Olga D. Savvidou
Olga D. Savvidou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panagiotis Koutsouradis
Panagiotis Koutsouradis
Department of Orthopaedic Surgery, Mediterraneo Hospital, Athens, Greece
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Ioanna K. Bolia
Ioanna K. Bolia
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Angelos Kaspiris
Angelos Kaspiris
Laboratory of Molecular Pharmacology/Sector for Bone Research, School of Health Sciences, University of Patras, Patras 26504, Greece
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George D. Chloros
George D. Chloros
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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disorder of the synovium characterized by the formation of multiple cartilaginous nodules in the synovium, many of which detach creating loose bodies. When the lesion occurs in the upper limb it has a predilection for the elbow followed by the shoulder. 5
Bogdan Serban
Bogdan Serban
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Bogdan Cretu
Bogdan Cretu
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Adrian Cursaru
Adrian Cursaru
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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Cornelia Nitipir
Cornelia Nitipir
Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania
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Elias University Emergency Hospital, Bucharest, Romania
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Cristina Orlov-Slavu
Cristina Orlov-Slavu
Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania
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Elias University Emergency Hospital, Bucharest, Romania
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Catalin Cirstoiu
Catalin Cirstoiu
Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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a previously irradiated region make management of the local recurrence challenging. Even in the presence of recurring illness, limb salvage therapy is becoming increasingly popular, with an emphasis on maintaining extremity function and quality of
Olga D. Savvidou
Olga D. Savvidou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panagiotis Koutsouradis
Panagiotis Koutsouradis
Department of Orthopaedic Surgery, 417 Veterans Hospital (NIMTS), Athens, Greece
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George D. Chloros
George D. Chloros
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Ioannis Papanastasiou
Ioannis Papanastasiou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Thomas Sarlikiotis
Thomas Sarlikiotis
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Aggelos Kaspiris
Aggelos Kaspiris
Laboratory of Molecular Pharmacology/ Sector for Bone Research, School of Health Sciences, University of Patras, Patras, Greece
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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excellent elbow function and the upper extremity was growing without deformity. 93 Recently, Graci et al presented the case of a 12-year-old girl with parosteal osteosarcoma of the right distal humerus treated with en bloc resection, intraoperative
Maria A. Smolle
Maria A. Smolle
Department of Orthopaedics and Trauma, Medical University of Graz, Austria
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Dimosthenis Andreou
Dimosthenis Andreou
Department of General Orthopaedics and Tumour Orthopaedics, University Hospital Muenster, Germany
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Per-Ulf Tunn
Per-Ulf Tunn
Tumour Orthopaedics, HELIOS Klinikum Berlin-Buch, Germany
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Andreas Leithner
Andreas Leithner
Department of Orthopaedics and Trauma, Medical University of Graz, Austria
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wrapped spirally around the proximal site of the total femur in 12 patients – hip dislocation rate lower in patients with LARS-augmentation and active range of motion (ROM) as well as limb function better in this cohort – infection rates similar (1/12 for
Catalin Cirstoiu
Catalin Cirstoiu
Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Bogdan Cretu
Bogdan Cretu
Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Sergiu Iordache
Sergiu Iordache
Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Mihnea Popa
Mihnea Popa
Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Bogdan Serban
Bogdan Serban
Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Adrian Cursaru
Adrian Cursaru
Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Non-surgical treatment Table 2 Surgical treatment of upper limb metastatic disease of the bone. Anatomical location Single metastasis (fractured or not) Multiple metastases All types of metastases Impending
Chengxiang Li
Chengxiang Li
Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
University of Basel, Basel, Switzerland
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University of Basel, Basel, Switzerland
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Fatime Krasniqi
Fatime Krasniqi
Department of Oncology, University Hospital Basel, Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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Ricardo Donners
Ricardo Donners
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Department of Radiology, University Hospital Basel, Basel, Switzerland
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Department of Radiology, University Hospital Basel, Basel, Switzerland
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Christoph Kettelhack
Christoph Kettelhack
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland
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Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland
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Andreas H Krieg
Andreas H Krieg
Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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features differed according to tumor location. SSs were most commonly mistaken for neurogenic tumors in the upper limbs (56%) and cystic masses in the lower limbs (47%) ( 10 ). This happened because the relatively small-sized SS tended to be more homogenous
Miklós Szendrői
Miklós Szendrői
Department of Orthopaedics, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary
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Imre Antal
Imre Antal
Department of Orthopaedics, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary
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Attila Szendrői
Attila Szendrői
Department of Urology, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary
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Áron Lazáry
Áron Lazáry
National Center for Spinal Disorders, H-1126 Budapest, Királyhágó u.1., Hungary
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Péter Pál Varga
Péter Pál Varga
National Center for Spinal Disorders, H-1126 Budapest, Királyhágó u.1., Hungary
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-sensitivity, the radiosensitivity, the metastatic load and the general status of the patient, available and effective drugs, etc. Not all impending fractures, especially not those of non-weight-bearing bones of the upper extremity, must be operated on as
Irina-Anca Eremia
Irina-Anca Eremia
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania
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Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania
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Bogdan Serban
Bogdan Serban
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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Mihnea Popa
Mihnea Popa
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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Adela Iancu
Adela Iancu
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
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Silvia Nica
Silvia Nica
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania
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Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania
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Catalin Cirstoiu
Catalin Cirstoiu
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania
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preserve kidney function as much as possible. This approach is supported by evidence that shows substantial survival advantages from both partial and radical nephrectomy in patients with localized disease ( 4 ). In situations where surgery poses a high
Antal Imre
Antal Imre
Department of Orthopaedics, Semmelweis University, Budapest, Hungary
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Sápi Zoltán
Sápi Zoltán
Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest
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Szendrői Miklós
Szendrői Miklós
Department of Orthopaedics, Semmelweis University, Budapest, Hungary
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, which is an essential mediator for recruitment, formation, enhanced function and survival of osteoclast-like giant cells. For this effect, RANKL interacts with the RANK on the surface of giant cells. This interaction is prevented by denosumab as it binds
