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Low-dose dexamethasone during arthroplasty

What do we know about the risks?

Jessica T. Wegener Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Tim Kraal Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Markus F. Stevens Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Markus W. Hollmann Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Gino M.M.J. Kerkhoffs Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Daniël Haverkamp Department of Orthopedic Surgery, Slotervaart Ziekenhuis, Amsterdam, The Netherlands

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substantial part of the shortened hospital stay is related to improved peri-operative pain management and prevention of post-operative nausea and vomiting (PONV), resulting in faster mobilisation and discharge of patients. Meanwhile, many peri

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Qiuyuan Wang Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China
Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Feng Li Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Yidan Yang Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Chen Yue Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Jiayi Guo Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China
Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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was assessed by knee range of motion, daily mobilization distance, and time to first straight leg raising. Additionally, we assessed the LOS and major surgical complications (postoperative nausea or vomiting (PONV), wound complications, deep vein

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Felix Christoph Finger BG Klinik Tübingen, Department of Traumatology and Reconstructive Surgery, Eberhard Karls University of Tübingen, Tübingen, Germany

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Steffen Schröter Diakonie Klinikum Jung-Stilling GmbH, Department of Trauma and Reconstructive Surgery, Siegen, Germany
Osteotomie Komitee der Deutschen Knie Gesellschaft (DKG), Munich, Germany

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Christoph Ihle BG Klinik Tübingen, Department of Traumatology and Reconstructive Surgery, Eberhard Karls University of Tübingen, Tübingen, Germany

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Moritz Herbst BG Klinik Tübingen, Department of Traumatology and Reconstructive Surgery, Eberhard Karls University of Tübingen, Tübingen, Germany

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Tina Histing BG Klinik Tübingen, Department of Traumatology and Reconstructive Surgery, Eberhard Karls University of Tübingen, Tübingen, Germany

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Marc-Daniel Ahrend BG Klinik Tübingen, Department of Traumatology and Reconstructive Surgery, Eberhard Karls University of Tübingen, Tübingen, Germany
Osteotomie Komitee der Deutschen Knie Gesellschaft (DKG), Munich, Germany
AO Research Institute Davos, Davos, Switzerland

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following medial open-wedge HTO ( 17 ). To prevent PONV (postoperative nausea and vomiting), all patients received 4 mg dexamethasone. Pehora et al. showed in their Cochrane Review, that Dexamethasone administration can prolong the duration of

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