Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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bone metastases are in the breast, prostate, lung, kidney, and thyroid. The evolution of a bone metastasis depends on the affected bone type and its location. The most common sites of bone metastases are the spine, proximal femur, pelvis, ribs, and
Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania
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Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania
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Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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intervention. These interventions aim to alleviate symptoms, especially since RCC bone metastases tend to be osteolytic ( 11 ). Even with advancements like T cell checkpoint and tyrosine kinase inhibitors, managing bone metastasis remains challenging ( 12 , 13
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However, there is no consensus in the guidelines or literature as to which types of long bone metastasis benefit from preoperative embolization in order to reduce blood loss. The primary aim of this systematic review was to identify long bone metastases
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parameters to consider when approaching a patient with bone metastasis, such as age, performance status, number and site of metastases, the free interval of disease, histotypes of the primary tumor, and expected survival ( 2 , 3 ). The treatment of long bone
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for an impending fracture, and an intramedullary nail with cement in the lesion or a DF-MTP should be considered. Fig. 6 Patient with solitary bone metastasis from non small cell lung carcinoma (diagnosed and treated 4.5 years ago). Metastasis of
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. 28 Risk factors for developing a bone metastasis were tumour size (> 5 cm), higher tumour grade, sub-type of the tumour (lobular carcinoma) and number of positive lymph nodes. For those patients with metastases in the bone, factors influencing
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. BMJ Case Rep 2017 . 23. Ota S Inoue R Shiozaki T . Atypical femoral fracture after receiving antiresorptive drugs in breast cancer patients with bone metastasis . Breast Cancer 2017 ; 24 : 601 – 607 . 24
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of cancer, infection, cardiovascular disease, delayed fracture healing, hypocalcaemia, or osteonecrosis of the jaw. In addition to its anti-osteoporotic function, denosumab prevents skeletal-related events in patients with bone metastasis from solid
