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Catalin Cirstoiu Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Bogdan Cretu Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Sergiu Iordache Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Mihnea Popa Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Bogdan Serban Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Adrian Cursaru Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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bone metastases are in the breast, prostate, lung, kidney, and thyroid. The evolution of a bone metastasis depends on the affected bone type and its location. The most common sites of bone metastases are the spine, proximal femur, pelvis, ribs, and

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Stijn E. W. Geraets Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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P. Koen Bos Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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Johan van der Stok Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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However, there is no consensus in the guidelines or literature as to which types of long bone metastasis benefit from preoperative embolization in order to reduce blood loss. The primary aim of this systematic review was to identify long bone metastases

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Elisa Pala Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Alberto Procura Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Giulia Trovarelli Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Antonio Berizzi Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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parameters to consider when approaching a patient with bone metastasis, such as age, performance status, number and site of metastases, the free interval of disease, histotypes of the primary tumor, and expected survival ( 2 , 3 ). The treatment of long bone

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Julie J. Willeumier Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Yvette M. van der Linden Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Michiel A.J. van de Sande Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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P.D. Sander Dijkstra Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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for an impending fracture, and an intramedullary nail with cement in the lesion or a DF-MTP should be considered. Fig. 6 Patient with solitary bone metastasis from non small cell lung carcinoma (diagnosed and treated 4.5 years ago). Metastasis of

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Miklós Szendrői Department of Orthopaedics, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary

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Imre Antal Department of Orthopaedics, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary

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Attila Szendrői Department of Urology, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary

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Áron Lazáry National Center for Spinal Disorders, H-1126 Budapest, Királyhágó u.1., Hungary

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Péter Pál Varga National Center for Spinal Disorders, H-1126 Budapest, Királyhágó u.1., Hungary

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. 28 Risk factors for developing a bone metastasis were tumour size (> 5 cm), higher tumour grade, sub-type of the tumour (lobular carcinoma) and number of positive lymph nodes. For those patients with metastases in the bone, factors influencing

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Morten Schultz Larsen Department of Orthopaedics and Traumatology, Odense University Hospital, Denmark

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Hagen Schmal Department of Orthopaedics and Traumatology, Odense University Hospital, Denmark

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. BMJ Case Rep 2017 . 23. Ota S Inoue R Shiozaki T . Atypical femoral fracture after receiving antiresorptive drugs in breast cancer patients with bone metastasis . Breast Cancer 2017 ; 24 : 601 – 607 . 24

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Sakae Tanaka Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

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of cancer, infection, cardiovascular disease, delayed fracture healing, hypocalcaemia, or osteonecrosis of the jaw. In addition to its anti-osteoporotic function, denosumab prevents skeletal-related events in patients with bone metastasis from solid

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