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least one complication, which is important when compared with the 21.2% rate of placebo. Most complications are mild/moderate and include bruising, injection-site haemorrhage or pain, upper limb pain, tenderness, ecchymosis, pruritus, swelling, skin
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, clavicle plating, and major limb amputations ( 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 ). Although the cost benefits of this approach in these cases are evident, the absolute indications for these procedures are not yet completely clear and
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vessels, poor perfusion and weakened skin barrier are more likely to present in the medical cabinet with an infected upper limb. Newborns are also prone to hand infections due to their undeveloped immune systems and their sharp nail-ends that can injure
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excursion of the nerve trunk in connection with movement of the limb. Furthermore, a nerve trunk can be surgically mobilised over a certain distance without restriction of the blood flow. The fundamental difference between the epineurial blood vessels and
