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Hélder Pereira Orthopedic Department of Póvoa de Varzim - Vila do Conde Hospital Centre, Vila do Conde, Portugal
Ripoll y De Prado Sports Clinic, Murcia-Madrid, FIFA Medical Centre of Excellence, Madrid, Spain
International Centre of Sports Traumatology of the Ave, Vila do Conde, Portugal
3Bs Research Group, I3Bs, Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Barco, Guimarães, Portugal
ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal

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Ibrahim Fatih Cengiz 3Bs Research Group, I3Bs, Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Barco, Guimarães, Portugal
ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal

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Sérgio Gomes International Centre of Sports Traumatology of the Ave, Vila do Conde, Portugal

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João Espregueira-Mendes 3Bs Research Group, I3Bs, Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Barco, Guimarães, Portugal
ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal
Clínica do Dragão, Espregueira-Mendes Sports Centre, FIFA Medical Centre of Excellence, Porto, Portugal
Orthopedic Department, University of Minho, Braga, Portugal

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Pedro L. Ripoll Ripoll y De Prado Sports Clinic, Murcia-Madrid, FIFA Medical Centre of Excellence, Madrid, Spain

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Joan C. Monllau Orthopaedic Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain

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Rui L. Reis 3Bs Research Group, I3Bs, Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Barco, Guimarães, Portugal
ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal
The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Avepark, Barco, Guimarães, Portugal

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J. Miguel Oliveira 3Bs Research Group, I3Bs, Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Barco, Guimarães, Portugal
ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal
Orthopaedic Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain
The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Avepark, Barco, Guimarães, Portugal

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been a gradual increase in indications for meniscal repair rather than meniscectomy. When preservation is no longer possible, replacement is the next step for symptomatic patients or those with evidence of systematic progression towards arthritis at a

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Xiaofeng Deng Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Haoran Xu Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Xiaoxia Hao Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Jiawei Liu Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Xingru Shang Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Tao Xu Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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. The progression of OA can cause a series of chronic and progressive symptoms including pain, morning stiffness, swelling, limited range of joint motion, and poor physical function, thus reducing a patient’s ability to perform activities of daily living

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Francisco Figueroa Hospital Sótero del Río, Santiago, Chile
Clínica Alemana-Universidad del Desarrollo, Santiago, Chile

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David Figueroa Hospital Sótero del Río, Santiago, Chile

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Rafael Calvo Hospital Sótero del Río, Santiago, Chile

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Alex Vaisman Clínica Alemana-Universidad del Desarrollo, Santiago, Chile
Hospital Padre Hurtado, Santiago, Chile

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João Espregueira-Mendes Clínica do Dragão, Espregueira-Mendes Sports Centre - FIFA Medical Centre of Excellence, Portugal; Dom Henrique Research Centre, Portugal
3Bs Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Portugal; ICVS/3Bs–PT Government Associate Laboratory, Portugal
Orthopaedics Department of Minho University, Portugal

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progression of degenerative arthritis. Indications Classical indications for MAT are patients with a symptomatic meniscal deficiency, without the presence of advanced degenerative changes. Any concurrent pathology such as localized osteochondral

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Alfonso Vaquero-Picado Department of Orthopaedic Surgery, ‘La Paz’ University Hospital, Spain

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, ‘La Paz’ University Hospital, Spain

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contact pressures between articular surfaces are observed when a meniscectomy is performed in comparison with an intact meniscus. 24 Meniscectomy has also been found to be strongly associated with the progression of articular cartilage damage in the

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Nikolaos K. Paschos University of California, Davis, USA

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Stephen M. Howell University of California, Davis, USA

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its importance. 8 Despite the frequency in development of OA post-ACL injury, one of the main issues is whether ACL reconstruction can minimise the risk of osteoarthritis progression. Indeed, the reported incidence of osteoarthritis post

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Riccardo D’Ambrosi IRCCS Orthopedic Institute Galeazzi, Milan, Italy

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Katia Corona Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy

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Germano Guerra Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy

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Simone Cerciello Department of Orthopaedics, A. Gemelli University Hospital Foundation IRCCS, Catholic University, Rome, Italy
Casa di Cura Villa Betania, Rome, Italy
Marrelli Hospital, Crotone, Italy

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Chiara Ursino IRCCS Policlinico San Martino, Genova, Italy

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Nicola Ursino IRCCS Orthopedic Institute Galeazzi, Milan, Italy

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Michael Hantes Department of Orthopaedic Surgery, Faculty of Medicine, University of Thessalia, University Hospital of Larissa, Larissa, Greece

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focus on functional bracing, early range of motion, protected weight-bearing and progression towards strengthening exercises and, of course, a gradual return to activities as the pain diminishes. Conservative treatment for a complete return to sports can

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Joanna Baawa-Ameyaw Department of Trauma and Orthopaedic Surgery, University College Hospital, London, UK
Department of Orthopaedic Surgery, The Princess Grace Hospital, London, UK

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Ricci Plastow Department of Trauma and Orthopaedic Surgery, University College Hospital, London, UK
Department of Orthopaedic Surgery, The Princess Grace Hospital, London, UK

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Fahima Aarah Begum Department of Trauma and Orthopaedic Surgery, University College Hospital, London, UK
Department of Orthopaedic Surgery, The Princess Grace Hospital, London, UK

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Babar Kayani Department of Trauma and Orthopaedic Surgery, University College Hospital, London, UK
Department of Orthopaedic Surgery, The Princess Grace Hospital, London, UK

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Hyder Jeddy Department of Trauma and Orthopaedic Surgery, University College Hospital, London, UK
Department of Orthopaedic Surgery, The Princess Grace Hospital, London, UK

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Fares Haddad Department of Trauma and Orthopaedic Surgery, University College Hospital, London, UK
Department of Orthopaedic Surgery, The Princess Grace Hospital, London, UK

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: 810 – 817 . 6. Nakamae A Adachi N Deie M et al. Risk factors for progression of articular cartilage damage after anatomical anterior cruciate ligament reconstruction: a second-look arthroscopic evaluation . J

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Mohammad Shahid St Michael’s Hospital, 30 Bond Street, Toronto, M5B1W8, Canada
Walsall Manor Hospital, Moat Road, Walsall, WS2 9PS, UK

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Rik Kundra St Michael’s Hospital, 30 Bond Street, Toronto, M5B1W8, Canada
Walsall Manor Hospital, Moat Road, Walsall, WS2 9PS, UK

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2010 ; 34 : 589 - 597 . 59 Saito M , Takahashi KA , Arai Y , et al. . Intraarticular administration of platelet-rich plasma with biodegradable gelatin hydrogel microspheres prevents osteoarthritis progression in the

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Mahmut Nedim Doral Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Department of Sports Medicine, Ankara, Turkey

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Onur Bilge Konya N.E. University, Meram Faculty of Medicine, Department of Orthopaedics and Traumatology, Department of Sports Medicine, Konya, Turkey

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Gazi Huri Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey

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Egemen Turhan Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey

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René Verdonk Ghent University, Faculty of Medicine, Department of Orthopaedics and Traumatology, De Pintelaan, Ghent, Belgium

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The short-term clinical results were found to be highly successful, but a high rate of progression to osteoarthritis at long term was also demonstrated. 36 Moreover, even with degenerative and traumatic meniscal tears, recent, relatively high LoE

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