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Geovanny Ruiz Ponce Health Sciences University, School of Medicine, Ponce, Puerto Rico

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Norberto J Torres-Lugo Department of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico

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Pablo Marrero-Ortiz Department of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico

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Humberto Guzmán Department of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico

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Gerardo Olivella Department of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico

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Norman Ramírez Department of Orthopaedic Surgery, Mayagüez Medical Center, Mayagüez, Puerto Rico

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Introduction Early-onset Scoliosis (EOS) is a term experts adopted to refer to pathologies of the growing spine that manifest and progress in different forms. Historically, its challenging nature has made it difficult to introduce a

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Ilkka J. Helenius Department of Pediatric Orthopedic Surgery, University of Turku and Turku University Hospital, Turku, Finland

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Introduction Early-onset scoliosis (EOS) is defined as a spinal deformity occurring before ten years of age. 1 , 2 Untreated EOS or early spinal fusion resulting in a short spine is associated with increased mortality and cardiopulmonary

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Alpaslan Senkoylu Gazi University, Department of Orthopaedics and Traumatology, Ankara, Turkey

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Rolf B. Riise Oslo University Hospital, Orthopaedic Clinic, Oslo, Norway

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Emre Acaroglu Ankara Spine Centre, Ankara, Turkey

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Ilkka Helenius University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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development, a new description was developed. Early onset scoliosis (EOS) now refers to a coronal plain curvature of more than 10 degrees with onset earlier than 10 years of age including all types of aetiologies such as idiopathic, congenital, neuromuscular

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Amer Sebaaly Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon
Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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Mohammad Daher Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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Bendy Salameh Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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Ali Ghoul Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon

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Samuel George Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon

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Sami Roukoz Department of Orthopedic Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon
Faculty of Medicine, Saint Joseph University, Beirut, Lebanon

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Bone and Joint Surgery: American Volume 2003 85 399 – 408 . ( https://doi.org/10.2106/00004623-200303000-00001 ) 63. Motoyama EK Yang CI Deeney VF . Thoracic malformation with early-onset scoliosis: effect of serial VEPTR expansion

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İlker Eren Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Cemil Cihad Gedik Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Uğur Kılıç Koç University, School of Medicine, Istanbul, Turkey

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Berk Abay Koç University, School of Medicine, Istanbul, Turkey

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Olgar Birsel Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Mehmet Demirhan Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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the quality of life (QoL), by intensely interfering with the activities of daily living ( 2 , 3 ). The patients typically become symptomatic in their late adolescent period. Early-onset FSHD has also been defined, where initial symptoms are documented

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Donald J. Davidson Research Department of Orthopaedics and Musculoskeletal Sciences, University College London, London, UK
Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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David Spratt Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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Alexander D. Liddle Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK
MSK Lab, Imperial College London, London, UK

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(< 3 months), delayed (between three and 12–24 months) and late (later than 12–24 months). 19 Early onset and delayed onset infection are thought to occur due to direct contamination at the time of surgery, with early onset being caused by more

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Jie Xiang Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Weibo Zhao Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xiao Luo Department of Radiology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Zhenghua Hong Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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age of 35 years. Unlike previously reported cases, our case involved a postmenopausal woman with an earlier onset time and a more extensive range of SSDH. The early increase in BNP was not obvious, and the primary manifestation was a sharp increase in

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Mukai Chimutengwende-Gordon Joint Reconstruction Unit, Royal National Orthopaedic Hospital Trust, Stanmore, UK

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James Donaldson Joint Reconstruction Unit, Royal National Orthopaedic Hospital Trust, Stanmore, UK

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George Bentley Joint Reconstruction Unit, Royal National Orthopaedic Hospital Trust, Stanmore, UK

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stresses in the adjacent intact cartilage. 7 – 9 If left untreated, progressive cartilage degeneration and ultimately ‘early-onset’ osteoarthritis may occur. 10 The management of chondral defects is challenging. Numerous surgical techniques have

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Rita Grazina Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Sérgio Teixeira Serviço de Cirurgia Plástica, Reconstrutiva e Estética e Unidade de Queimados, Centro Hospitalar de São João, Portugal

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Renato Ramos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Henrique Sousa Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Andreia Ferreira Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Rui Lemos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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, according to the works of Hindocha et al, 14 positive family history correlates with greater severity and earlier onset. Genetic influence has also been proven by the study of Larsen et al, that found a concordance rate of 0.37 between monozygotic twins

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Sakae Tanaka Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

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decrease in bone resorption. Patients with RANKL or RANK gene mutations develop a distinct subgroup of recessive osteopetrosis disease with very few osteoclasts in the skeletal tissues. 14 In contrast, familial expansile osteolysis, early-onset Paget

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