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Donald J. Davidson Research Department of Orthopaedics and Musculoskeletal Sciences, University College London, London, UK
Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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David Spratt Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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Alexander D. Liddle Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK
MSK Lab, Imperial College London, London, UK

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Introduction Prosthetic joint infection (PJI) is one of the most feared complications of arthroplasty surgery due to its resistance to therapy with existing antibiotics. 1 It is a major cause of failure in arthroplasty, being the leading

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Pablo A. Slullitel Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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José I. Oñativia Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Martin A. Buttaro Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Marisa L. Sánchez Infectology Department, Italian Hospital of Buenos Aires, Argentina

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Fernando Comba Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Gerardo Zanotti Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Francisco Piccaluga Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Introduction Being the third most common cause of revision surgery following primary total hip arthroplasty (THA), peri-prosthetic joint infection (PJI) constitutes one of the most undesired complications, with a prevalence of 0.3% to 2

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J R W Crutsen Department of Orthopaedic Surgery, VieCuri Medical Center, Venlo, the Netherlands

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M C Koper Department of Orthopaedic Surgery, Reinier HAGA Orthopaedic Center, Zoetermeer, the Netherlands

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J Jelsma Department of Orthopaedic Surgery and Traumatology, Zuyderland Medical Center, Sittard-Geleen-Heerlen, the Netherlands

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M Heymans Zuyderland Academy, Centre of Knowledge and Information (KIC), Zuyderland Medical Centre, Sittard-Geleen, the Netherlands

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I C Heyligers Department of Orthopaedic Surgery and Traumatology, Zuyderland Medical Center, Sittard-Geleen-Heerlen, the Netherlands
School of Health Professions Education (SHE), Maastricht University, Maastricht, the Netherlands

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B Grimm Luxembourg Institute Health, Human Motion, Orthopaedics, Sports Medicine, Digital Methods (HOSD), Luxembourg, Luxembourg

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N M C Mathijssen Department of Orthopaedic Surgery, Reinier HAGA Orthopaedic Center, Zoetermeer, the Netherlands

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M G M Schotanus Department of Orthopaedic Surgery and Traumatology, Zuyderland Medical Center, Sittard-Geleen-Heerlen, the Netherlands
School of Care and Public Health Research Institute (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands

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debris (ARMD) ( 1 , 2 , 3 , 4 ). There is also an increasing number of case reports describing systemic reactions in relation to elevated blood cobalt concentrations known as prosthetic hip-associated cobalt toxicity (PHACT) ( 5 , 6 ). Increased

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Andy Craig Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK

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S W King Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK

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B H van Duren Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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V T Veysi Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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S Jain Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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J Palan Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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Joint Registry (NJR) data indicating 10-year revision rates of approximately 2% for a number of commonly used prostheses ( 6 ). Nonetheless, prosthetic joint infection (PJI) remains a devastating complication. Of all single- and first-stage revisions (of

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Bengt Mjöberg Department of Orthopaedics, Lund University, Lund, Sweden

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Introduction Minor prosthetic migration as detected by radiostereometric analysis (RSA) 1 – with a detection limit of 0.1–0.2 mm – is sometimes seen as unrelated to loosening since such prosthetic components usually remain asymptomatic

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William G. Blakeney Department of Surgery, CIUSSS-de-L’Est-de-L’Ile-de-Montréal, Hôpital Maisonneuve Rosemont, Montréal, Québec, Canada
Department of Surgery, Albany Health Campus, Albany, Australia

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Jean-Alain Epinette Clinique Médico-chirurgicale, Bruay la Buissière, France

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Pascal-André Vendittoli Department of Surgery, Albany Health Campus, Albany, Australia
Department of Surgery, Université de Montréal, Montréal, Québec, Canada

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personalized medicine, we aim to reproduce the patient’s native anatomy and the physiological articular environment, aiming to improve prosthetic kinematics and restoring normal function. Our new quest is to offer a forgotten hip joint to our patients

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Pablo Castillón Department of Trauma and Orthopaedic Surgery, Hospital, Universitari Mútua Terrassa, Terrassa, Barcelona, Spain
Universidad Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain

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Josep Maria Muñoz Vives Department of Trauma and Orthopaedic Surgery, Hospital Althaia Manresa. Manresa, Barcelona, Spain
Department of Trauma and Orthopaedic Surgery, Hospital Nostra Senyora de Meritxell, Andorra

