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), minced cartilage procedures for allografts and autografts replacement ( 10 , 11 ), and multiple generations of autologous chondrocyte implantation (ACI). The latter has evolved from the injection of cultured autologous chondrocytes below a periosteum
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to autologous chondrocyte implantation (ACI) except for very small lesions of less than 2 cm 2 . 25 Osteochondral allograft transplantation Fresh osteochondral allograft (OCA) transplantation is an alternative to OATS and may be useful in
Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Justus Maximilian University Wuerzburg, König-Ludwig-Haus, Brettreichstraße, Würzburg, Germany
Paracelsus Medizinische Privatuniversität, Strubergasse, Salzburg, Austria
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany
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Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany
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Martin-Luther-University Halle-Wittenberg, Universitätsklinikum Halle (Saale), DOUW - Abteilung für Unfall- und Wiederherstellungschirurgie, Ernst-Grube-Straße, Halle, Germany
BG-Klinikum Bergmannstrost Halle, Halle, Saale, Germany
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. AOFAS American Orthopedic Foot and Ankle Society ACI Autologous chondrocyte implantation (scientifically neutral term, includes protected trademarks like MACI®) DGOU German Society of Orthopedic and Trauma Surgeons BMS Bone
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Department of Orthopedic Surgery, National Taiwan University Hospital, Taiwan, Republic of China
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. The sealing of the defect with a collagen matrix after BMS describes the technique of autologous matrix-induced chondrogenesis (AMIC) ( 6 ). Autologous chondrocyte implantation (ACI) ( 7 ) is a two-step procedure. Initially, healthy cartilage is
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cartilage treatments. 15 Perifocal bone marrow oedema-like signals are a frequent finding after both chondral and osteochondral surgical procedures (e.g. microfracture, autologous chondrocyte implantation, osteochondral autograft or allograft
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disability subscales and high patient satisfaction after 24 months and 10-year follow-up ( 35 ). Cartilage implantation (regeneration) Autologous chondrocyte implantation (ACI) is a two-step procedure ( 36 ). Healthy chondrocytes are sampled from a
Institut du mouvement et de l’appareil locomoteur, Marseille, France
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autologous chondrocyte implantation (ACI) in cartilage defects of the medial femoral condyle with or without high tibial osteotomy in patients with varus deformity of less than 5° . Archives of Orthopaedic and Trauma Surgery 2013 133 43 – 49 . ( https
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marrow stimulation (microfractures), OATS, fresh osteochondral allograft, autologous chondrocyte implantation (ACI) and matrix-induced autologous chondrocyte implantation (MACI). This is a very unusual scenario for the paediatric–adolescent population and
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evidence-based systematic analysis . Am J Sports Med 2009 ; 37 : 2053 – 2063 . 70. Minas T Gomoll AH Rosenberger R Royce RO Bryant T . Increased failure rate of autologous chondrocyte implantation
Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
Berlin Institute of Health Center for Regenerative Therapies, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
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Berlin Institute of Health Center for Regenerative Therapies, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
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Trauma Orthopaedic Research Copenhagen Hvidovre (TORCH), Department of Orthopaedic Surgery, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
Berlin Institute of Health Center for Regenerative Therapies, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
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Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany
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that supports physiological bone formation via endochondral ossification by providing an organized pore network ( 62 ). Autologous chondrocyte implantation (ACI) also used as matrix-associated ACI (MACI), a cell-based approach (in the case of MACI