Olga D. Savvidou
Olga D. Savvidou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panagiotis Koutsouradis
Panagiotis Koutsouradis
Department of Orthopaedic Surgery, 417 Veterans Hospital (NIMTS), Athens, Greece
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George D. Chloros
George D. Chloros
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Ioannis Papanastasiou
Ioannis Papanastasiou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Thomas Sarlikiotis
Thomas Sarlikiotis
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Aggelos Kaspiris
Aggelos Kaspiris
Laboratory of Molecular Pharmacology/ Sector for Bone Research, School of Health Sciences, University of Patras, Patras, Greece
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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radiofrequency thermal ablation (RFA) or arthroscopic excision. 8 Moreover, the management and prognosis of patients with malignant tumours, such as Ewing sarcoma and osteosarcoma, have improved thanks to the adjuvant chemotherapeutic protocols and improved
Chengxiang Li
Chengxiang Li
Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
University of Basel, Basel, Switzerland
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University of Basel, Basel, Switzerland
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Fatime Krasniqi
Fatime Krasniqi
Department of Oncology, University Hospital Basel, Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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Ricardo Donners
Ricardo Donners
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Department of Radiology, University Hospital Basel, Basel, Switzerland
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Department of Radiology, University Hospital Basel, Basel, Switzerland
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Christoph Kettelhack
Christoph Kettelhack
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland
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Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland
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Andreas H Krieg
Andreas H Krieg
Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
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signal intensity on fluid-sensitive MRI sequences suggest necrosis and a favorable response, while a reduction in size can be present. Overall, larger SS usually show features typical for a malignant soft tissue tumor with potentially suggestive
Olga D. Savvidou
Olga D. Savvidou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panagiotis Koutsouradis
Panagiotis Koutsouradis
Department of Orthopaedic Surgery, Mediterraneo Hospital, Athens, Greece
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Ioanna K. Bolia
Ioanna K. Bolia
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Angelos Kaspiris
Angelos Kaspiris
Laboratory of Molecular Pharmacology/Sector for Bone Research, School of Health Sciences, University of Patras, Patras 26504, Greece
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George D. Chloros
George D. Chloros
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece
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Introduction Soft tissue tumours around the elbow are rare, with an incidence of around 3.8% of all soft tissue tumours. 1 Benign soft tissue tumours occur approximately 10 times more frequently than malignant ones. 2 Nevertheless
Olga Savvidou
Olga Savvidou
First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
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These authors contributed equally to this manuscript
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Olympia Papakonstantinou
Olympia Papakonstantinou
Second Department of Radiology, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Athens, Greece
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These authors contributed equally to this manuscript
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Eleftheria Lakiotaki
Eleftheria Lakiotaki
First Department of Pathology, National and Kapodistrian University of Athens, LAIKON General Hospital, Athens, Greece
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These authors contributed equally to this manuscript
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Dimitra Melissaridou
Dimitra Melissaridou
First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
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Pinelopi Korkolopoulou
Pinelopi Korkolopoulou
First Department of Pathology, National and Kapodistrian University of Athens, LAIKON General Hospital, Athens, Greece
Co-senior authors
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
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MO in comparison to other bone or soft tissue malignant tumours that emerge in the differential diagnosis of a rapid-growing muscular mass. Awareness that MO may simulate bone and soft tissue tumours can help orthopaedic surgeons in a prompt diagnosis
Robert Grimer
Robert Grimer
The Royal Orthopaedic Hospital, Birmingham, UK
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Michael Parry
Michael Parry
The Royal Orthopaedic Hospital, Birmingham, UK
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Steven James
Steven James
The Royal Orthopaedic Hospital, Birmingham, UK
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maybe distressed when the pathologist reports that the lesion which they thought was benign, is in fact malignant! 2 Almost always the surgeon will have ‘shelled out’ the lump and will usually confidently say that they ‘have got it all out’. In the
James Plant
James Plant
Royal National Orthopaedic Hospital, Stanmore, UK
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Stephen Cannon
Stephen Cannon
Royal National Orthopaedic Hospital, Stanmore, UK
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necessary to maintain a high index of suspicion for tumours in order to not miss the diagnosis when it arises. Sarcomas are malignant tumours of mesodermal origin. They are frequently aggressive, and more prevalent in a younger patient group compared to
Daniel Kotrych
Daniel Kotrych
Department of Orthopedics, Traumatology and Orthopedic Oncology, Pomeranian Medical University, Szczecin, Poland
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Andrea Angelini
Andrea Angelini
Department of Orthopedics and Orthopedic Oncology, University of Padova, Italy
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Andrzej Bohatyrewicz
Andrzej Bohatyrewicz
Department of Orthopedics, Traumatology and Orthopedic Oncology, Pomeranian Medical University, Szczecin, Poland
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Pietro Ruggieri
Pietro Ruggieri
Department of Orthopedics and Orthopedic Oncology, University of Padova, Italy
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primary malignant bone tumors without compromising the oncological outcome ( 7 , 8 , 9 ). Prosthetic reconstructions after primary bone tumor removal can be divided into two groups based on (i) availability of modular implants or (ii) custom implants for
Olga Savvidou
Olga Savvidou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece
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These authors contributed equally to this manuscript
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Olympia Papakonstantinou
Olympia Papakonstantinou
Second Department of Radiology, National and Kapodistrian University of Athens, Medical School, Attikon University General Hospital, Athens, Greece
These authors contributed equally to this manuscript
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These authors contributed equally to this manuscript
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Eleftheria Lakiotaki
Eleftheria Lakiotaki
First Department of Pathology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece
These authors contributed equally to this manuscript
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These authors contributed equally to this manuscript
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Ioannis Zafeiris
Ioannis Zafeiris
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece
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Dimitra Melissaridou
Dimitra Melissaridou
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece
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Pinelopi Korkolopoulou
Pinelopi Korkolopoulou
First Department of Pathology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece
Co-senior authors
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Panayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece
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and cartilage. 1 – 4 Osseous surface bone tumours include benign tumours such as osteoma, osteoid osteoma and osteoblastoma, and the malignant category of surface osteosarcomas (parosteal, periosteal and high-grade osteosarcoma), while the
Ajay Puri
Ajay Puri
Department of Surgery, Tata Memorial Hospital, HBNI, Mumbai
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Chondrosarcoma, a tumour of cartilage producing cells, comprises a heterogeneous group of malignant cartilaginous tumours. It is the most common sarcoma of bone in patients above the age of 20 years and predominantly affects individuals in the
Antal Imre
Antal Imre
Department of Orthopaedics, Semmelweis University, Budapest, Hungary
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Sápi Zoltán
Sápi Zoltán
Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest
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Szendrői Miklós
Szendrői Miklós
Department of Orthopaedics, Semmelweis University, Budapest, Hungary
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, 14 ). GCTB may metastasise to the lungs in 1–4% of all cases ( 15 , 16 ) even when histological features appear benign. Based on results from large cohorts, malignant transformation of GCTB occurred in about 1 to 1.6% of cases mainly during the
