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Gherardo Pagliazzi Department of Paediatric Orthopaedics, University of Basel Children’s Hospital, Basel, Switzerland
Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Enrico De Pieri Laboratory for Movement Analysis, University of Basel Children’s Hospital, Basel, Switzerland
Department of Biomedical Engineering, University of Basel, Basel, Switzerland

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Michèle Kläusler Department of Paediatric Orthopaedics, University of Basel Children’s Hospital, Basel, Switzerland

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Morgan Sangeux Laboratory for Movement Analysis, University of Basel Children’s Hospital, Basel, Switzerland
Murdoch Children’s Research Institute, Melbourne, Victoria, Australia
The University of Melbourne, Melbourne School of Engineering, Melbourne, Victoria, Australia

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Elke Viehweger Department of Paediatric Orthopaedics, University of Basel Children’s Hospital, Basel, Switzerland
Laboratory for Movement Analysis, University of Basel Children’s Hospital, Basel, Switzerland
Department of Biomedical Engineering, University of Basel, Basel, Switzerland

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anteversion (FNA), squinting patella, and excessive external tibial rotation, has been considered as a risk factor in the onset of overuse injuries, especially the PFPS ( 23 ). Studies combining 3D gait analysis and musculoskeletal modelling have shown that

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Alessandro Sangiorgio Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Martina Sirone Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Federico Maria Adravanti Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland
2nd Orthopaedic and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Enrique Adrian Testa Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland
Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland

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Martin Riegger Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland
Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland

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Giuseppe Filardo Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland
2nd Orthopaedic and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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that independent risk factors for AT and ATR during fluoroquinolone treatment are patient’s age over 60 years, renal failure, organ transplantation, immunodeficiency, and the association with concomitant corticosteroid use ( 12 , 46 ). When these

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Bart A Swierstra Medical Guidelines, Amsterdam, The Netherlands

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W Annefloor van Enst Medical Guidelines, Amsterdam, The Netherlands

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questions: What is the incidence of radiographic osteoarthritis in adults after an ankle fracture? How long does the risk of radiological osteoarthritis persist since the accident? Which prognostic factors are related to the development of

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José Nuno Ferreira Department of Orthopaedics, Hospital Beatriz Ângelo, Portugal

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João Vide Department of Orthopaedics, Hospital Beatriz Ângelo, Portugal

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Daniel Mendes Department of Orthopaedics, Hospital Beatriz Ângelo, Portugal

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João Protásio Department of Orthopaedics, Hospital Beatriz Ângelo, Portugal

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Rui Viegas Department of Orthopaedics, Hospital Beatriz Ângelo, Portugal

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Manuel Resende Sousa Department of Orthopaedics, Hospital da Luz, Portugal

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in the tibia, which are significantly correlated with CAI and could, therefore, be considered intrinsic risk factors for CAI after an ankle sprain. 15 Other factors such as a frontal curvature ≥ 2 mm, and an anterior position of the talar centre

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Nikolaos Gougoulias Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Hesham Oshba Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Apostolos Dimitroulias Jacobi Medical Center – Trauma Unit – Bronx, New York, USA

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Anthony Sakellariou Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Alexander Wee Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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approximately 15% in matched control groups of non-diabetic patients. 1 , 3 – 5 A recent large-scale study showed that diabetes mellitus (DM) had the highest odds for amputation after ankle fracture fixation, compared to any other risk factors, 6

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Manuel Monteagudo Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Pilar Martínez de Albornoz Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Borja Gutierrez Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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José Tabuenca Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Ignacio Álvarez Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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understanding the mechanical disturbance caused by plantar fasciotomy, to understanding pathomechanics with risk factors predisposing to PF. Thus, proximal plantar fasciotomy has also given way to gastrocnemius recession as the most common surgical procedure for

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Mustafa S. Rashid Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK

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Yves Tourné Institut Grenoblois de Chirurgie du Pied, Echirolles, France

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Kar H. Teoh Princess Alexandra Hospital, Harlow, UK

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challenges to conducting such research. Several confounders can be accounted for, whilst others may not. Randomization sequences may include stratification for certain factors, to reduce the risk they may impact the primary outcome. Such factors may include

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Andreas F. Mavrogenis First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Panayiotis D. Megaloikonomos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Thekla Antoniadou First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Vasilios G. Igoumenou First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Georgios N. Panagopoulos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Leonidas Dimopoulos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Konstantinos G. Moulakakis Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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George S. Sfyroeras Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Andreas Lazaris Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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-ischaemic. 1 , 3 , 10 Sensorimotor and sympathetic diabetic neuropathy are major risk factors for DFUs. 10 , 12 Sensory neuropathy leads to loss of pain, pressure and temperature sensation; in this setting, trauma, even minor, ulceration or infection is

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Stefan Rammelt University Center of Orthopaedics & Traumatology, University Hospital Carl Gustav Carus, Dresden, Germany

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complication by a factor of 4 in diabetics. 11 In addition, more than 40% of diabetic patients also present with peripheral arterial disease. 15 Obesity has been identified as an independent risk factor for complications and poorer outcomes in both

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Sohail Yousaf Kingston Hospital NHS Foundation Trust, UK
University of Brighton, UK

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Edward J.C. Dawe Western Sussex Hospitals NHS Foundation Trust, UK
Brighton and Sussex Medical Schools, UK

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Alan Saleh Kingston Hospital NHS Foundation Trust, UK

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Ian R. Gill Kingston Hospital NHS Foundation Trust, UK

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Alex Wee Frimley Health NHS Foundation Trust, UK

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optimizing diabetic control and other risk factors such as smoking and nutritional status. In addition, its aim is to identify patients at risk for further fractures requiring off-loading and management of bone disease with medical or surgical treatment. This

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