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Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China
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group, without TXA used in the control group. Outcome index: intraoperative blood loss (IBL), output and duration of postoperative drainage, total blood loss (TBL), postoperative hospital stay, postoperative blood parameters, postoperative blood
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indication for further postoperative rehabilitation treatment and whether its type and duration have an impact on the clinical and functional outcome after spine surgery ( 4 , 7 , 10 , 19 , 20 ). The aim of this review is to resume the most recent
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’ condition TXA administration Outcomes He et al. ( 11 ) Low Degenerative conditions 10 mg/kg i.v. before skin incision + 6–8 mg/kg/h i.v. during the surgery IBL, total postoperative drainage, time for drainage removal, hospital stay
NeuroGen Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, Porto, Portugal
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CINTESIS@RISE - Health Research Network, MEDCIDS, Faculty of Medicine, University of Porto, Porto, Portugal
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Hospital das Forças Armadas, Porto, Portugal
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Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, Porto, Portugal
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CINTESIS@RISE - Health Research Network, MEDCIDS, Faculty of Medicine, University of Porto, Porto, Portugal
Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, Porto, Portugal
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a report of at least one of the following outcomes: operative time, estimated blood loss, post-operative bedtime or hospital length of stay, back or leg pain (assessed through visual analog scale – VAS), disability (assessed through Oswestry
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a material benefit for minimally invasive surgery, but two of the analysed trials reported outcome data from surgery using tubular retractor systems that are not comparable with those from the studies reported below. Anterior endoscopic surgery
Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
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iatrogenic injury, accelerate postoperative rehabilitation and improve clinical outcome ( 32 ). MIS-TLIF has been proved to achieve a similar fusion rate comparable to traditional TLIF, while preserving the physiological function of paravertebral soft tissues
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association between postoperative instability and poor outcomes is controversial. Charafeddine et al, 20 Herno et al, 21 Epstein 15 and more recently Martin et al 22 concluded that postoperative instability was not always associated with
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degeneration, spondylolisthesis, or scoliosis) and studies that report at least one of the following outcomes of interest: postoperative ODI, postoperative lower back or leg pain on visual analog scale (VAS) or numerical rating scale (NRS), and/or MacNab
Centre for Spinal Surgery, Queens Medical Centre, Nottingham University NHS Trust, Nottingham, UK
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-significant associations with postoperative outcome. 31 Open access This article is distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC BY-NC 4.0) licence ( https://creativecommons.org/licenses/by-nc/4
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Proposed advantages of these techniques regarding the lower incidence of iatrogenic instability and post-operative back pain were reported, but definitive conclusions are limited by poor methodology, and poor reports of the outcome measures in the included
