King’s Global Health Partnerships, School of Life Course and Population Sciences, King’s College London, London, UK
Search for other papers by Elizabeth K Tissingh in
Google Scholar
PubMed
Search for other papers by Leonard Marais in
Google Scholar
PubMed
Search for other papers by Antonio Loro in
Google Scholar
PubMed
Search for other papers by Deepa Bose in
Google Scholar
PubMed
Search for other papers by Nilo T Paner in
Google Scholar
PubMed
Department of Orthopaedics, University of the Philippines, Philippine General Hospital Manila, The Phillipines
Search for other papers by Jamie Ferguson in
Google Scholar
PubMed
Search for other papers by Mario Morgensten in
Google Scholar
PubMed
Search for other papers by Martin McNally in
Google Scholar
PubMed
Introduction and aims The global burden of fracture-related infection (FRI) is likely to be concentrated in countries with limited healthcare resources. Conditions associated with FRI (road injuries, other musculoskeletal disorders, falls and
Search for other papers by Martin McNally in
Google Scholar
PubMed
Search for other papers by Geertje Govaert in
Google Scholar
PubMed
Search for other papers by Maria Dudareva in
Google Scholar
PubMed
Search for other papers by Mario Morgenstern in
Google Scholar
PubMed
Search for other papers by Willem-Jan Metsemakers in
Google Scholar
PubMed
be confusing and do not give specific indication of the relationship with a fracture. The FRI Consensus Group published the initial definition criteria in 2018 8 and the term ‘fracture-related infection’ was adopted to encompass all infections
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)
Search for other papers by Tristan Ferry in
Google Scholar
PubMed
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium
Search for other papers by Jolien Onsea in
Google Scholar
PubMed
Search for other papers by Tiphaine Roussel-Gaillard in
Google Scholar
PubMed
Search for other papers by Cécile Batailler in
Google Scholar
PubMed
Search for other papers by Thomas Fintan Moriarty in
Google Scholar
PubMed
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium
Search for other papers by Willem-Jan Metsemakers in
Google Scholar
PubMed
Introduction Musculoskeletal infections (MSIs), including periprosthetic joint infection (PJI) and fracture-related infection (FRI), remain a devastating complication in modern trauma and orthopaedic surgery, with significant financial and
Search for other papers by Sylvain Steinmetz in
Google Scholar
PubMed
Search for other papers by Diane Wernly in
Google Scholar
PubMed
Search for other papers by Kevin Moerenhout in
Google Scholar
PubMed
Search for other papers by Andrej Trampuz in
Google Scholar
PubMed
Search for other papers by Olivier Borens in
Google Scholar
PubMed
infections (FRI) ( Table 1 ). 7 Table 1. Definition of infection after fracture-related infection, as proposed by Metsemakers et al. 7 Confirmatory criteria Fistula, sinus or wound breakdown (probe to bone or implant
Porto Bone and Joint Infection Group (GRIP), Centro Hospitalar Universitário do Porto and Grupo TrofaSaude, Portugal
Search for other papers by Ricardo Sousa in
Google Scholar
PubMed
Search for other papers by André Carvalho in
Google Scholar
PubMed
Department of Microbiology, Centro Hospitalar Universitário do Porto, Porto, Portugal
Search for other papers by Ana Cláudia Santos in
Google Scholar
PubMed
Department of Microbiology, Centro Hospitalar Universitário do Porto, Porto, Portugal
Search for other papers by Miguel Araújo Abreu in
Google Scholar
PubMed
best practices for obtaining adequate samples in the most frequent clinical scenarios: (a) native and prosthetic joint infections; (b) osteomyelitis and fracture-related infections; (c) spinal infections and; (d) diabetic foot infections. Although a
Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain
Search for other papers by Elena Gálvez-Sirvent in
Google Scholar
PubMed
Search for other papers by Aitor Ibarzábal-Gil in
Google Scholar
PubMed
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain
Search for other papers by E Carlos Rodríguez-Merchán in
Google Scholar
PubMed
patients with fracture-related infection: a systematic review and critical appraisal . BioMed Research International 2021 2021 7742227. ( https://doi.org/10.1155/2021/7742227 ) 68. Jensen NM Steenstrup S Ravn C Schmal H Viberg B . The use of
Co-first authors and equal contributors
Search for other papers by Joseph Genevière in
Google Scholar
PubMed
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors
Search for other papers by Shawna McCallin in
Google Scholar
PubMed
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Search for other papers by Angela Huttner in
Google Scholar
PubMed
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
Search for other papers by Truong-Thanh Pham in
Google Scholar
PubMed
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
Search for other papers by Domizio Suva in
Google Scholar
PubMed
Introduction Bone and joint infections include any infection of the bone (osteomyelitis), joint (septic arthritis) or implants related to these structures (periprosthetic joint infections [PJI], fracture-related infections [FRI] involving
Search for other papers by Paul L Rodham in
Google Scholar
PubMed
Search for other papers by Vasileios P Giannoudis in
Google Scholar
PubMed
Department of Trauma & Orthopaedics, University of Leeds, Leeds, United Kingdom of Great Britain and Northern Ireland
Search for other papers by Nikolaos K Kanakaris in
Google Scholar
PubMed
Search for other papers by Peter V Giannoudis in
Google Scholar
PubMed
rapid resorption over a period of 4–12 weeks and can be combined with antibiotics increasing interest in these molecules where fracture-related infection is present ( 11 ). The most commonly encountered commercially available products include osteoset
Search for other papers by Elena Gálvez-Sirvent in
Google Scholar
PubMed
Search for other papers by Aitor Ibarzábal-Gil in
Google Scholar
PubMed
Search for other papers by E. Carlos Rodríguez-Merchán in
Google Scholar
PubMed
IJpma FFA et al. High diagnostic accuracy of white blood cell scintigraphy for fracture related infections: results of a large retrospective single-center study . Injury 2018 ; 49 : 1085 – 1090 . 10. Liodakis E Liodaki
Search for other papers by Karl Stoffel in
Google Scholar
PubMed
Search for other papers by Christoph Sommer in
Google Scholar
PubMed
Search for other papers by Mark Lee in
Google Scholar
PubMed
Search for other papers by Tracy Y Zhu in
Google Scholar
PubMed
Search for other papers by Karsten Schwieger in
Google Scholar
PubMed
Search for other papers by Christopher Finkemeier in
Google Scholar
PubMed
achieved full weight-bearing at a mean ( s.d. ) of 16 (5) weeks. NR No patients with peri- and interprosthetic fractures had complication; 1 out of 5 (20%) patients with reoperations developed a fracture-related infection. *Functional