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Young Yi Department of Orthopaedic Surgery, Inje University, Seoul Paik Hospital, 85, 2-ga, Jeo-dong, Jung-gu, Seoul, 100-032, Republic of Korea

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Woochun Lee Seoul Foot and Ankle Center, Dubalo Orthopaedic Clinic, 764-30, Bang bae dong, Seochogu, Seoul, 06554, Republic of Korea.

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deformity when there is a varus deformity of the tibial plafond and degenerative arthritis of knee and ankle ( Fig. 2 ). However, most authors have performed peri-talar osteotomies for joint preservation in asymmetrical ankle arthritis. Common joint

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Hamid Rahmatullah Bin Abd Razak Department of Bioengineering, Imperial College London, London, UK
Sengkang General Hospital, Singapore
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Daniel Chew Faculty of Medicine, Imperial College London, London, UK
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Zepur Kazezian Department of Bioengineering, Imperial College London, London, UK

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Anthony M.J. Bull Department of Bioengineering, Imperial College London, London, UK

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  • Osteoarthritis (OA) is a global health issue with myriad pathophysiological factors and is one of the most common causes of chronic disability in adults due to pain and altered joint function.

  • The end stage of OA develops from a destructive inflammatory cycle, driven by the pro-inflammatory cytokines interleukin-1β (IL-1β) and tumour necrosis factor alpha (TNFα).

  • Owing to the less predictable results of total knee arthroplasty (TKA) in younger patients presenting with knee OA, there has been a surge in research evaluating less invasive biological treatment options, one of which is autologous protein solution (APS).

  • APS is an autologous blood derivative obtained by using a proprietary device, made of APS separator, which isolates white blood cells (WBCs) and platelets in a small volume of plasma, and APS concentrator, which further concentrates platelets, WBCs and plasma proteins, resulting in a concentrated solution with high levels of growth factors including the anti-inflammatory mediators against IL-1β and TNFα.

  • A single intraarticular injection of APS appears to be a promising solution for treatment of early-stage OA from current evidence, the majority of which comes from preclinical studies.

  • More clinical studies are needed before APS can be widely accepted as a treatment modality for OA.

Cite this article: EFORT Open Rev 2021;6:716-726. DOI: 10.1302/2058-5241.6.200040

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Bülent Atilla Hacettepe University Department of Orthopaedics and Traumatology, Ankara, Turkey

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Sancar Bakırcıoğlu Hacettepe University Department of Orthopaedics and Traumatology, Ankara, Turkey

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Alexander J. Shope Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

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Javad Parvizi Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

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appropriate care and treatment. 11 Magnetic resonance imaging (MRI) is an indispensable tool for detection of the initial lesion of ONFH with 90–100% sensitivity. 12 , 13 Despite the lack of concrete data regarding the most optimal joint-preservation

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Abdelkader Shekhbihi Department of Trauma Surgery, Lörrach District Hospital, Baden-Württemberg, Lörrach, Germany

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Stefan Bauer Ensemble Hospitalier de la Côte, Morges, Switzerland.
School of Surgery, University of Western Australia, Perth, Australia

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Arnaud Walch Chirurgie Orthopédique et Traumatologique du Membre Superieur, Hopital Edouard Herriot, Lyon, France

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Winfried Reichert Department of Trauma Surgery, Lörrach District Hospital, Baden-Württemberg, Lörrach, Germany

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Gilles Walch Ramsay Générale de Santé, Hôpital privé Jean Mermoz, Centre Orthopédique Santy, Lyon, France

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Pascal Boileau Department of Orthopaedics and Sports Surgery, University Institute of Locomotion and Sports, Nice, France

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  • The Trillat procedure, initially described by Albert Trillat, is historically one of the first techniques for addressing recurrent anterior shoulder instability, incorporating fascinating biomechanical mechanisms.

  • After lowering, medializing, and fixing the coracoid process to the glenoid neck, the subcoracoid space is reduced, the subscapularis lowered, and its line of pull changed, accentuating the function of the subscapularis as a humeral head depressor centering the glenohumeral joint. Furthermore, the conjoint tendon creates a ‘seatbelt’ effect, preventing anteroinferior humeral head dislocation.

  • Even though contemporary preferences lean towards arthroscopic Bankart repair with optional remplissage, bone augmentation, and the Latarjet procedure, enduring surgical indications remain valid for the Trillat procedure, which offers joint preservation and superior outcomes in two distinct scenarios: (i) older patients with massive irreparable cuff tears and anterior recurrent instability with an intact subscapularis tendon regardless of the extent of glenoid bone loss; (ii) younger patients with instability associated shoulder joint capsule hyperlaxity without concomitant injuries (glenoid bone loss, large Hill–Sachs lesion).

  • Complications associated with the Trillat procedure include recurrent anterior instability, potential overtightening of the coracoid, leading to pain and a significant reduction in range of motion, risk of subcoracoid impingement, and restriction of external rotation by up to 10°, a limitation that is generally well-tolerated.

