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Junbo He Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China
These authors contributed equally to this work and should be considered co-first authors

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Tingkui Wu Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China
These authors contributed equally to this work and should be considered co-first authors

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Chen Ding Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China

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Beiyu Wang Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China

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Ying Hong West China School of Nursing, Sichuan University/ Department of Anesthesia and Operation Center, West China Hospital, Sichuan University, Chengdu, China

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Hao Liu Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China

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Adjacent level intradiscal pressure and segmental kinematics following a cervical total disc arthroplasty-An in vitro human cadaveric mode Dmitriev, AE 212 13.3 V 44 A prospective, randomized, controlled cervical fusion study using

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xueli Yan Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Han Zhang Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Wenjun Pan Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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.cger.2019.03.001 ) 5. Ross D Erkocak O Rasouli MR & Parvizi J . Operative time directly correlates with blood loss and need for blood transfusion in total joint arthroplasty . Archives of Bone and Joint Surgery 2019 7 229 – 234 . 6. Liu ZG

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Eduardo Moreira Pinto Orthopaedic and Traumatology Surgery, Spine Division, Entre Douro e Vouga Hospital Center, Santa Maria da Feira, Portugal

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Artur Teixeira Orthopaedic and Traumatology Surgery, Spine Division, Entre Douro e Vouga Hospital Center, Santa Maria da Feira, Portugal

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Ricardo Frada Orthopaedic and Traumatology Surgery, Spine Division, Entre Douro e Vouga Hospital Center, Santa Maria da Feira, Portugal

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Pedro Atilano Orthopaedic and Traumatology Surgery, Spine Division, Entre Douro e Vouga Hospital Center, Santa Maria da Feira, Portugal

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António Miranda Orthopaedic and Traumatology Surgery, Spine Division, Entre Douro e Vouga Hospital Center, Santa Maria da Feira, Portugal

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degeneration and disease after arthrodesis and total disc arthroplasty . Spine 2008 ; 33 : 1701 – 1707 . 11. Lee JC Lee S-H Peters C Riew KD . Adjacent segment pathology requiring reoperation after anterior cervical arthrodesis: the

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Chaojun Shen Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Tongyou Qu Department of Pharmacy, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang China

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Lin Chen Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yue Sun Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang China

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other indications . Drugs 1999 57 1005 – 1032 . ( https://doi.org/10.2165/00003495-199957060-00017 ) 3. Wind TC Barfield WR & Moskal JT . The effect of tranexamic acid on transfusion rate in primary total hip arthroplasty . Journal of

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xuelei Zhang Department of Ultrasound, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Chengxin Xie Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Department of Endocrinology, Ministry of Education, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China
Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Luxia Wu Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Guoping Cai Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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thrombogenic biomarkers in total knee arthroplasty: study protocol . BMJ Open 2021 11 e038399 . ( https://doi.org/10.1136/bmjopen-2020-038399 ) 13 Emrah K Ali AH Utku O Murat K Kenan S & Deniz B . Efficacy of tranexamic acid on blood loss in

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Juan Manuel Henríquez-Jurado Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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María Catalina Osuna-Pérez Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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Héctor García-López Department of Nursing, Physiotherapy and Medicine. University of Almería. Ctra Sacrament s/n, Almería, Spain

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Rafael Lomas-Vega Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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María del Carmen López-Ruiz Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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Esteban Obrero-Gaitán Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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Irene Cortés-Pérez Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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therapeutic option to add to physiotherapy programs. There has been an increase in the creation and use of virtual reality hardware and software in physical rehabilitation, which has shown to be effective in pathologies such as total knee arthroplasty ( 25

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Paulo Diogo Cunha Orthopedic Surgery Department, Hospital de Braga, Portugal

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Tiago P Barbosa Orthopedic Surgery Department, Hospital de Braga, Portugal

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Guilherme Correia Orthopedic Surgery Department, Hospital de Braga, Portugal

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Rafaela Silva Anesthesiology Department, Hospital de Braga, Portugal

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Nuno Cruz Oliveira Orthopedic Surgery Department, Hospital de Braga, Portugal

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Pedro Varanda Orthopedic Surgery Department, Hospital de Braga, Portugal
Life and Health Science Research Institute, University of Minho, Portugal

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Bruno Direito-Santos Orthopedic Surgery Department, Hospital de Braga, Portugal
Life and Health Science Research Institute, University of Minho, Portugal

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discectomy and intervertebral fusion, intervertebral arthroplasty and vertebral corpectomy. The osseous vertebral anatomy is widely accessed through an natural corridor, allowing for the longitudinal manipulation from C1 to C7 in the treatment of degenerative

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Tiago P Barbosa Hospital de Braga E.P.E., Braga, Portugal

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Ana Rita Raposo Hospital de Braga E.P.E., Braga, Portugal

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Paulo Diogo Cunha Hospital de Braga E.P.E., Braga, Portugal

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Nuno Cruz Oliveira Hospital de Braga E.P.E., Braga, Portugal

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Armanda Lobarinhas Hospital de Braga E.P.E., Braga, Portugal

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Pedro Varanda Hospital de Braga E.P.E., Braga, Portugal

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Bruno Direito-Santos Hospital de Braga E.P.E., Braga, Portugal

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Introduction Overall, the indications for operating on spinal disorders are increasing as reflected by the total number of spine surgeries. Spine surgery usually involves decompression and/or fusion of one or more spine levels ( 1 , 2 , 3

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