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Shankar Aissvarya Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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King-Hwa Ling Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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Manohar Arumugam Department of Orthopaedics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
School of Medicine, Faculty of Medicine and Health Sciences, Taylor's University, Selangor, Malaysia

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Karuppiah Thilakavathy Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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genetic variants located in exonic regions that have been identified in DC and explore their connections with these molecular pathways. Genetics aspects of DC Genetic variants associated with DC DC is a multifactorial disease influenced by both

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Tian Cheng Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden

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Elisabet Einarsdottir Department of Gene Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, Royal Institute of Technology, Stockholm, Sweden

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Juha Kere Department of Biosciences and Nutrition (BioNut), Karolinska Institutet, Stockholm, Sweden
Folkhälsan Research Center, Helsinki, Finland

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Paul Gerdhem Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden
Department of Reconstructive Orthopaedics, Karolinska University Hospital, Stockholm, Sweden

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). Heritability is an important parameter in quantitative genetics and estimates the proportion of a specific phenotypic variance that is attributed to differences in genes in a specific population ( 21 ). Heritability, however, is not a direct measure of the

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Rita Grazina Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Sérgio Teixeira Serviço de Cirurgia Plástica, Reconstrutiva e Estética e Unidade de Queimados, Centro Hospitalar de São João, Portugal

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Renato Ramos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Henrique Sousa Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Andreia Ferreira Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Rui Lemos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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overview . Plast Reconstr Surg 2000 ; 106 : 125 - 134 . 13. Burge P . Genetics of Dupuytren’s disease . Hand Clin 1999 ; 15 : 63 - 71 . 14. Hindocha S John S Stanley JK Watson SJ Bayat A

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Bowen Lai Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China

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Heng Jiang Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China

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Yuan Gao Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China

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Xuhui Zhou Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China

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RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 163 ENDOCRINOLOGY & METABOLISM 137 CELL BIOLOGY 93 PEDIATRICS 92 PATHOLOGY 87 RESEARCH & EXPERIMENTAL MEDICINE 87 GENETICS & HEREDITY 84 GENERAL & INTERNAL

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Amer Sebaaly Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon
Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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Mohammad Daher Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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Bendy Salameh Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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Ali Ghoul Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon

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Samuel George Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon

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Sami Roukoz Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon
Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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anomalies: aetiology and relationship to spina bifida cystica . Journal of Medical Genetics 1975 12 280 – 288 . ( https://doi.org/10.1136/jmg.12.3.280 ) 1100836 3. Giampietro PF Pourquie O Raggio C Ikegawa S Turnpenny PD Gray R Dunwoodie SL

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Manuel Monteagudo Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Pilar Martínez de Albornoz Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Borja Gutierrez Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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José Tabuenca Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Ignacio Álvarez Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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, gender, body weight, heel spurs, nerve entrapment, systemic disease, biomechanical dysfunction, and genetics. Extrinsic factors included footwear, sport, lifestyle, foot/ankle/leg deformities, and occupation. Age : There is a body of literature on the

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Pierre Hoffmeyer Editor in Chief, EFORT Open Reviews

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desperation there blossomed a light, a hope, an expectation. Vaccines were arriving on the scene. In such a short time, it is a prodigious feat involving molecular genetics, pharma and medicine. The end of the tunnel was nigh with a promise that life would

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İlker Eren Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Cemil Cihad Gedik Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Uğur Kılıç Koç University, School of Medicine, Istanbul, Turkey

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Berk Abay Koç University, School of Medicine, Istanbul, Turkey

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Olgar Birsel Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Mehmet Demirhan Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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molecular study in a north-east Italian population sample . Clinical Genetics 2009 75 550 – 555 . ( https://doi.org/10.1111/j.1399-0004.2009.01158.x ) 10.1111/j.1399-0004.2009.01158.x 10. Zatz M Marie SK Cerqueira A Vainzof M Pavanello RC Passos

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Marco Gupton MountainView Regional Medical Center, Orthopaedic Surgery Residency, Las Cruces, New Mexico, USA

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Jessica Burns Department of Orthopaedic Surgery, Phoenix Children’s Hospital, Phoenix, Arizona, USA

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antimicrobial sensitivities using culture and molecular genetics ( 3 , 4 , 5 , 7 ). Culture-based modalities have been the gold standard for the diagnosis and treatment of musculoskeletal infection ( 8 , 9 ); however, cultures have significant limitations

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Ioannis Gkiatas Orthopaedic Department, School of Medicine, University of Ioannina, Ioannina, Greece

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Anastasia Boptsi Orthopaedic Department, School of Medicine, University of Ioannina, Ioannina, Greece

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Dimitra Tserga Orthopaedic Department, School of Medicine, University of Ioannina, Ioannina, Greece

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Ioannis Gelalis Orthopaedic Department, School of Medicine, University of Ioannina, Ioannina, Greece

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Dimitrios Kosmas Orthopaedic Department, School of Medicine, University of Ioannina, Ioannina, Greece

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Emilios Pakos Orthopaedic Department, School of Medicine, University of Ioannina, Ioannina, Greece

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-control, cohort, familial studies and reviews on DDH-linked genetic analysis indexed in the PubMed database. Our search was in MeSH terms using: “developmental dysplasia of the hip”/congenital, genetics, genes. Types of studies Case-control studies have

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