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Ilse Degreef Institute for Orthopedic Research and Training (IORT), Department of Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, Belgium

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Kira Vande Voorde Institute for Orthopedic Research and Training (IORT), Department of Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, Belgium

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Maarten Van Nuffel Institute for Orthopedic Research and Training (IORT), Department of Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, Belgium

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, recurrence in DD is not uniformly defined. There is a difference between residual deformity, extension (or progression) of the disease and true recurrence of nodules and strands in the operated field, and at best, definitions are consensus based ( 8 , 9

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Rita Grazina Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Sérgio Teixeira Serviço de Cirurgia Plástica, Reconstrutiva e Estética e Unidade de Queimados, Centro Hospitalar de São João, Portugal

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Renato Ramos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Henrique Sousa Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Andreia Ferreira Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Rui Lemos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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any digit. 6 It usually starts in the palm of the hand and then presents a distal progression ( Fig. 1 ). 2 Skin changes might also be present, namely pitting and dimpling. 2 Fig. 1. Volar view of the hand showing a cord

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Andrea Fidanza Unit of Orthopaedics and Traumatology - Department of life, Health & Environmental Sciences, University of L’Aquila, Italy
Hand Unit, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

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Stefano Necozione Unit of Clinical Epidemiology - Department of life, Health & Environmental Sciences, University of L’Aquila, Italy

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Lorenzo Garagnani Hand Unit, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
Faculty of Life Sciences and Medicine, King’s College London, London, UK

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procedure that relieves pain but does not stop the progression of the disease; therefore, some of the reported additional surgical procedures may have been carried out due to the disease progression itself and not only due to a failure of the denervation

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David Eckerdal Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden
Department of Clinical Sciences - Orthopedics, Lund University, Lund, Sweden

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Hendrik Pakosta Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden

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Muhanned Ali Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden
Department of Clinical Sciences - Orthopedics, Lund University, Lund, Sweden

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Isam Atroshi Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden
Department of Clinical Sciences - Orthopedics, Lund University, Lund, Sweden

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superior in clinical improvement and complications No significant difference Less recurrence and disease progression after collagenase † No standard deviation or other distribution measure reported; ↑ Data from the 3-month follow

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Maurizio Calcagni University Hospital Zürich, Switzerland

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Thomas Giesen University Hospital Zürich, Switzerland

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head-only replacement), erosion of the sigmoid notch was observed in one-third of the cases with no apparent progression after five years. Discussion This report is limited by the poor quality of several articles and the lack of homogeneity in

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Jonny K. Andersson Department of Hand Surgery, Sahlgrenska University Hospital, Göteborg, Sweden and Department of Orthopaedics, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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angle > 60° and SL gap > 3 mm on clenched-fist or ulnar-deviation radiographs). For this development and progression to occur, an additional tear or gradual, continuous elongation of the secondary ligament stabilisers of the SL ligament is needed. 6

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Shankar Aissvarya Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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King-Hwa Ling Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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Manohar Arumugam Department of Orthopaedics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
School of Medicine, Faculty of Medicine and Health Sciences, Taylor's University, Selangor, Malaysia

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Karuppiah Thilakavathy Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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273, suggests that the phenotype of the myofibroblasts may be linked to cord thickening during DC progression. It is also likely that collagen turnover in the cord tissue is significantly higher than in other regions of the body, which could explain

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Jonny K Andersson Department of Surgery, Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar
Department of Orthopaedics, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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Pelle Gustafson Department of Clinical Sciences – Orthopedics, Lund University, Lund, Sweden
The Swedish National Patient Insurance Company, Stockholm, Sweden

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Philippe Kopylov Department of Clinical Sciences – Orthopedics, Lund University, Lund, Sweden
Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden

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://doi.org/10.1177/03635465000280061001 ) 7 Watson HK Weinzweig J Zeppieri J . The natural progression of scaphoid instability . Hand Clinics 1997 13 39 – 49 . ( https://doi.org/10.1016/S0749-0712(2100079-2 ) 8 Watson HK Ballet FL . The SLAC

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Patrick Houvet Institut Français de Chirurgie de la Main, Paris, France

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patients with hypermobility. LC fusion is an option, and this does not progress into stiffness for these particular patients. 51 2) Arthritis: a) Sooner or later, the progression of scapholunate instability with arthritis (SLAC

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Daniel Herren Schulthess Klinik, Zurich, Switzerland

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affected joints with OA does not appear, to date, to alter the appearance of OA in unaffected joints, or delay the progression of OA elsewhere. In the pathophysiology of the disease, catabolic cytokines and anabolic growth factors play key roles in the

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