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Han Ling Tan Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Tunku Sara Ahmad Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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C Sankara Kumar Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Yohan Khirusman Adnan Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Lai Meng Looi Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Jayaletchumi Gunasagaran Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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, 10 , 11 ). Malignant transformation has never been reported in this tumor. There are other differential tumors with myxoid histological appearance or tumors with distal extremity predilection ( Tables 1 and 2 ). Table 1 Summarized list of

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Elena Bravo Plastic Surgery Department, Hospital Universitario La Paz, Madrid, Spain

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Raul Barco Upper Limb Unit, Orthopedic Surgery Department, Hospital Universitario La Paz, Madrid, Spain

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E. Carlos Rodríguez-Merchán Haemophilia Orthopedic Unit, Orthopedic Surgery Department, Hospital Universitario La Paz, Madrid, Spain

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-ossifying fibroma. 25 Some of the most common haematologic disorders may be detected in radiographs of the hand, especially in plasma cell dyscrasias and proliferative malignant diseases. 26 However, it is infrequent to see haemophilic arthropathy or cysts

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Rita Grazina Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Sérgio Teixeira Serviço de Cirurgia Plástica, Reconstrutiva e Estética e Unidade de Queimados, Centro Hospitalar de São João, Portugal

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Renato Ramos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Henrique Sousa Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Andreia Ferreira Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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Rui Lemos Serviço de Ortopedia e Traumatologia, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal

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%, rising to 29% at 75 years. 4 Aetiology The aetiology of Dupuytren’s disease is as yet poorly understood. 6 In fact, despite being a benign disorder, it has similarities with malignant processes. In the early stages of the disease, the

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Ilse Degreef Department of Orthopaedic, Hand Unit, Leuven University Hospitals, Gasthuisberg, Herestraat, Leuven, Belgium

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Donald H Lalonde Division of Plastic Surgery, Dalhousie University, Saint John, New Brunswick, Canada

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patient has no sedation or general anesthesia. Local anesthesia is preferred for its elimination of systemic risks of sedation: nausea, vomiting, aspiration pneumonia, respiratory suppression, thromboembolism, cardiovascular effects, malignant hyperthermia

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Shankar Aissvarya Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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King-Hwa Ling Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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Manohar Arumugam Department of Orthopaedics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
School of Medicine, Faculty of Medicine and Health Sciences, Taylor's University, Selangor, Malaysia

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Karuppiah Thilakavathy Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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emerging therapeutic target in malignant melanoma . Cancer Biology and Therapy 2011 12 1032 – 1049 . ( https://doi.org/10.4161/cbt.12.12.18442 ) 51 Meng XM Nikolic-Paterson DJ & Lan HY . TGF-β: the master regulator of fibrosis . Nature Reviews

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