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R J M Morrison, W G Fishley, K S Rankin, and M R Reed

been associated with a range of adverse post-operative outcomes ( 3 ), and there is a high incidence of deficiency reported in patients undergoing total hip (THR) or knee (TKR) arthroplasty ( 4 ). Previous systematic reviews ( 4 , 5 , 6 , 7 ) have

Cheuk Yin Li, Kenneth Jordan Ng Cheong Chung, Omar M. E. Ali, Nicholas D. H. Chung, and Cheuk Heng Li

Introduction Total knee replacement (TKR) is a cost-effective surgical procedure. 1 According to the national joint registry, 2 274,495 total knee replacements were performed in England, Wales, Northern Ireland and the Isle of Man in

Jason Trieu, Chris Schilling, Michelle M. Dowsey, and Peter F. Choong

Introduction The growing burden of knee osteoarthritis presents a significant challenge facing many communities. 1 Total knee replacement (TKR) remains the only definitive treatment option available for advanced arthritis, and this has

Vikki Wylde, Neil Artz, Nick Howells, and Ashley W. Blom

Introduction The primary reasons that patients elect to undergo total knee replacement (TKR) are to gain improvements in pain and walking ability. 1 However, patients often have high expectations of the outcome of their TKR and want more

Daniel J. McCormack, Darren Puttock, and Steven P. Godsiff

-rich plasma (PRP) or hyaluronic acid may be considered. Orthotic treatments such as a hinged offloader brace can also be employed. Operative management might involve a total knee replacement (TKR), with other options being a uni-compartmental knee replacement

Sohail Nisar, Jeya Palan, Charles Rivière, Mark Emerton, and Hemant Pandit

Introduction Over 100,000 total knee replacements (TKR) are performed annually for painful end-stage osteoarthritis (OA) in the UK. 1 The main reason for undertaking a TKR is to provide pain relief as well as improving function and

Leonard Christianto Singjie, Reynaldo Halomoan, Ifran Saleh, Endrotomo Sumargono, and Erica Kholinne

Introduction Patients undergoing major orthopedic surgeries, such as total hip replacement (THR), total knee replacement (TKR), and trauma surgery (hip/femur fracture), are at an elevated risk of venous thromboembolism (VTE). Deep vein

Anoop K. Prasad, Jaimee H.S. Tan, Hany S. Bedair, Sebastian Dawson-Bowling, and Sammy A. Hanna

  • Over 100,000 total knee replacements (TKRs) are carried out in the UK annually, with cemented fixation accounting for approximately 95% of all primary TKRs. In Australia, 68.1% of all primary TKRs use cemented fixation, and only 10.9% use cementless fixation. However, there has been a renewed interest in cementless fixation as a result of improvements in implant design and manufacturing technology.

  • This meta-analysis aimed to compare the outcomes of cemented and cementless fixation in primary TKR. Outcome measures included the revision rate and patient-reported functional scores.

  • MEDLINE and EMBASE were searched from the earliest available date to November 2018 for randomized controlled trials of primary TKAs comparing cemented versus cementless fixation outcomes.

  • Six studies met our inclusion criteria and were analysed. A total of 755 knees were included; 356 knees underwent cemented fixation, 399 underwent cementless fixation. They were followed up for an average of 8.4 years (range: 2.0 to 16.6).

  • This study found no significant difference in revision rates and knee function in cemented versus cementless TKR at up to 16.6-year follow-up.

Cite this article: EFORT Open Rev 2020;5:793-798. DOI: 10.1302/2058-5241.5.200030

E. Carlos Rodríguez-Merchán

young haemophilic patient to avoid or delay total knee replacement (TKR). The operation may give the patient years of life without pain. 26 The most commonly used procedure in advanced knee haemophilic arthropathy is TKR ( Figs. 6 and 7 ). However

James R. Berstock, James R. Murray, Michael R. Whitehouse, Ashley W. Blom, and Andrew D. Beswick

Introduction Although several surgical approaches to the knee exist, the medial parapatellar approach has been used in 93% of primary total knee replacements (TKRs) performed in England and Wales between 2004 and 2014. 1 This approach