Search Results

You are looking at 1 - 10 of 28 items for :

  • "anticoagulants" x
Clear All
Ioannis V. Papachristos Academic Department of Trauma & Orthopaedics, School of Medicine, University of Leeds, UK

Search for other papers by Ioannis V. Papachristos in
Google Scholar
PubMed
Close
and
Peter V. Giannoudis Academic Department of Trauma & Orthopaedics, School of Medicine, University of Leeds, UK
NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK

Search for other papers by Peter V. Giannoudis in
Google Scholar
PubMed
Close

usually being treated with anticoagulants for cardiovascular or cerebrovascular diseases. As a matter of fact one-third of patients presenting with proximal femoral fractures are being anticoagulated at the same time. 3 This can have serious

Open access
Marilena Giannoudi Department of Cardiology, Bradford Teaching Hospitals NHS Trust, Bradford, UK
Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK

Search for other papers by Marilena Giannoudi in
Google Scholar
PubMed
Close
and
Peter V Giannoudis Academic Department of Trauma and Orthopaedics, Floor D, Clarendon Wing, LGI, University of Leeds, Leeds, UK
NIHR Leeds Biomedical Research Centre, Chapel Allerton Hospital, Leeds, UK

Search for other papers by Peter V Giannoudis in
Google Scholar
PubMed
Close

anticoagulants) in particular, approximately 2% of patients requiring HFS are taking DOACs ( 5 ). However, the intake of anticoagulation and antiplatelet medication can have an impact on the patients requiring hip fracture surgery (HFS). The need for reversal

Open access
Leonard Christianto Singjie Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia
Faculty of Medicine, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

Search for other papers by Leonard Christianto Singjie in
Google Scholar
PubMed
Close
,
Reynaldo Halomoan Faculty of Medicine, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

Search for other papers by Reynaldo Halomoan in
Google Scholar
PubMed
Close
,
Ifran Saleh Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

Search for other papers by Ifran Saleh in
Google Scholar
PubMed
Close
,
Endrotomo Sumargono Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia

Search for other papers by Endrotomo Sumargono in
Google Scholar
PubMed
Close
, and
Erica Kholinne Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia
Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia

Search for other papers by Erica Kholinne in
Google Scholar
PubMed
Close

Chest Physicians in 2012 recommended the administration of LMWH, unfractionated heparin, novel oral anticoagulant, and aspirin for VTE prophylaxis ( 8 ). The Scottish Intercollegiate Guidelines Network recommended the use of several notable

Open access
Pelle V Wall University of California San Diego School of Medicine, Gilman Drive, La Jolla, California, United States of America

Search for other papers by Pelle V Wall in
Google Scholar
PubMed
Close
,
Brendon C Mitchell Department of Orthopaedic Surgery, University of California San Diego, West Arbor Drive, California, United States of America

Search for other papers by Brendon C Mitchell in
Google Scholar
PubMed
Close
,
Canhnghi N Ta Department of Orthopaedic Surgery, University of California San Diego, West Arbor Drive, California, United States of America

Search for other papers by Canhnghi N Ta in
Google Scholar
PubMed
Close
, and
William T Kent Department of Orthopaedic Surgery, University of California San Diego, West Arbor Drive, California, United States of America

Search for other papers by William T Kent in
Google Scholar
PubMed
Close

complications, and the development of pressure sores ( 11 , 12 , 13 , 14 , 15 ). Anticoagulation in hip fracture patients Chronic anticoagulant use is frequently seen in elderly hip fracture patients due to underlying cardiovascular disease ( 16

Open access
Rafik Yassa North West Deanery, Manchester, UK

Search for other papers by Rafik Yassa in
Google Scholar
PubMed
Close
,
Mahdi Yacine Khalfaoui North West Deanery, Manchester, UK

Search for other papers by Mahdi Yacine Khalfaoui in
Google Scholar
PubMed
Close
,
Ihab Hujazi North West Deanery, Manchester, UK

Search for other papers by Ihab Hujazi in
Google Scholar
PubMed
Close
,
Hannah Sevenoaks North West Deanery, Manchester, UK

Search for other papers by Hannah Sevenoaks in
Google Scholar
PubMed
Close
, and
Paul Dunkow Blackpool Victoria Teaching Hospitals, Blackpool, UK

Search for other papers by Paul Dunkow in
Google Scholar
PubMed
Close

population. 1 Most of these patients are elderly with polypharmacy for multiple co-morbidities. 2 Many are likely to be taking some form of anticoagulant. In the United Kingdom, it has been estimated that 4% to 8% of these patients are on warfarin

