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customized implants to handle complex reconstructions. This topic is closely related to computer-assisted surgery (CAS) and the optimization of data derived from preoperative imaging studies for the improvement of clinical and surgical outcomes such as the
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by way of biomimetic surface functionalization (lotus effect, dragonfly wings). 22 , 23 Computer-assisted surgery in the form of custom, individual patient instruments or computerized intra-operative guidance has been proposed as an effective way