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G. Ulrich Exner Orthopaedie Zentrum Zuerich (ozz), Seestrasse 259, CH 8038 Zurich, Switzerland

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Michael O. Kurrer Gemeinschaftspraxis fuer Pathologie, Caecilienstrasse 3, CH 8032 Zurich, Switzerland

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Nadja Mamisch-Saupe Klinik Hirslanden, Department of Musculoskeletal Radiology, Witellikerstrasse 40, 8032 Zurich, Switzerland

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Stephen R. Cannon BMI The Clementine Churchill Hospital, Sudbury Hill, Harrow, Middlesex HA1 3RX, Great Britain

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procedure, but it can have the potential of adversely affecting the outcome of the case, particularly in malignant tumours. The importance of proper planning and performance of appropriate biopsy in musculoskeletal lesions is well-known and a recent

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Lars Nonnenmacher Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Maximilian Fischer Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Lyubomir Haralambiev Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Sander Bekeschus ZIK plasmatis, Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany

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Frank Schulze Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Georgi I Wassilew Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Janosch Schoon Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Johannes C Reichert Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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.4 per million in the general population ( 55 ). With an incidence of about 3 per million for each entity, Ewing’s sarcoma (ES) and chondrosarcoma (CS) are two more common malignant bone tumours usually diagnosed in childhood and adolescence

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Andreas F. Mavrogenis First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece

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Vasilios G. Igoumenou First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece

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Thekla Antoniadou First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece

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Panayiotis D. Megaloikonomos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece

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George Agrogiannis Second Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Greece

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Periklis Foukas Second Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Greece

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Sotirios G. Papageorgiou Second Department of Internal Medicine, Hematology Unit, National and Kapodistrian University of Athens, School of Medicine, Greece

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reticulohistiocytoma; and 3) Class III including malignant histiocytic disorders, acute monocytic leukaemia (FAB M5), malignant histiocytosis and true histiocytic lymphoma. The Histiocyte Society has proposed the following classification for histiocytic

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Michalis Panteli Academic Department of Trauma & Orthopaedics, Leeds General Infirmary; School of Medicine, University of Leeds, UK

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Peter V. Giannoudis Academic Department of Trauma & Orthopaedics, Leeds General Infirmary; School of Medicine, University of Leeds, UK

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with high incidence of recurrence. 3 Following debridement, samples from the involved bone, sinus tract and surrounding tissues should be sent for pathological examination to ensure there are no malignant changes. 20 Even though the need for

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Guillermo Droppelmann Research Center on Medicine, Exercise, Sport and Health, MEDS Clinic, Santiago, RM, Chile
Health Sciences PhD Program, Universidad Católica de Murcia UCAM, Murcia, Spain
Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA

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Constanza Rodríguez Facultad de Medicina, Universidad Finis Terrae, Santiago, RM, Chile

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Carlos Jorquera Facultad de Ciencias, Escuela de Nutrición y Dietética, Universidad Mayor, Santiago, RM, Chile

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Felipe Feijoo School of Industrial Engineering, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile

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Algorithm Cohen et al. ( 17 ) France Rx Wrist fracture 637 1917 206 41 17 373 Bone View (Gleamer) Georgeanu et al. ( 18 ) Romania MRI Malignant bone tumors 23 2106 80 20 4 63 Res-Net 50 Hess

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Djandan Tadum Arthur Vithran Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

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Anko Elijah Essien Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China

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Masoud Rahmati Research Centre on Health Services and Quality of Life, Aix Marseille University, Marseille, France
Department of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad, Iran
Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Vali-E-Asr University of Rafsanjan, Rafsanjan, Iran

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Michael Opoku Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China

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Dong Keon Yon Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Republic of Korea
Department of Pediatrics, Kyung Hee University College of Medicine, Seoul, Republic of Korea

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Guillermo F López Sánchez Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain

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Ai Koyanagi Research and Development Unit, Parc Sanitari Sant Joan de Deu, Barcelona, Spain

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Lee Smith Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK

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Jae Il Shin Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea

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Wenfeng Xiao Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

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Shuguang Liu Department of Joint Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, China

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Yusheng Li Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

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experiments; v) study subjects with non-osteoporotic fractures; or non-vertebral fractures; vi) study subjects with secondary osteoporosis, such as (GIOP, malignant tumor associated bone diseases, bone metastases); vii) study subjects participants with

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Shaho Hasan Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Peter van Schie Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, The Netherlands

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Bart L Kaptein Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Jan W Schoones Walaeus Library, Leiden University Medical Centre, Leiden, The Netherlands

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Perla J Marang-van de Mheen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Safety & Security Science, Delft University of Technology, Delft, The Netherlands

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Rob G H H Nelissen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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bone resorption marker in focal malignant osteolysis ( 72 ). In the first 6 months, urinary NTX appeared to be elevated in all patients following THA or TKA, but levels returned to normal thereafter, making these biomarkers potentially usable to

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İlker Eren Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Cemil Cihad Gedik Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Uğur Kılıç Koç University, School of Medicine, Istanbul, Turkey

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Berk Abay Koç University, School of Medicine, Istanbul, Turkey

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Olgar Birsel Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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Mehmet Demirhan Koç University, School of Medicine, Department of Orthopaedics and Traumatology, Istanbul, Turkey

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total i.v. anaesthesia with propofol and remifentanil infusions at suitable lowest doses. Although there is no known increased risk for malignant hyperthermia ( 60 ), it is prudent to have dantrolene in the armamentarium. Remifentanil is the preferred

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Jasmine N. Levesque Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada

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Ajay Shah Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada

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Seper Ekhtiari Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada

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James R. Yan Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada

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Patrick Thornley Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada

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Dale S. Williams Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada

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) 2016 ; 95 : e2461 . 41. Wang F Zhu J Peng X Su J . The application of 3D printed surgical guides in resection and reconstruction of malignant bone tumor . Oncol Lett 2017 ; 14 : 4581 – 4584 . 42

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