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Julien Favre Swiss BioMotion Laboratory, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

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Brigitte M. Jolles Swiss BioMotion Laboratory, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Institute of Microengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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be positively associated with pain intensity. 19 Interestingly, beyond cross-sectional research, a few longitudinal studies have highlighted an association with disease progression, where OA progressed faster in patients with higher mid

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Cécile Batailler Hôpital de la Croix Rousse, Hospices Civils de Lyon, France

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Philippe Neyret Burjeel Hospital, Abu Dhabi; UAE

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operation to optimize patellar tracking. Osteoarthritis Although the deepening or recession trochleoplasty is effective in reducing anterior knee pain, it does not halt the progression of patellofemoral arthritis, although the follow-up of the above

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital - IdiPaz, Spain

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Primitivo Gómez-Cardero Department of Orthopaedic Surgery, La Paz University Hospital - IdiPaz, Spain

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complications. 31 The overall re-operation rate per 100 component years was comparable between mobile and fixed bearings. Nevertheless, the mobile bearings were more prone to re-operations in patients from aseptic loosening, progression of OA, and implant

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Maurilio Marcacci Rizzoli Orthopaedic Institute - II Clinic- Biomechanics Laboratory, Bologna, Italy

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Luca Andriolo Rizzoli Orthopaedic Institute - II Clinic- Biomechanics Laboratory, Bologna, Italy

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Elizaveta Kon Rizzoli Orthopaedic Institute - II Clinic- Biomechanics Laboratory, Bologna, Italy

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Nogah Shabshin Carmel Medical Center, Department of Radiology, Haifa, Israel

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Giuseppe Filardo Rizzoli Orthopaedic Institute - II Clinic- Biomechanics Laboratory, Bologna, Italy

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infiltration of synovial fluid, detachment and fragmentation of the osteochondral fragment, followed by ON changes in the disconnected area 42 ( Fig. 6 ). Fig. 6 Progression of an insufficiency fracture over ten months. Coronal PD fat suppression (a

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Stein J. Janssen Department of Orthopaedic Surgery, Academic Medical Center, Amsterdam Movement Sciences, Amsterdam, The Netherlands

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Iris van Oost Department of Orthopaedic Surgery, FORCE (Foundation for Orthopaedic Research Care Education), Amphia Hospital, Breda, The Netherlands

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Stefan J.M. Breugem Department of Orthopaedic Surgery, Bergman Clinics, Naarden, The Netherlands

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Rutger C.I. van Geenen Department of Orthopaedic Surgery, FORCE (Foundation for Orthopaedic Research Care Education), Amphia Hospital, Breda, The Netherlands

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progression (1.4%), aseptic loosening (1.3%), bearing dislocation (0.58%), pain (0.57%), and infection (0.47%). 3 Proper patient selection is key for success; ideal candidates present with painful isolated bone-on-bone anteromedial osteoarthritis with a

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Michele Vasso Concordia Hospital for Special Surgery, Rome, Italy

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Alexander Antoniadis Bürgerspital Solothurn, Switzerland

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Naeder Helmy Bürgerspital Solothurn, Switzerland

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activity level and/or younger age and final outcome of UKA. 11 , 20 , 36 Chondrocalcinosis Chondrocalcinosis is considered to be a contraindication for UKA as it is thought to be associated with more rapid progression of contralateral OA. In

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Claudio Legnani IRCCS Istituto Ortopedico Galeazzi, Sports Traumatology and Minimally Invasive Articular Surgery Center, Milan Italy

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Andrea Parente IRCCS Istituto Ortopedico Galeazzi, Hip and Knee Arthroplasty Surgery Center, Milan, Italy

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Franco Parente IRCCS Istituto Ortopedico Galeazzi, Hip and Knee Arthroplasty Surgery Center, Milan, Italy

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Alberto Ventura IRCCS Istituto Ortopedico Galeazzi, Sports Traumatology and Minimally Invasive Articular Surgery Center, Milan Italy

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(rate) Rees et al. (3) 2001 18 II PCS 68 ± 8.0 N/a 5.4 years (3.6–7.1) Mobile-bearing medial UKR 66 Five revisions (27.7%) to TKR due to persistent pain, in one case associated to progression of OA on the lateral

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Jonathan G. Robin Box Hill Hospital, Eastern Health Network, Australia

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Philippe Neyret Lyon 1 University, France

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to the ACL deficiency. Where instability is the overriding symptom in the setting of varus malalignment or pre-OA, an ACL reconstruction in combination of HTO may be performed to protect the ACL graft and slow the progression of any arthritis ( Fig. 2

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Gareth G. Jones MSk Lab, Imperial College London, London, UK

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Martin Jaere MSk Lab, Imperial College London, London, UK

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Susannah Clarke MSk Lab, Imperial College London, London, UK

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Justin Cobb MSk Lab, Imperial College London, London, UK

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, both as an adjunct in the treatment of meniscal and ligamentous pathology, and potentially as a means of delaying or preventing the progression of arthritis in the varus knee. 25 , 26 However, before HTO becomes mainstream, the procedure needs to

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Gerardo Fusco Humanitas University, Department of Biomedical Sciences, Milan, Italy
IRCCS Humanitas Research Hospital, Milan, Italy
These authors contributed equally to the article and should both be considered first authors

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Francesco M. Gambaro Humanitas University, Department of Biomedical Sciences, Milan, Italy
IRCCS Humanitas Research Hospital, Milan, Italy
These authors contributed equally to the article and should both be considered first authors

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Berardo Di Matteo Humanitas University, Department of Biomedical Sciences, Milan, Italy
First Moscow State Medical University – Sechenov University, Moscow, Russia

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Elizaveta Kon Humanitas University, Department of Biomedical Sciences, Milan, Italy
IRCCS Humanitas Research Hospital, Milan, Italy

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the knee and hip. The aim of OA treatment is to control symptoms until the severity of the condition mandates surgical intervention; an early therapy may be a vital step for delaying the progression to end-stage disease. 1 Symptomatic control can

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