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Introduction Subchondral bone is the bedrock of a joint on which sits the articular cartilage. Traditionally, osteoarthritis (OA) has been considered to be wear and tear of articular cartilage, but more recent evidence has shown that
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Introduction The main pathological changes of osteoarthritis (OA) are related to cartilage degeneration, subchondral bone thickening, synovitis, and structural lesions of the joint capsules, ligaments, and associated muscles ( 1 , 2 ). The
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Introduction Many patients present to orthopaedic surgeons with a painful knee attributed to osteoarthritis of the medial compartment, where the lateral compartment and patella-femoral joint are relatively spared. Traditionally, the treatment
Sengkang General Hospital, Singapore
Joint first authors
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Introduction Osteoarthritis (OA) is a global disease with a variety of pathophysiological factors. 1 These factors can be mechanical, biological or a combination of both. Cardinal features of OA include loss of joint space and cartilage
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Applied and Translational Research (ATR) Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Università della Svizzera Italiana, Faculty of Biomedical Sciences, Lugano, Switzerland
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Introduction Knee osteoarthritis (OA) is one of the most common orthopedic diseases and represents a major cause of knee pain and disability in older adults ( 1 , 2 ). The prevalence of this degenerative condition is currently rising, with a
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Institute of Microengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Introduction Osteoarthritis (OA), the most common type of arthritis, is a disease causing pain, deformity, and dysfunction of the joints. This condition affects a constantly increasing portion of the population, inducing serious socio
Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China
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Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China
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Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China
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Guangdong Second Traditional Chinese Medicine Hospital (Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine), Guangzhou, China
The fifth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China
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Introduction Osteoarthritis (OA) is a severe and painful joint disease that limits daily activities and reduces quality of life. OA is estimated to be the third leading cause of disability, affecting approximately 350 million people worldwide
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Introduction Risks for the future are a source of concern for any trauma patient and are included in the settlement of personal injury claims. In the case of ankle fractures, this mainly concerns the risk of osteoarthritis and the resulting
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talus (TTS). In 2008, Hayashi et al 40 used the same radiographic technique to assess ankles suffering from primary varus osteoarthritis and added the angle between the talar dome and the posterior joint facet of the calcaneus (subtalar inclination
IRCCS Humanitas Research Hospital, Milan, Italy
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IRCCS Humanitas Research Hospital, Milan, Italy
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First Moscow State Medical University – Sechenov University, Moscow, Russia
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IRCCS Humanitas Research Hospital, Milan, Italy
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Introduction Osteoarthritis (OA) is a degenerative disease with a tendency to worsen over time, characterized by articular cartilage degradation, subchondral damage, and bone remodelling, most commonly affecting weight-bearing joints such as
