usually being treated with anticoagulants for cardiovascular or cerebrovascular diseases. As a matter of fact one-third of patients presenting with proximal femoral fractures are being anticoagulated at the same time. 3 This can have serious
Ioannis V. Papachristos and Peter V. Giannoudis
Marilena Giannoudi and Peter V Giannoudis
anticoagulants) in particular, approximately 2% of patients requiring HFS are taking DOACs ( 5 ). However, the intake of anticoagulation and antiplatelet medication can have an impact on the patients requiring hip fracture surgery (HFS). The need for reversal
Leonard Christianto Singjie, Reynaldo Halomoan, Ifran Saleh, Endrotomo Sumargono, and Erica Kholinne
Chest Physicians in 2012 recommended the administration of LMWH, unfractionated heparin, novel oral anticoagulant, and aspirin for VTE prophylaxis ( 8 ). The Scottish Intercollegiate Guidelines Network recommended the use of several notable
Rafik Yassa, Mahdi Yacine Khalfaoui, Ihab Hujazi, Hannah Sevenoaks, and Paul Dunkow
population. 1 Most of these patients are elderly with polypharmacy for multiple co-morbidities. 2 Many are likely to be taking some form of anticoagulant. In the United Kingdom, it has been estimated that 4% to 8% of these patients are on warfarin
Dimitrios A. Flevas, Panayiotis D. Megaloikonomos, Leonidas Dimopoulos, Evanthia Mitsiokapa, Panayiotis Koulouvaris, and Andreas F. Mavrogenis
effectiveness of anticoagulants may be enhanced by some mechanical methods. In particular, IPCDs stimulate endogenous fibrinolytic activity by reduction of plasminogen activator inhibitor-1 levels. 27 Disadvantages of mechanical VTE prophylaxis methods
Ioannis Ktistakis, Vasileios Giannoudis, and Peter V. Giannoudis
two parts. Part A focussed on the currently acceptable protocols of thromboprophylaxis in patients presenting with a hip fracture without taking any anticoagulant therapy for other medical conditions. Large-scale studies providing evidence of the
Marcel Niemann, Ellen Otto, Christian Eder, Yasmin Youssef, Lutz Kaufner, and Sven Märdian
thromboplastin time; aXa, anti factor Xa; BE, base excess; Lct, lactate; DOAC, directly acting oral anticoagulants; EC, erythrocyte concentrate; ECA, Ecarin chromogenic assay; FFP, fresh-frozen plasma; FVIII, coagulation factor VIII; FXIII, coagulation factor
Benedikt Johannes Braun, Jörg Holstein, Tobias Fritz, Nils Thomas Veith, Steven Herath, Philipp Mörsdorf, and Tim Pohlemann
-operative complication risk, the American College of Endocrinologists recommends a glucose level below 110 mg per decilitre. 18 Anticoagulant therapy Another often-underestimated risk factor in the geriatric population is treatment with anticoagulants. For
Stephanie Marrannes, Klaas Victor, Nele Arnout, Tine De Backer, Jan Victor, and Thomas Tampere
, vitamin K antagonists, non-vitamin K antagonist oral anticoagulants (NOACs), low dose unfractionated heparin and aspirin are valid options for thromboprophylaxis, with a preference for LMWH. 8 The 2011 guideline by the American Academy of Orthopaedic
Stefan Lazic, Oliver Boughton, Catherine F. Kellett, Deiary F. Kader, Loïc Villet, and Charles Rivière
-pharmacological (hydration, early mobilization, calf compression with stockings or an intermittent pneumatic compression device (IPCD)) and pharmacological means of prophylaxis (such as aspirin or anticoagulant drug). 46 , 47 The choice of which combination to use is