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Héctor José Aguado Department of Trauma and Orthopaedic Surgery, Hospital Clínico Universitario de Valladolid. Valladolid, Spain
Universidad de Valladolid, Valladolid, Spain

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Arantxa Capel Agundez Department of Trauma and Orthopaedic Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain

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Alina Ortega-Briones Department of Trauma and Orthopaedic Surgery, Hospital Clínico Universitario de Valladolid. Valladolid, Spain

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Jorge Hassan Núñez Department of Trauma and Orthopaedic Surgery, Hospital, Universitari Mútua Terrassa, Terrassa, Barcelona, Spain
Universidad Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain

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the PISCO Investigators †
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the PISCO Investigators

fracture in the presence of a pre-existing non-prosthetic implant ( 4 , 5 ). Even with implant improvement, several reports have shown a potential risk of femoral fractures after osteosynthesis due to changes in bone elastic modulus, ‘stress riser’ effect

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Leonardo Tassinari I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Alberto Di Martino I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Matteo Brunello I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Valentino Rossomando I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Francesco Traina Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy
Orthopedics-Traumatology and Prosthetic Surgery and Hip and Knee Revision, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Cesare Faldini I Department of Orthopedic and Traumatology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Department of Biomedical and Neuromotor Science-DIBINEM, University of Bologna, Bologna, Italy

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Purpose

  • Leg length discrepancy (LLD) is a common complication following total hip arthroplasty (THA). The direct anterior approach (DAA) for THA is gaining popularity due to its advantages, but there is limited research on the incidence and size of LLD. This systematic review aims to explore the differences in LLD between DAA and other approaches, as well as the techniques to control LLD in DAA.

Methods

  • A comprehensive literature search was conducted to identify relevant studies comparing THA by DAA with other surgical approaches and investigating methods to control LLD in DAA, following PRISMA guidelines and a priori registration on PROSPERO (CRD42023412644). The quality of the included studies was assessed. Data on preoperative and postoperative LLD and other relevant outcomes were extracted and analyzed descriptively.

Results

  • In total, 29 studies were included in this systematic review. The majority (86%) were classified as level IV evidence. Comparisons between DAA and posterior approach (PA) or anterolateral approach (ALA) showed DAA had lower rates of LLD >10 mm compared to PA and ALA. Different pre- and intra-operative techniques were evaluated, but no consensus on the best method for preventing LLD in DAA was reached.

Conclusion

  • DAA shows comparable or superior results in the prevention of LLD compared to other surgical approaches. Supine patient placement, direct leg measurement, and the use of IF contribute to these outcomes. Intraoperative fluoroscopy with a grid and preoperative planning offers a good option, especially for training purposes, but its role in preventing LLD by experienced DAA surgeons needs further investigation.

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Hanna Wellauer Department of Orthopaedic Surgery and Traumatology, HFR Fribourg Hospital, University of Fribourg, Fribourg, Switzerland
Division of Orthopaedics and Trauma Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland

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Roman Heuberger RMS Foundation, Bettlach, Switzerland

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Emanuel Gautier Department of Orthopaedic Surgery and Traumatology, HFR Fribourg Hospital, University of Fribourg, Fribourg, Switzerland

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Moritz Tannast Department of Orthopaedic Surgery and Traumatology, HFR Fribourg Hospital, University of Fribourg, Fribourg, Switzerland

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Hubert Steinke Institute for the History of Medicine, University of Bern, Bern, Switzerland

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Peter Wahl Division of Orthopaedics and Trauma Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland
Faculty of Medicine, University of Berne, Berne, Switzerland

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five years (author's transl) . Zeitschrift für Orthopädie und Ihre Grenzgebiete 1978 116 285 – 293 . 18. Barrack RL . Modularity of prosthetic implants . Journal of the American Academy of Orthopaedic Surgeons 1994 2 16 – 25 . ( https

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Charles Rivière MSK Lab, Imperial College London, UK; South West London Elective Orthopaedic Center, UK

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Stefan Lazic South West London Elective Orthopaedic Center, UK

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Loïc Villet Centre de l’arthrose, Merignac, France

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Yann Wiart Unfallchirurgie, Theresienkrankenhauss Mannheim, Germany

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Sarah Muirhead Allwood London Hip Unit, UK

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Justin Cobb MSK Lab, Imperial College London, UK

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° anteversion, as they found it reduced the risk of prosthetic hip dislocation. While those initial surgical techniques made for popular and clinically successful total joint replacements, many complications have remained, most notably the functional

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