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Fan Wu
Fan Wu
Experimental Surgery and Regenerative Medicine, Department of Surgery, Ludwig-Maximilians-University (LMU), Munich, Germany
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Michael Nerlich
Michael Nerlich
Department of Trauma Surgery, University Regensburg Medical Center, Regensburg, Germany
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Denitsa Docheva
Denitsa Docheva
Experimental Trauma Surgery, Department of Trauma Surgery, University Regensburg Medical Center, Regensburg, Germany and Department of Medical Biology, Medical University-Plovdiv, Plovdiv, Bulgaria
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is a slow, continuous process consisting of degradation and deposition of ECM proteins. These primarily include proteoglycans and collagens. Various MMPs, ADAMs and ADAMTSs participate in the tendon repair process. For example, collagenases, such as
Low-dose dexamethasone during arthroplasty
What do we know about the risks?
Jessica T. Wegener
Jessica T. Wegener
Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands
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Tim Kraal
Tim Kraal
Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands
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Markus F. Stevens
Markus F. Stevens
Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands
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Markus W. Hollmann
Markus W. Hollmann
Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands
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Gino M.M.J. Kerkhoffs
Gino M.M.J. Kerkhoffs
Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands
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Daniël Haverkamp
Daniël Haverkamp
Department of Orthopedic Surgery, Slotervaart Ziekenhuis, Amsterdam, The Netherlands
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on the synthesis of collagen type I and III, collagenase, and tissue inhibitors of metalloproteinases . Br J Dermatol 2002 ; 147 : 859 - 68 . 35 Ehrlich HP , Tarver H , Hunt TK . Effects of vitamin A and
Hamid Rahmatullah Bin Abd Razak
Hamid Rahmatullah Bin Abd Razak
Department of Bioengineering, Imperial College London, London, UK
Sengkang General Hospital, Singapore
Joint first authors
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Sengkang General Hospital, Singapore
Joint first authors
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Daniel Chew
Daniel Chew
Faculty of Medicine, Imperial College London, London, UK
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Joint first authors
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Zepur Kazezian
Zepur Kazezian
Department of Bioengineering, Imperial College London, London, UK
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Anthony M.J. Bull
Anthony M.J. Bull
Department of Bioengineering, Imperial College London, London, UK
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; 278 : 45539 – 45545 . 51. Dejica VM Mort JS Laverty S et al. Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage . Arthritis
Mara Meyer Günderoth
Mara Meyer Günderoth
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery, Berlin, Germany
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
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Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
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Alexandra Bannach-Brown
Alexandra Bannach-Brown
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, QUEST Center for Responsible Research, Berlin, Germany
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Tobias Winkler
Tobias Winkler
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery, Berlin, Germany
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany
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Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany
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Johannes Keller
Johannes Keller
Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Robert Karl Zahn
Robert Karl Zahn
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery, Berlin, Germany
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Tazio Maleitzke
Tazio Maleitzke
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery, Berlin, Germany
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
Trauma Orthopaedic Research Copenhagen Hvidovre (TORCH), Department of Orthopaedic Surgery, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
Trauma Orthopaedic Research Copenhagen Hvidovre (TORCH), Department of Orthopaedic Surgery, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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sCT 1 Daily for 12 weeks Nasal spray † 100 IU or 400 IU Placebo Gou et al. ( 24 ) Rat M 40 OA Collagenase (type II) injections in the right L3–L6 facet joints sCT 1 Every 2 days for 8 weeks s.c. 16 IU/kg b.w./2