  • The Trillat procedure may be an effective alternative technique for specific indications and should remain part of the surgical armamentarium for addressing anterior shoulder instability.

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Stig Storgaard Jakobsen Department of Orthopaedic Surgery, Aarhus University Hospital, Denmark

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Søren Overgaard Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Denmark

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Kjeld Søballe Department of Orthopaedic Surgery, Aarhus University Hospital, Denmark

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Ole Ovesen Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Denmark

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Bjarne Mygind-Klavsen Department of Orthopaedic Surgery, Aarhus University Hospital, Denmark

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Christian Andreas Dippmann Section for Sports Traumatology M51, Department of Orthopaedic Surgery, Bispebjerg Hospital, Denmark

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Michael Ulrich Jensen Department of Orthopaedics, Aalborg University Hospital, Denmark

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Jens Stürup Department of Orthopaedics, National University Hospital, Denmark

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Jens Retpen Department of Orthopaedic Surgery, Copenhagen University Hospital, Gentofte, Denmark

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Preservation Surgery ; vol 1 . New York, NY : Springer-Verlag New York Inc. , 2015 . 18. Nho SJ Leunig M Larson CM Bedi A Kelly BT , eds. Hip Arthroscopy and Hip Joint Preservation Surgery ; vol 2 . New

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Carlos Maynou CHU Lille, Orthopaedic Department, F-59000 Lille, France

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Christophe Szymanski CHU Lille, Orthopaedic Department, F-59000 Lille, France

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Alexis Thiounn CHU Lille, Orthopaedic Department, F-59000 Lille, France

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the foot becomes stiffer and less adaptable. Joint preservation and decreased deterioration of the deformities can be obtained by balancing of the affected muscles; therefore, various soft-tissue procedures are prefered while the deformity is flexible

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Giuseppe Toro Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘Luigi Vanvitelli’, Naples, Italy.
Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.

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Antimo Moretti Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘Luigi Vanvitelli’, Naples, Italy.

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Marco Paoletta Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘Luigi Vanvitelli’, Naples, Italy.

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Annalisa De Cicco Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘Luigi Vanvitelli’, Naples, Italy.

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Adriano Braile Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘Luigi Vanvitelli’, Naples, Italy.

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Alfredo Schiavone Panni Department of Medical and Surgical Specialties and Dentistry, University of Campania ‘Luigi Vanvitelli’, Naples, Italy.

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According to Ayoub and Gad, 5 age (younger than 30 years) and post-operative neck-shaft angle (lower than 130°) are the main predicting factors for the best outcomes of surgical joint preservation techniques. On the contrary, time elapsed since the

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Markus S. Hanke Department of Orthopaedic and Trauma Surgery, Inselspital, University of Bern, Bern, Switzerland

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Till D. Lerch Department of Diagnostic, Interventional and Pediatric Radiology University Hospital of Bern, Inselspital, University of Bern, Bern, Switzerland

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Florian Schmaranzer Department of Diagnostic, Interventional and Pediatric Radiology University Hospital of Bern, Inselspital, University of Bern, Bern, Switzerland

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Malin K. Meier Department of Orthopaedic and Trauma Surgery, Inselspital, University of Bern, Bern, Switzerland

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Simon D. Steppacher Department of Orthopaedic and Trauma Surgery, Inselspital, University of Bern, Bern, Switzerland

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Klaus A. Siebenrock Department of Orthopaedic and Trauma Surgery, Inselspital, University of Bern, Bern, Switzerland

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Perthes disease, torsional abnormalities together with the development of new surgical approaches and procedures, have revolutionized the field of joint preserving surgery. The utilization of joint preservation operations including hip arthroscopy

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Ahmed Mabrouk Mid Yorkshire Teaching Hospitals, Yorkshire, United Kingdom
Institut du mouvement et de l’appareil locomoteur, Marseille, France

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Jae-Sung An Institut du mouvement et de l’appareil locomoteur, Marseille, France

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Kristian Kley Orthoprofis Hannover, Hannover, Germany

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Komal Tapasvi The Orthopaedic Speciality Clinic, Pune, India

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Sachin Tapasvi The Orthopaedic Speciality Clinic, Pune, India

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Matthieu Ollivier Institut du mouvement et de l’appareil locomoteur, Marseille, France

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compartment cartilage status was recorded at the first and second stages of arthroscopy, before and after MOWHTO, according to the International Cartilage Regeneration and Joint Preservation Society grade (ICRS) ( 25 ). ICRS grade 1 involved superficial

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Joaquim Soares do Brito Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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André Spranger Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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Paulo Almeida Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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José Portela Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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Irene Barrientos-Ruiz Orthopedics Department, University Hospital of La Paz, Madrid

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treatment of giant-cell tumor around the knee: a retrospective study of 27 cases . Medicine (Baltimore) 2018 ; 97 : e13154 . 22. Ayerza MA Aponte-Tinao LA Farfalli GL Restrepo CA Muscolo DL . Joint

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