Open access
Dimitrios A. Flevas First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Search for other papers by Dimitrios A. Flevas in
Google Scholar
PubMed
Close
,
Panayiotis D. Megaloikonomos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Search for other papers by Panayiotis D. Megaloikonomos in
Google Scholar
PubMed
Close
,
Leonidas Dimopoulos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Search for other papers by Leonidas Dimopoulos in
Google Scholar
PubMed
Close
,
Evanthia Mitsiokapa First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Search for other papers by Evanthia Mitsiokapa in
Google Scholar
PubMed
Close
,
Panayiotis Koulouvaris First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Search for other papers by Panayiotis Koulouvaris in
Google Scholar
PubMed
Close
, and
Andreas F. Mavrogenis First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Search for other papers by Andreas F. Mavrogenis in
Google Scholar
PubMed
Close

effectiveness of anticoagulants may be enhanced by some mechanical methods. In particular, IPCDs stimulate endogenous fibrinolytic activity by reduction of plasminogen activator inhibitor-1 levels. 27 Disadvantages of mechanical VTE prophylaxis methods

Open access
Ioannis Ktistakis School of Medicine, University of Leeds, UK

Search for other papers by Ioannis Ktistakis in
Google Scholar
PubMed
Close
,
Vasileios Giannoudis School of Medicine, University of Leeds, UK

Search for other papers by Vasileios Giannoudis in
Google Scholar
PubMed
Close
, and
Peter V. Giannoudis School of Medicine, University of Leeds; National Institute for Health Research, Leeds Biomedical Research Unit, Leeds, UK

Search for other papers by Peter V. Giannoudis in
Google Scholar
PubMed
Close

two parts. Part A focussed on the currently acceptable protocols of thromboprophylaxis in patients presenting with a hip fracture without taking any anticoagulant therapy for other medical conditions. Large-scale studies providing evidence of the

Open access
Marcel Niemann Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany

Search for other papers by Marcel Niemann in
Google Scholar
PubMed
Close
,
Ellen Otto Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany

Search for other papers by Ellen Otto in
Google Scholar
PubMed
Close
,
Christian Eder Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

Search for other papers by Christian Eder in
Google Scholar
PubMed
Close
,
Yasmin Youssef Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany

Search for other papers by Yasmin Youssef in
Google Scholar
PubMed
Close
,
Lutz Kaufner Charité – Universitätsmedizin Berlin, Department of Anesthesiology and Intensive Care Medicine, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

Search for other papers by Lutz Kaufner in
Google Scholar
PubMed
Close
, and
Sven Märdian Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

Search for other papers by Sven Märdian in
Google Scholar
PubMed
Close

thromboplastin time; aXa, anti factor Xa; BE, base excess; Lct, lactate; DOAC, directly acting oral anticoagulants; EC, erythrocyte concentrate; ECA, Ecarin chromogenic assay; FFP, fresh-frozen plasma; FVIII, coagulation factor VIII; FXIII, coagulation factor

Open access
Benedikt Johannes Braun Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

Search for other papers by Benedikt Johannes Braun in
Google Scholar
PubMed
Close
,
Jörg Holstein Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

Search for other papers by Jörg Holstein in
Google Scholar
PubMed
Close
,
Tobias Fritz Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

Search for other papers by Tobias Fritz in
Google Scholar
PubMed
Close
,
Nils Thomas Veith Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

Search for other papers by Nils Thomas Veith in
Google Scholar
PubMed
Close
,
Steven Herath Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

Search for other papers by Steven Herath in
Google Scholar
PubMed
Close
,
Philipp Mörsdorf Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

Search for other papers by Philipp Mörsdorf in
Google Scholar
PubMed
Close
, and
Tim Pohlemann Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

Search for other papers by Tim Pohlemann in
Google Scholar
PubMed
Close

-operative complication risk, the American College of Endocrinologists recommends a glucose level below 110 mg per decilitre. 18 Anticoagulant therapy Another often-underestimated risk factor in the geriatric population is treatment with anticoagulants. For

Open access
Stephanie Marrannes Department of Orthopedic Surgery, Ghent University, Belgium

Search for other papers by Stephanie Marrannes in
Google Scholar
PubMed
Close
,
Klaas Victor Department of Orthopedic Surgery, University of Leuven, Belgium

Search for other papers by Klaas Victor in
Google Scholar
PubMed
Close
,
Nele Arnout Department of Orthopedic Surgery, Ghent University, Belgium

Search for other papers by Nele Arnout in
Google Scholar
PubMed
Close
,
Tine De Backer Department of Cardiology, Ghent University, Belgium

Search for other papers by Tine De Backer in
Google Scholar
PubMed
Close
,
Jan Victor Department of Orthopedic Surgery, Ghent University, Belgium

Search for other papers by Jan Victor in
Google Scholar
PubMed
Close
, and
Thomas Tampere Department of Orthopedic Surgery, Ghent University, Belgium

Search for other papers by Thomas Tampere in
Google Scholar
PubMed
Close

, vitamin K antagonists, non-vitamin K antagonist oral anticoagulants (NOACs), low dose unfractionated heparin and aspirin are valid options for thromboprophylaxis, with a preference for LMWH. 8 The 2011 guideline by the American Academy of Orthopaedic

Open access