of the humeral head allow for clinical and biomechanical improvements in shoulder pain and function.

  • Recentering of the glenohumeral joint reduces the moment arm and helps the deltoid to recruit more fibers, which compensates for insufficient rotator cuff function and reduces joint pressure.

  • In the past, the concept of a superior capsular reconstruction with a patch secured by suture anchors has been used.

  • However, several innovative arthroscopic treatment options have also been developed.

  • The purpose of this article is to present an overview of new strategies and surgical techniques and if existing present initial clinical results.

  • Techniques that will be covered include rerouting the long head of the biceps tendon, utilization of the biceps tendon as an autograft to reconstruct the superior capsule, utilization of a semitendinosus tendon allograft to reconstruct the superior capsule, superior capsular reconstruction with dermal allografts, and subacromial spacers.

Karthik Karuppaiah and Joydeep Sinha

. Restore orthobiologic implant: not recommended for augmentation of rotator cuff repairs . J Bone Joint Surg Am 2007 ; 89 : 786 – 791 . 19. American Academy of Orthopaedic Surgeons . Optimizing the management of rotator cuff problems

Hagen Schmal, Michael Brix, Mats Bue, Anna Ekman, Nando Ferreira, Hans Gottlieb, Søren Kold, Andrew Taylor, Peter Toft Tengberg, Ilija Ban, and Danish Orthopaedic Trauma Society

-shell biphasic bioactive ceramic microspheres . Sci Rep 2018 ; 8 : 3385 . 50. Calcei JG Rodeo SA . Orthobiologics for bone healing . Clin Sports Med 2019 ; 38 : 79 – 95 . 51. Murahashi Y Yano F

Paul L Rodham, Vasileios P Giannoudis, Nikolaos K Kanakaris, and Peter V Giannoudis

grafts, bone substitutes and orthobiologics: the bridge between basic science and clinical advancements in fracture healing . Organogenesis 2012 8 114 – 124 . ( https://doi.org/10.4161/org.23306 ) 12. Burchardt H . The biology of bone graft repair

George D Chloros, Christos D Kakos, Ioannis K Tastsidis, Vasileios P Giannoudis, Michalis Panteli, and Peter V Giannoudis

stainless steel screw Refracture, bent screw 6 months Three were revised to a bigger size screw, while orthobiologics and external bone stimulators were also used to augment healing. Fourth patient was revised to the same screw, but also required a

Victor Lu, Maria Tennyson, Andrew Zhou, Ravi Patel, Mary D Fortune, Azeem Thahir, and Matija Krkovic

://doi.org/10.3113/FAI.2010.0164 ) 10.3113/FAI.2010.0163 69. Roberts TT Rosenbaum AJ . Bone grafts, bone substitutes and orthobiologics: the bridge between basic science and clinical advancements in fracture healing . Organogenesis 2012 8 114– 124