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Maria A. Smolle Department of Orthopaedics and Trauma, Medical University of Graz, Austria

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Dimosthenis Andreou Department of General Orthopaedics and Tumour Orthopaedics, University Hospital Muenster, Germany

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Per-Ulf Tunn Tumour Orthopaedics, HELIOS Klinikum Berlin-Buch, Germany

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Andreas Leithner Department of Orthopaedics and Trauma, Medical University of Graz, Austria

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tumours were risk factors for instability. 10 The only protective factor against hip instability was a posterolateral approach. 10 Moreover, the authors concluded that a posterolateral approach, together with application of a synthetic device for

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Stephanie Marrannes Department of Orthopedic Surgery, Ghent University, Belgium

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Klaas Victor Department of Orthopedic Surgery, University of Leuven, Belgium

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Nele Arnout Department of Orthopedic Surgery, Ghent University, Belgium

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Tine De Backer Department of Cardiology, Ghent University, Belgium

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Jan Victor Department of Orthopedic Surgery, Ghent University, Belgium

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Thomas Tampere Department of Orthopedic Surgery, Ghent University, Belgium

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populations. 1 , 23 – 27 Increased bleeding with factor Xa inhibitors compared to aspirin and LMWH was also reported by Lindquist et al, and a meta-analysis by Venker et al reported a significantly higher risk of major bleeding events with factor Xa

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Julie J. Willeumier Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Yvette M. van der Linden Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Michiel A.J. van de Sande Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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P.D. Sander Dijkstra Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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careful balance between the advantages of a prophylactic treatment versus the risks of surgery and disadvantages of over-treatment for the patient has to be made. Multiple different factors for an impending fracture have been described, such as pain

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Miklós Szendrői Department of Orthopaedics, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary

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Imre Antal Department of Orthopaedics, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary

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Attila Szendrői Department of Urology, Semmelweis University, H-1082 Budapest, Üllői 78/b, Hungary

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Áron Lazáry National Center for Spinal Disorders, H-1126 Budapest, Királyhágó u.1., Hungary

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Péter Pál Varga National Center for Spinal Disorders, H-1126 Budapest, Királyhágó u.1., Hungary

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. 28 Risk factors for developing a bone metastasis were tumour size (> 5 cm), higher tumour grade, sub-type of the tumour (lobular carcinoma) and number of positive lymph nodes. For those patients with metastases in the bone, factors influencing

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Ajay Puri Department of Surgery, Tata Memorial Hospital, HBNI, Mumbai

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. Fiorenza F Abudu A Grimer RJ et al. Risk factors for survival and local control in chondrosarcoma of bone . J Bone Joint Surg Br 2002 ; 84 : 93 – 99 . 2. Gerrand C Athanasou N Brennan B et al

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Zsombor Panti Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Mihai Nica Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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advantage suggested by this categorization is an easier identification of risk factors and elements which can be addressed for improvement of the overall results. Table 1. Modular endoprothetic failure classification Main category Failure

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Maria Anna Smolle Medical University of Graz, Austria

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Dimosthenis Andreou Münster University Hospital, Germany

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Per-Ulf Tunn Sarcoma Center Berlin-Brandenburg, HELIOS Klinikum Berlin-Buch, Germany

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Joanna Szkandera Medical University of Graz, Austria

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Bernadette Liegl-Atzwanger Medical University of Graz, Austria

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Andreas Leithner Medical University of Graz, Austria

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Italiano A Le Cesne A Mendiboure J . Prognostic factors and impact of adjuvant treatments on local and metastatic relapse of soft-tissue sarcoma patients in the competing risks setting . Cancer 2014 ; 120 : 3361 - 3369 . 15

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Chengxiang Li Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
University of Basel, Basel, Switzerland

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Fatime Krasniqi Department of Oncology, University Hospital Basel, Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland

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Ricardo Donners The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Department of Radiology, University Hospital Basel, Basel, Switzerland

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Christoph Kettelhack The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland

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Andreas H Krieg Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland

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chemotherapy based on ifosfamide had an impressive response to treatment of metastatic and pediatric SS, SS was considered to be a particularly chemosensitive STS ( 70 , 71 ). In general, chemotherapy is reserved for patients with high-risk tumors or advanced

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Bogdan Serban Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Adrian Cursaru Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Cornelia Nitipir Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania

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Cristina Orlov-Slavu Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania

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Catalin Cirstoiu Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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in metastatic disease. This second approach is initially more costly and causes a greater loss of function, but the probability of local recurrence is lower. Even though local recurrences do not increase the risk of metastasis, they do require further

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Irina-Anca Eremia Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania

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Mihnea Popa Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania

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Adela Iancu Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

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Silvia Nica Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania

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carcinoma: epidemiologic trends, survival, and clinical risk factors using a population-based cohort . European Urology Focus 2019 5 474 – 481 . ( https://doi.org/10.1016/j.euf.2017.12.007 ) 94 Survival Rates for Kidney Cancer [Internet]. [cited 2023 Jun

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