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Folkhälsan Research Center, Helsinki, Finland
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Department of Reconstructive Orthopaedics, Karolinska University Hospital, Stockholm, Sweden
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contribute to the phenotype of scoliosis are unclear. Furthermore, the currently well-known and replicated loci can only explain a small percentage of all possible loci and the missing heritability remains a concern ( 14 , 15 , 16 , 17 , 18 , 19 , 20
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Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia
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School of Medicine, Faculty of Medicine and Health Sciences, Taylor's University, Selangor, Malaysia
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Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia
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cytogenetic aberrations on chromosomes 5 and 11 for DC ( 24 ). Familial and twin studies Twin studies make a useful tool in identifying genetic influences in the heritability of a disease. In a comparative study of two pairs of twins, it was observed
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According to a single-centre study hip dysplasia is associated with osteogenesis imperfecta (OI), a heritable skeletal disorder that is usually due to mutation in one of the two genes, COL1A1 and COL1A2, that code for collagen type I a-chains. This study
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. The heritability of Dupuytren’s disease: familial aggregation and its clinical significance . J Hand Surg Am 2006 ; 31 : 204 - 210 . 15. Larsen S Krogsgaard DG Larsen LA . Genetic and environmental influences in
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands
Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands
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Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands
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outcome ( 46 ). As a trait, resilience refers to a characteristic of personality, which is heritable and relatively stable across time ( 47 ). The American Psychological Association defines resilience as ‘the process and outcome of successfully adapting to
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true incidence of tarsal coalition is unknown, estimates vary from 1% to 13%, 1 , 2 thereby making it one of the commonest foot and ankle pathologies in children. Coalitions are bilateral in approximately 50% of cases, and there is a heritable
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, National Library of Medicine , 2000 .( https://doi.org/10.1002/(SICI)1098-1004(200001)15:1<57::AID-HUMU12>3.0.CO;2-G ) 30 White CB The mucopolysaccharidoses . In McKusick’s Heritable Disorders of Connective Tissue , pp. 367 – 350 . Ed Beighton P
