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Maria Tennyson Department of Trauma & Orthopaedic Surgery, Cambridge University Hospital, Cambridge, UK

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Matija Krkovic Department of Trauma & Orthopaedic Surgery, Cambridge University Hospital, Cambridge, UK

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Mary Fortune The Department of Public Health & Primary Care, Strangeways Research Laboratory, Cambridge, UK

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Ali Abdulkarim Department of Trauma & Orthopaedic Surgery, Cambridge University Hospital, Cambridge, UK

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alone, or the method of using IM nails with poller screws is more advantageous as there is a paucity of data comparing the efficacy of the latter treatment. Therefore, we conducted this systematic review to provide more comprehensive and reliable

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James R. Berstock University of British Colombia Department of Orthopaedics, Gordon & Leslie Diamond Health Care Centre, Vancouver, British Columbia, Canada

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Michael R. Whitehouse Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Southmead Hospital, Bristol, UK
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, UK

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popularity and became the most commonly performed orthopaedic surgery in all countries collecting such data. Subsequent trials that confirmed the findings of the NEJM publication were conducted, published and largely ignored. 2 It took a review of the

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Allan Roy Sekeitto Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Nkhodiseni Sikhauli Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Dick Ronald van der Jagt Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Lipalo Mokete Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Jurek R.T. Pietrzak Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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, and limited outcomes. 33 A systematic review reported worse mobility scores, pain scores and mortality rates in non-operative treatment. 32 ii) Operative treatment Optimal surgical management of displaced FNFs especially in the elderly

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Claudio Rosso ARTHRO Medics, Shoulder and Elbow Center, Basel, Switzerland
University of Basel, Basel, Switzerland
Swiss Orthopaedics, Grandvaux, Switzerland

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Mark E Morrey Swiss Orthopaedics, Grandvaux, Switzerland

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Michael O Schär Swiss Orthopaedics, Grandvaux, Switzerland

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Kushtrim Grezda ARTHRO Medics, Shoulder and Elbow Center, Basel, Switzerland
University of Basel, Basel, Switzerland
Department of Orthopedic Surgery, Division of Shoulder and Elbow, Mayo Clinic, Rochester, Minnesota

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the Swiss Orthopaedics Shoulder Elbow and Expert Group †
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the Swiss Orthopaedics Shoulder Elbow and Expert Group

, chronicity and stage of the disorder in the shoulder. Therefore, we aim to critically review the efficacy of PRP in shoulder disorders with a special focus on its use in the treatment of rotator cuff disorders. Preparation, classification and

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Chaojun Shen Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Tongyou Qu Department of Pharmacy, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang China

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Lin Chen Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yue Sun Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang China

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also head and neck surgery ( 5 ) and cardiac surgery ( 6 , 7 ). A systematic review identified 28 trials that compared topical TXA in surgical patients (cardiac, thoracic, spinal, knee, or head and neck surgery) with no TXA or placebo ( 8 ). Blood loss

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Jie Xiang Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Weibo Zhao Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xiao Luo Department of Radiology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Zhenghua Hong Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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by the severity of neurologic deficits, the influence of early cardiovascular changes secondary to SSDH cannot be ignored. Herein, we reported a case of a patient with acute SSDH and presenting with Takotsubo cardiomyopathy (TTC) and reviewed the

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Pierre Hoffmeyer Editor-in-Chief, EFORT Open Reviews

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benefitted from the interaction of surgical and scientific activities all around the world. This is especially true for our Journal with its high-quality reviews from all continents. An author’s work from Asia will be analysed by a reviewer in South America

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James R. Berstock Musculoskeletal Research Unit, University of Bristol, UK

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James R. Murray Avon Orthopaedic Centre, Southmead Hospital, Bristol, UK

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Michael R. Whitehouse Musculoskeletal Research Unit, University of Bristol, UK

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Ashley W. Blom Musculoskeletal Research Unit, University of Bristol, UK

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Andrew D. Beswick Musculoskeletal Research Unit, University of Bristol, UK

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and largely fail to demonstrate clinically relevant differences. Previous reviews of this topic have compared the medial parapatellar approach with a combination of the quadriceps sparing approaches (midvastus, mini-midvastus and subvastus together

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Pengqiang Lou Liaoning University of Traditional Chinese Medicine, Shenyang, China

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Guangzhi Zhou Liaoning University of Traditional Chinese Medicine, Shenyang, China

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Bo Wei Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China

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Xiaolei Deng Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China

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Decai Hou Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China

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article provides a review of the pathophysiology of the sclerotic zone in femoral head necrosis, the formation process, and the impact on femoral head necrosis. Pathology of femoral head necrosis and sclerotic zone formation The death of bone

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Xinhui Wu Department of Orthopedics, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China

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Xiaoxin Fang Department of Endocrinology and Metabolism, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China

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Feng Lu Nanjing Medical University, Jiangning, Nanjing, China

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Qiong Chen Jinhua TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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Junjian Liu Department of Orthopedics, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China

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Longpo Zheng Department of Orthopedics, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
Orthopedic Intelligent Minimally Invasive Diagnosis and Treatment Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China

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, cytoplasmic swelling, and mitochondrial condensation ( 2 , 8 ). In recent years, numerous studies have demonstrated that ferroptosis plays an important role in the progression of OP. This review shows the role of iron metabolism, lipid metabolism, and the

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