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inflammation, release bone morphogenetic protein (BMP) and transforming growth factor (TGF), and promote the mesenchymal stem cells to differentiate into chondrocytes and osteoblasts, which at last participate in the process of bone formation and result in MO
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Department of Trauma & Orthopaedics, University of Leeds, Leeds, United Kingdom of Great Britain and Northern Ireland
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regarding heterotopic ossification with the injected marrow migrating away from the injection site when inserted in isolation ( 18 ). The anterior iliac crest remains the most common site for the harvest of autogenous bone grafts, with both cancellous and
Bucharest Emergency Clinical Hospital, Romania
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University Emergency Hospital Bucharest, Romania
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Bucharest Emergency Clinical Hospital, Romania
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University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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development was aimed at bone defect reconstruction and treatment of nonunion. Medical-grade calcium sulphate displays excellent biocompatibility and a degradation profile remarkably close to bone formation, lasting between four to eight weeks. 43 , 44
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frequent finding and is not indicative of implant failure as long as there in no progression in bone loss. It has rather been thought of as the radiological appearance of fibrous membrane formation secondary to cement-bone interactions ( Fig. 4 ). 38
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-out, loss of reduction, implant mal-positioning); (6) degree of bone healing such as osseointegration, loosening, deformity, mal-union, nonunion, osteonecrosis or heterotopic bone formation; (7) clinical outcomes assessed by the physician through history and